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CUL1:SKP1:SKP2BTRC:CUL1:SKP1CUL1:FBXW11:SKP1SKP1:CUL1:RBX1:FBXL7SKP1:CUL1:RBX1:FBXL18FBXW7:SKP1:CUL1:RBX1FBXW7 WD mutants:SKP1:CUL1:RBX1CD4:Vpu:beta-TrCP_1:Skp1 complexVpu:beta-TrCP1:Skp1 complexFBXW7alpha:SKP1:CUL1:RBX1SCF(SKP2) complexSCF-beta-TRCPSCF E3 ubiquitin ligaseBTRC:CUL1:RBX1:SKP1NEDD8-CRL1 E3 ligase complexSKP1:CUL1:FBXL5Formation of the SCF-FBXL7 complexThe Vpu:CD4:beta-TrCP complex recruits SKP1CUL1; SKP1; FBXL5 bind
P527
P688
Fbx7 functions in the SCF complex regulating Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich regionThe novel human DNA helicase hFBH1 is an F-box proteinRegulation of p27 degradation and S-phase progression by Ro52 RING finger proteinPolycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targetsSCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterningPriming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrateStructure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligaseSCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myelomaThe SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplicationFBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradationSCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradationPhosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7A Competitive binding mechanism between Skp1 and exportin 1 (CRM1) controls the localization of a subset of F-box proteinsMultiple isoforms of beta-TrCP display differential activities in the regulation of Wnt signalingThe modular structure of SIP facilitates its role in stabilizing multiprotein assembliesThe pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCFFBXW7 function.
P921
Q50250831-2932D74C-2AE0-4AB0-AE53-13B240387A87Q50251126-058383E3-0AD5-4FD0-B59C-6AB5A898FFAEQ50251127-C3C57FC9-F272-4903-8D9E-A1BE2BDEBCD9Q50251187-0285BD28-65AB-4075-9430-65D6239229DCQ50251193-E80DEF83-F62C-4BB8-89A9-8262162F5195Q50256044-567743A6-2F08-4B04-9CE7-95774F79404DQ50256067-393F034B-8D8E-4A72-AF71-179F3AB8D195Q50256712-A6A694C8-022B-44FF-B51D-6E63A4AC5C10Q50256715-3E89762B-5E72-4E47-BDAA-5E411D4973A1Q50258446-95C6155C-A8C9-4340-9542-E0AA501337A7Q50258456-9D64D949-3E76-4EA9-A25D-DC040AFD67DCQ50259865-D9DC6260-6D45-4446-BAF6-01A8ACDD2540Q50260147-ECA621D4-7D9B-4E25-BD01-1E11DD6C2C45Q50262703-1408A0FA-E7E9-488A-9C37-56995E2DCFE5Q50269315-725DF7D1-D821-405C-A83C-F7207D255BF4Q50274610-A53C6580-7B06-425C-9834-A6D309AAB46FQ50286174-7356E767-0767-465E-B35F-CCCF641AF78BQ50289452-7F7E8F8D-2BC4-4E6D-84C0-ED46CCC31C0CQ50299637-7CADD445-A123-4BE2-8C97-A84FBE217B77
P527
Q24293185-F51A82E3-486E-4857-B8AA-7EC85EEF3961Q24294566-7BE0AA3E-AFE5-4ED9-B395-8600D78E0D41Q24298491-AF214481-E45E-423F-A56F-07CDC0195BD4Q24301123-1FA4C044-50EE-46CA-AACF-109AD775ABFFQ24302375-FCA0AAA3-E995-4F63-B1DD-C42F154245D7Q24302459-2222326D-9434-4617-8317-6161FF697842Q24304915-9404CC90-295F-49FA-BE82-2691C47AEF10Q24306203-EFB0AD3D-8C23-4366-BCDC-0F4CABBDEBA0Q24306820-DDC9A3E5-E309-4831-935C-B6EAF68566F7Q24310354-E20996DA-9D52-4E60-B116-2D2740FB9C20Q24314570-C549670E-C091-4184-B937-B3E945964C46Q24315972-7C0080C8-6BC7-43C6-BD29-A12105A947D9Q24337147-D1CCC606-DA9A-4202-B2EF-A74F95C78F73Q24337643-9AC89A73-D7AB-47D3-8721-5C180EE0B27CQ28116106-C26D3042-1EEE-4332-A5E0-D5F5E66D507DQ28119010-E0A48EF1-D928-4B0A-AE24-184C0F6083A0Q28910203-A667A5AE-7E8D-4A17-9863-86AD95EFB10BQ38779048-84F0AFD4-B94D-4D2A-A89C-B11A250FA55F
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
proteinë
@sq
proteïne in S-phase kinase associated protein 1
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
S-phase kinase associated protein 1
@en
S-phase kinase associated protein 1
@nl
type
label
S-phase kinase associated protein 1
@en
S-phase kinase associated protein 1
@nl
altLabel
OCP-2
@en
OCP-II
@en
RNA polymerase II elongation factor-like protein OCP2
@en
RNA polymerase II elongation factor-like protein
@en
S-phase kinase-associated protein 1
@en
SIII
@en
SKP1
@en
cyclin A/CDK2-associated p19
@en
cyclin-A/CDK2-associated protein p19
@en
organ of Corti protein 2
@en
prefLabel
S-phase kinase associated protein 1
@en
S-phase kinase associated protein 1
@nl
P361
P638
P680
P681
P682
P705
P352
P279
P31
P352
P361
P637
P638
P680
P681
P682
P702
P703
P705
ENSP00000231487
ENSP00000331708
ENSP00000428962
ENSP00000429415
ENSP00000429472
ENSP00000429686
ENSP00000429961
ENSP00000429995
ENSP00000429996
ENSP00000430885