A new paramagnetically shifted imaging probe for MRI.Direct and selective tagging of cysteine residues in peptides and proteins with 4-nitropyridyl lanthanide complexes.Towards rational design of fast water-exchanging Gd(dota-like) contrast agents? Importance of the M/m ratio.Structural, luminescence, and NMR studies of the reversible binding of acetate, lactate, citrate, and selected amino acids to chiral diaqua ytterbium, gadolinium, and europium complexes.Synthesis, stereocontrol and structural studies of highly luminescent chiral tris-amidepyridyl-triazacyclononane lanthanide complexes.Ternary complexes between cationic GdIII chelates and anionic metabolites in aqueous solution: an NMR relaxometric study.Magnetic resonance and optical imaging probes for NMDA receptors on the cell surface of neurons: synthesis and evaluation in cellulo.Critical design issues in the targeted molecular imaging of cell surface receptors.Excitement in f block: structure, dynamics and function of nine-coordinate chiral lanthanide complexes in aqueous media.Approaching 'Kit-Type' Labelling with (68)Ga: The DATA Chelators.Glycoconjugates of gadolinium complexes for MRI applications.Synthesis and characterisation of dimeric eight-coordinate lanthanide(III) complexes of a macrocyclic tribenzylphosphinate ligand.On the role of the counter-ion in defining water structure and dynamics: order, structure and dynamics in hydrophilic and hydrophobic gadolinium salt complexes.19F NMR based pH probes: lanthanide(III) complexes with pH-sensitive chemical shifts.NMR and chiroptical examination of the diastereoisomers of (S)-Eu-EOB-DTPA.Two-photon absorption and photoluminescence of europium based emissive probes for bioactive systems.Variation of water exchange dynamics with ligand structure and stereochemistry in lanthanide complexes based on 1,4-diazepine derivatives.Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: applications in ratiometric oxygen sensing in vitro and in regioselective cell killing.Anion binding in water at lanthanide centres: from structure and selectivity to signalling and sensing.Isostructural series of nine-coordinate chiral lanthanide complexes based on triazacyclononane.A bright and responsive europium probe for determination of pH change within the endoplasmic reticulum of living cells.Optimizing the high-field relaxivity by self-assembling of macrocyclic Gd(III) complexes.Simultaneous Triple Imaging with Two PARASHIFT Probes: Encoding Anatomical, pH and Temperature Information using Magnetic Resonance Shift Imaging.The mechanism of cell uptake for luminescent lanthanide optical probes: the role of macropinocytosis and the effect of enhanced membrane permeability on compartmentalisation.Development of responsive lanthanide probes for cellular applications.Lanthanide complexes as chiral probes exploiting circularly polarized luminescence.EuroTracker® dyes: design, synthesis, structure and photophysical properties of very bright europium complexes and their use in bioassays and cellular optical imaging.Equilibrium, Kinetic and Structural Properties of Gallium(III) and Some Divalent Metal Complexes Formed with the New DATAm and DATA5m Ligands.Wavelength-dependent optoacoustic imaging probes for NMDA receptor visualisation.Microscopic visualization of metabotropic glutamate receptors on the surface of living cells using bifunctional magnetic resonance imaging probesInduced Europium Circularly Polarized Luminescence Monitors Reversible Drug Binding to Native α1 -Acid Glycoprotein.Comparative in vitro studies of MR imaging probes for metabotropic glutamate subtype-5 receptor targeting.Responsive, Water-Soluble Europium(III) Luminescent Probes.Live cell imaging of lysosomal pH changes with pH responsive ratiometric lanthanide probes.Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells.Strategies to enhance signal intensity with paramagnetic fluorine-labelled lanthanide complexes as probes for 19F magnetic resonance.Cell-penetrating metal complex optical probes: targeted and responsive systems based on lanthanide luminescence.The nature of the sensitiser substituent determines quenching sensitivity and protein affinity and influences the design of emissive lanthanide complexes as optical probes for intracellular use.Electromagnetic susceptibility anisotropy and its importance for paramagnetic NMR and optical spectroscopy in lanthanide coordination chemistry.Identification of emissive lanthanide complexes suitable for cellular imaging that resist quenching by endogenous anti-oxidants.
P50
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P50
description
Professor David Parker FRS, Department of Chemistry, Durham University
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David Parker
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David Parker
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David Parker
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Дэвид Парк
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David Parker
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David Parker
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David Parker
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David Parker
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David Parker
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Дэвид Парк
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David Parker
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David Parker
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David Parker
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David Parker
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David Parker
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David Parker
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Дэвид Парк
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P166
P214
P1053
F-5294-2012
P106
P18
P2070
david-parker-12045
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0000 0000 3132 9926
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P3829
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0000-0001-5281-5146
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1956-07-30T00:00:00Z
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lccn-n95091503