An immune basis for malaria protection by the sickle cell trait.
about
How malaria has affected the human genome and what human genetics can teach us about malariaBiochemical and immunological mechanisms by which sickle cell trait protects against malariaMutations in the MESP2 gene cause spondylothoracic dysostosis/Jarcho-Levin syndromeSickle cell anaemia and malariaGlobal distribution of the sickle cell gene and geographical confirmation of the malaria hypothesisThe impact of malaria parasitism: from corpuscles to communitiesImpaired cytoadherence of Plasmodium falciparum-infected erythrocytes containing sickle hemoglobinHemoglobinopathies: slicing the Gordian knot of Plasmodium falciparum malaria pathogenesisHeritability of malaria in Africa"Asymptomatic" Malaria: A Chronic and Debilitating Infection That Should Be TreatedThe influence of host genetics on erythrocytes and malaria infection: is there therapeutic potential?Online biomedical resources for malaria-related red cell disordersAbnormal PfEMP1/knob display on Plasmodium falciparum-infected erythrocytes containing hemoglobin variants: fresh insights into malaria pathogenesis and protectionAdvances in genetics and genomics: use and limitations in achieving malaria elimination goalsExtensive genomic variability of knops blood group polymorphisms is associated with sickle cell disease in AfricaHaplotype association between haptoglobin (Hp2) and Hp promoter SNP (A-61C) may explain previous controversy of haptoglobin and malaria protection.Haemoglobin C and S role in acquired immunity against Plasmodium falciparum malaria.Evidence for over-dispersion in the distribution of clinical malaria episodes in children.The quantity and quality of African children's IgG responses to merozoite surface antigens reflect protection against Plasmodium falciparum malariaHaptoglobin and sickle cell polymorphisms and risk of active trachoma in Gambian children.Transforming growth factor beta 2 and heme oxygenase 1 genes are risk factors for the cerebral malaria syndrome in Angolan children.Malaria parasites and red cell variants: when a house is not a home.A role for fetal hemoglobin and maternal immune IgG in infant resistance to Plasmodium falciparum malaria.Subclass responses and their half-lives for antibodies against EBA175 and PfRh2 in naturally acquired immunity against Plasmodium falciparum malaria.High number of previous Plasmodium falciparum clinical episodes increases risk of future episodes in a sub-group of individuals.Relationship between malaria incidence and IgG levels to Plasmodium falciparum merozoite antigens in Malian children: impact of hemoglobins S and C.Iron metabolism and malaria.Effects of age, hemoglobin type and parasite strain on IgG recognition of Plasmodium falciparum-infected erythrocytes in Malian children.Interethnic diversity of the CD209 (rs4804803) gene promoter polymorphism in African but not American sickle cell diseaseMechanistic Studies of the Negative Epistatic Malaria-protective Interaction Between Sickle Cell Trait and α(+)thalassemiaHemoglobin S and C heterozygosity enhances neither the magnitude nor breadth of antibody responses to a diverse array of Plasmodium falciparum antigens.Immunoglobulin response to Plasmodium falciparum RESA proteins in uncomplicated and severe malaria.Evidence for both innate and acquired mechanisms of protection from Plasmodium falciparum in children with sickle cell trait.Combining evidence of natural selection with association analysis increases power to detect malaria-resistance variants.Genetic determinants of anti-malarial acquired immunity in a large multi-centre studyHaemoglobinopathies and the clinical epidemiology of malaria: a systematic review and meta-analysis.Quantitative trait locus analysis of parasite density reveals that HbS gene carriage protects severe malaria patients against Plasmodium falciparum hyperparasitaemiaTranslocation of sickle cell erythrocyte microRNAs into Plasmodium falciparum inhibits parasite translation and contributes to malaria resistance.Hemoglobin C Trait Provides Protection From Clinical Falciparum Malaria in Malian Children.Heterogeneous alleles comprising G6PD deficiency trait in West Africa exert contrasting effects on two major clinical presentations of severe malaria.
P2860
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P2860
An immune basis for malaria protection by the sickle cell trait.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
An immune basis for malaria protection by the sickle cell trait
@nl
An immune basis for malaria protection by the sickle cell trait.
@ast
An immune basis for malaria protection by the sickle cell trait.
@en
An immune basis for malaria protection by the sickle cell trait.
@en-gb
type
label
An immune basis for malaria protection by the sickle cell trait
@nl
An immune basis for malaria protection by the sickle cell trait.
@ast
An immune basis for malaria protection by the sickle cell trait.
@en
An immune basis for malaria protection by the sickle cell trait.
@en-gb
altLabel
An Immune Basis for Malaria Protection by the Sickle Cell Trait
@en
prefLabel
An immune basis for malaria protection by the sickle cell trait
@nl
An immune basis for malaria protection by the sickle cell trait.
@ast
An immune basis for malaria protection by the sickle cell trait.
@en
An immune basis for malaria protection by the sickle cell trait.
@en-gb
P2093
P2860
P50
P3181
P1433
P1476
An immune basis for malaria protection by the sickle cell trait.
@en
P2093
David J Roberts
David J Weatherall
Moses Kortok
Neal D Alexander
Sammy Wambua
Tabitha W Mwangi
P2860
P3181
P356
10.1371/JOURNAL.PMED.0020128
P407
P577
2005-05-31T00:00:00Z