Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer - Wikidata - awgldk - TriplyDB

Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer

Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer

http://www.wikidata.org/entity/Q21144952

about

The common variant rs4444235 near BMP4 confers genetic susceptibility of colorectal cancer: an updated meta-analysis based on a comprehensive statistical strategy Phenotypic and tumor molecular characterization of colorectal cancer in relation to a susceptibility SMAD7 variant associated with survival Manipulation of DNA Repair Proficiency in Mouse Models of Colorectal Cancer Colitis-associated colon cancer: Is it in your genes?Genetic variations in colorectal cancer risk and clinical outcome Colorectal cancer: A review of the genome-wide association studies in the kingdom of Saudi Arabia Genetic Variants That Predispose to DNA Double-Strand Breaks in Lymphocytes From a Subset of Patients With Familial Colorectal Carcinomas Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.Functional annotation of putative regulatory elements at cancer susceptibility Loci The TERT variant rs2736100 is associated with colorectal cancer risk Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study.Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study.Association of Caucasian-identified variants with colorectal cancer risk in Singapore Chinese.Meta-analysis of the rs4779584 polymorphism and colorectal cancer risk.In silico pathway analysis and tissue specific cis-eQTL for colorectal cancer GWAS risk variants.Estimating the heritability of colorectal cancer.Colorectal polyp model established by transplacental BMP4 RNAi.Single nucleotide polymorphisms associated with colorectal cancer susceptibility and loss of heterozygosity in a Taiwanese population.A colorectal cancer susceptibility new variant at 4q26 in the Spanish population identified by genome-wide association analysis.Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis Genetic polymorphisms in MicroRNA-related genes as predictors of clinical outcomes in colorectal adenocarcinoma patients.Shared and independent colorectal cancer risk alleles in TGFβ-related genes in African and European Americans Early-onset colorectal cancer: a sporadic or inherited disease?The SNP rs961253 in 20p12.3 is associated with colorectal cancer risk: a case-control study and a meta-analysis of the published literature Pooled sample-based GWAS: a cost-effective alternative for identifying colorectal and prostate cancer risk variants in the Polish population.Genome-wide search for gene-gene interactions in colorectal cancer.Clinical application of genetics in management of colorectal cancer.Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci A colorectal cancer genome-wide association study in a Spanish cohort identifies two variants associated with colorectal cancer risk at 1p33 and 8p12.Positional mapping and candidate gene analysis of the mouse Ccs3 locus that regulates differential susceptibility to carcinogen-induced colorectal cancer.A novel colorectal cancer risk locus at 4q32.2 identified from an international genome-wide association study.Germline Mutations in the Polyposis-Associated Genes BMPR1A, SMAD4, PTEN, MUTYH and GREM1 Are Not Common in Individuals with Serrated Polyposis Syndrome.Fine-mapping of colorectal cancer susceptibility loci at 8q23.3, 16q22.1 and 19q13.11: refinement of association signals and use of in silico analysis to suggest functional variation and unexpected candidate target genes.Joint effects of colorectal cancer susceptibility loci, circulating 25-hydroxyvitamin D and risk of colorectal cancer.Germline variation in colorectal risk Loci does not influence treatment effect or survival in metastatic colorectal cancer.The MLH1 c.1852_1853delinsGC (p.K618A) variant in colorectal cancer: genetic association study in 18,723 individuals Candidate colorectal cancer predisposing gene variants in Chinese early-onset and familial cases.Multiple functional risk variants in a SMAD7 enhancer implicate a colorectal cancer risk haplotype.

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Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer

http://www.wikidata.org/entity/Q21144952

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2011 nî lūn-bûn

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Multiple common susceptibility ...... itability of colorectal cancer

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Multiple common susceptibility ...... itability of colorectal cancer

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Multiple common susceptibility ...... itability of colorectal cancer

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Multiple common susceptibility ...... itability of colorectal cancer

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Multiple common susceptibility ...... itability of colorectal cancer

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Multiple common susceptibility ...... itability of colorectal cancer

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Multiple common susceptibility ...... itability of colorectal cancer

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Multiple common susceptibility ...... itability of colorectal cancer

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Multiple common susceptibility ...... itability of colorectal cancer

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Multiple common susceptibility ...... itability of colorectal cancer

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JOURNAL.PGEN.1002105

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Multiple common susceptibility ...... itability of colorectal cancer

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Amy Lloyd

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Angela M Jones

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Bianca Olver

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Bryan Howie

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Ceres Fernandez-Rozadilla

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Clara Ruiz-Ponte

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David Conti

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David Duggan

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David J Kerr

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Ella Barclay

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P2860

Quantifying heterogeneity in a meta-analysis

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

Rare variants create synthetic genome-wide associations

Synthetic associations created by rare variants do not explain most GWAS results.

An ancestral Ashkenazi haplotype at the HMPS/CRAC1 locus on 15q13-q14 is associated with hereditary mixed polyposis syndrome

IRF4 variants have age-specific effects on nevus count and predispose to melanoma.

Genetics of coeliac disease.

A systematic review and meta-analysis of familial colorectal cancer risk.

Cetuximab therapy in first-line metastatic colorectal cancer and intermittent palliative chemotherapy: review of the COIN trial.

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e1002105

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10.1371/JOURNAL.PGEN.1002105

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6

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7

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Angel Carracedo

Steven Gallinger

Richard Houlston

Evropi Theodoratou

Jonathan Marchini

Malcolm G. Dunlop

Antoni Castells

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2011-06-01T00:00:00Z

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51203151

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21655089

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colorectal cancer

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3107194

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