Haploinsufficient Bmp4 ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressure
about
Compound developmental eye disorders following inactivation of TGFbeta signaling in neural-crest stem cells.X-linked megalocornea caused by mutations in CHRDL1 identifies an essential role for ventroptin in anterior segment developmentSMOC1 is essential for ocular and limb development in humans and miceExtracellular matrix in the trabecular meshwork: intraocular pressure regulation and dysregulation in glaucomaProgenitors for the corneal endothelium and trabecular meshwork: a potential source for personalized stem cell therapy in corneal endothelial diseases and glaucomaLoss of the BMP antagonist, SMOC-1, causes Ophthalmo-acromelic (Waardenburg Anophthalmia) syndrome in humans and miceCyp1b1 mediates periostin regulation of trabecular meshwork development by suppression of oxidative stressNinjurin1 mediates macrophage-induced programmed cell death during early ocular developmentOcular abnormalities in mice lacking the immunoglobulin superfamily member CdoLmx1b is required for murine trabecular meshwork formation and for maintenance of corneal transparencyNotch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eyeThe level of BMP4 signaling is critical for the regulation of distinct T-box gene expression domains and growth along the dorso-ventral axis of the optic cupTranscriptional regulation of bone morphogenetic protein 4 by tumor necrosis factor and its relationship with age-related macular degeneration.pitx2 Deficiency results in abnormal ocular and craniofacial development in zebrafishOver-expression of BMP4 inhibits experimental choroidal neovascularization by modulating VEGF and MMP-9.Activation of BMP-Smad1/5/8 signaling promotes survival of retinal ganglion cells after damage in vivoPlatelet-derived growth factor over-expression in retinal progenitors results in abnormal retinal vessel formation.Reduced TFAP2A function causes variable optic fissure closure and retinal defects and sensitizes eye development to mutations in other morphogenetic regulatorsAnterior segment dysgenesis and early-onset glaucoma in nee mice with mutation of Sh3pxd2bMatrix GLA protein function in human trabecular meshwork cells: inhibition of BMP2-induced calcification process.BMP4 loss-of-function mutations in developmental eye disorders including SHORT syndromeNiche regulation of corneal epithelial stem cells at the limbus.Eye development genes and known syndromesAnterior eye development and ocular mesenchyme: new insights from mouse models and human diseasesDetection of differentially expressed glycogenes in trabecular meshwork of eyes with primary open-angle glaucoma.Common TGFβ2, BMP4, and FOXC1 variants are not associated with primary open-angle glaucoma.Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities.Mutations in BMP4 cause eye, brain, and digit developmental anomalies: overlap between the BMP4 and hedgehog signaling pathways.A novel mechanistic spectrum underlies glaucoma-associated chromosome 6p25 copy number variation.Molecular and developmental mechanisms of anterior segment dysgenesis.An essential role for Radar (Gdf6a) in inducing dorsal fate in the zebrafish retina.Dexamethasone induces cross-linked actin networks in trabecular meshwork cells through noncanonical wnt signalingChromosomal rearrangements and novel genes in disorders of eye development, cataract and glaucoma.YBR/EiJ mice: a new model of glaucoma caused by genes on chromosomes 4 and 17.Heparan sulfate deficiency leads to Peters anomaly in mice by disturbing neural crest TGF-beta2 signaling.Noggin producing, MyoD-positive cells are crucial for eye development.Signaling "cross-talk" is integrated by transcription factors in the development of the anterior segment in the eye.Cleavages within the prodomain direct intracellular trafficking and degradation of mature bone morphogenetic protein-4.Conserved genetic pathways associated with microphthalmia, anophthalmia, and coloboma.A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of Tsc1 disrupts ciliary body and iris development
