about
P688
Identification of the gene for a novel liver-related putative tumor suppressor at a high-frequency loss of heterozygosity region of chromosome 8p23 in human hepatocellular carcinomaThe Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitorCharacterization of interactions between PinX1 and human telomerase subunits hTERT and hTRTelomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongationHuman PinX1 mediates TRF1 accumulation in nucleolus and enhances TRF1 binding to telomeresPinX1 is recruited to the mitotic chromosome periphery by Nucleolin and facilitates chromosome congressionPinX1, a telomere repeat-binding factor 1 (TRF1)-interacting protein, maintains telomere integrity by modulating TRF1 homeostasis, the process in which human telomerase reverse Transcriptase (hTERT) plays dual rolesIncreased Stability of Nucleolar PinX1 in the Presence of TERTPinX1 is involved in telomerase recruitment and regulates telomerase function by mediating its localizationA shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins
P921
Q24290300-4F014F35-59E6-4885-A720-1CB31B3C3A9DQ24291889-079C5341-41FE-4175-B88D-4A2D762BEF63Q24304902-71F159EA-88C5-4C74-89A4-781D5BE11215Q24310189-50DC4B5C-983C-4091-9EBD-9DF1B42A9E4DQ24318525-6859876D-2EE3-489D-B3EF-81289D65917FQ24319168-E4263331-FCD6-4D69-B451-D395883B4400Q24319715-F15312CA-C565-44D9-AAA1-28A7E8C9A194Q24338508-A1B443A7-AC28-45EE-9709-35B5280762E8Q24339397-E20A0D41-1A2F-4E36-BD7E-2DBD56072C1DQ27649552-AE019B7E-35A4-40EA-BE4E-761F1860F1FA
P921
description
humanes Protein
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
proteinë
@sq
protèin
@ace
protéine humaine
@fr
بروتين بشري
@ar
name
PIN2 (TERF1) interacting telomerase inhibitor 1
@en
PIN2
@nl
type
label
PIN2 (TERF1) interacting telomerase inhibitor 1
@en
PIN2
@nl
altLabel
67-11-3 protein
@en
PIN2-interacting protein 1
@en
PIN2/TERF1-interacting telomerase inhibitor 1
@en
PINX1
@en
TRF1-interacting protein 1
@en
hepatocellular carcinoma-related putative tumor suppressor
@en
liver-related putative tumor suppressor
@en
pin2-interacting protein X1
@en
protein 67-11-3
@en
prefLabel
PIN2 (TERF1) interacting telomerase inhibitor 1
@en
PIN2
@nl
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ENSP00000318966
ENSP00000428242
ENSP00000428728
ENSP00000428853
ENSP00000429346
ENSP00000451145
ENSP00000495173