about
P527
P688
ALS2CL, a novel ALS2-interactor, modulates ALS2-mediated endosome dynamicsHomo-oligomerization of ALS2 through its unique carboxyl-terminal regions is essential for the ALS2-associated Rab5 guanine nucleotide exchange activity and its regulatory function on endosome traffickingA novel somatodendritic marker defined by a peptide derived from the ALS2 proteinALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamicsALS2/Alsin regulates Rac-PAK signaling and neurite outgrowthAlsin is partially associated with centrosome in human cellsThe first ALS2 missense mutation associated with JPLS reveals new aspects of alsin biological functionA Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death.
P921
Q24293687-2411446A-BDB5-4A82-B0FF-42459FC50BB1Q24298929-2E2F795A-DD34-4426-9584-9131C1180B32Q24304299-33F95639-6D1C-4C96-8267-44C5499C7F6FQ24306668-23B0FC5F-4061-45DF-8CDB-71DA722E97A7Q24310305-7A2C23D7-87DC-43FB-B014-A965DE1A25E1Q24313283-14135F0B-7061-4623-A6A7-986530BDB0B2Q24323538-212AEB18-E25E-4774-8B1E-8D23312DFEC5Q40484912-075D527F-3356-4E3C-83E2-4E1A7653EC2A
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
proteinë
@sq
proteïne in ALS2, alsin Rho guanine nucleotide exchange factor
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
Alsin Rho guanine nucleotide exchange factor ALS2
@en
Alsin Rho guanine nucleotide exchange factor ALS2
@nl
type
label
Alsin Rho guanine nucleotide exchange factor ALS2
@en
Alsin Rho guanine nucleotide exchange factor ALS2
@nl
altLabel
ALS2
@en
ALS2, alsin Rho guanine nucleotide exchange factor
@en
alsin
@en
amyotrophic lateral sclerosis 2 (juvenile)
@en
amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein
@en
amyotrophic lateral sclerosis 2 protein
@en
prefLabel
Alsin Rho guanine nucleotide exchange factor ALS2
@en
Alsin Rho guanine nucleotide exchange factor ALS2
@nl
P361
P527
P637
P680
P681
P682
P705
P352
P637
P31
P352
P361
P637
NP_001129217
XP_006712717
XP_006712718
XP_016860058
XP_016860059
XP_016860061
XP_024308792
XP_024308793
P680
P681
P682
P702
P703
P705
ENSP00000264276
ENSP00000386384
ENSP00000386948
ENSP00000403832
ENSP00000429223