P2860
Q21146755-EB8130C5-2BFD-4F11-8471-37982AEC65D3Q24303793-128FFA3F-7674-4C1E-8A77-5EFA4D7533B8Q24322076-2CB49AC0-29CE-420F-98FD-99E2303A7BA6Q26851287-32683056-E731-4CAB-B901-2B28AEEBCB35Q27001064-7ADE092E-69D8-401C-ADDB-693A28E3773BQ27339890-4E3106AE-1825-426D-93F6-01081F65B2ACQ28507083-79F5A8F2-05A6-45FF-8B6B-9EFCF9584FF0Q28590942-4FD3984D-4D53-4AE7-9BC0-C9454C1C88B4Q28591959-3A10AFEF-C9BA-4FDE-8423-F1F5E1B38FF4Q28592334-C210700F-643D-40A0-B45D-9BEA583EA01AQ28593168-7F0493EC-CE76-42A1-B83D-5F0776B006FDQ33266825-17D9DBCC-322A-4F03-81B3-6A4EA74A1602Q33848783-704B085C-93E3-480C-BE2F-F4D4F57D3A79Q34150038-3AAD2C77-D9CA-4508-8AA9-BA17FB397826Q34185266-C5B85675-29BE-4CB1-AF63-89941D7127EEQ34305677-4CAC3844-8CF6-4905-96A3-88219B98B4FDQ34374175-ECDFFAC5-A03E-4ED2-9285-4B31190B8BD5Q34876963-26FCC701-1E42-4409-A5EF-449E44D9F86BQ34936970-8583047C-EF49-4D2E-8668-A03488526EE1Q35070274-EBB6D545-82BE-4873-BE80-C5543DF165F8Q35228402-3236919F-9FE0-4CCD-871F-38AD0C06BB86Q35302474-DEA0F1A1-F294-4D08-B8F9-79BEBE302F1CQ35573283-5E25B380-D60D-4A03-81A2-A206C4AC625DQ35731050-B596B058-8CDA-407F-A254-16CE3327E844Q35925346-D8BD36C0-07FD-4DF5-99FC-44B10944E104Q36051706-CCC36E55-A3B1-4E0D-AEF8-471546B47A11Q36236937-5FF80558-7265-4040-BCF8-925D942BC7FAQ36719098-0A7489A5-F943-4796-AFC0-505C992D14B1Q36948282-2822E888-384A-4588-BDAC-8F883887DD63Q36959904-C504E5CC-3B29-46C8-BB08-13AA55CDD130Q37114779-C4D93C8B-3ED0-47DF-8233-A6600EFA8DA3Q37214888-FA21E182-357C-4A00-B661-19B3A28F9DF7Q37220091-FC7A5CC0-47D0-4BB3-B8F0-7742F57E18F9Q37224623-0C7E7A88-7D72-42F6-8A4E-193962A864B1Q37241414-C4273C19-0163-4530-9F91-EEB181FD1038Q37439322-8DCC67C8-0D88-4537-BE70-AD1C2DC2D2CDQ37558392-4E01FBE3-71D2-4BEA-A134-3D9E819109A6Q37595180-C0A47DCA-5725-49C0-B9CB-675C14150E9EQ38517281-8757A6E4-C610-4295-B214-0D734875D708Q38751824-7883ABA0-C257-48D9-8429-CF784B0AED0D
P2860
Haploinsufficient Bmp4 ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressure
description
2001 nî lūn-bûn
@nan
2001 թուականին հրատարակուած գիտական յօդուած
@hyw
2001 թվականին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Haploinsufficient Bmp4 ocular ...... elevated intraocular pressure
@ast
Haploinsufficient Bmp4 ocular ...... elevated intraocular pressure
@en
Haploinsufficient Bmp4 ocular ...... elevated intraocular pressure
@en-gb
Haploinsufficient Bmp4 ocular ...... elevated intraocular pressure
@nl
type
label
Haploinsufficient Bmp4 ocular ...... elevated intraocular pressure
@ast
Haploinsufficient Bmp4 ocular ...... elevated intraocular pressure
@en
Haploinsufficient Bmp4 ocular ...... elevated intraocular pressure
@en-gb
Haploinsufficient Bmp4 ocular ...... elevated intraocular pressure
@nl
prefLabel
Haploinsufficient Bmp4 ocular ...... elevated intraocular pressure
@ast
Haploinsufficient Bmp4 ocular ...... elevated intraocular pressure
@en
Haploinsufficient Bmp4 ocular ...... elevated intraocular pressure
@en-gb
Haploinsufficient Bmp4 ocular ...... elevated intraocular pressure
@nl
P2093
P2860
P3181
P356
P1433
P1476
Haploinsufficient Bmp4 ocular ...... elevated intraocular pressure
@en
P2093
A Zabaleta
J E Martin
M L Davisson
O V Savinova
P2860
P2888
P3181
P356
10.1186/1471-2156-2-18
P407
P577
2001-01-01T00:00:00Z
P5875
P6179
1040507098