about
P688
The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammationThe deubiquitinating enzyme CYLD controls apical docking of basal bodies in ciliated epithelial cellsCYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulinCaspase 8 inhibits programmed necrosis by processing CYLDCyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signalingRegulation of T cell development by the deubiquitinating enzyme CYLDcIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species productionUsp12 stabilizes the T-cell receptor complex at the cell surface during signalingSPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination.The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis.
P921
Q24296068-FE988744-A18D-48C9-AEE1-43C3C72CA6DAQ24302203-66FA866F-C623-4D9D-819F-2AF076960910Q24314876-6F55EBF1-7126-49ED-8D2A-111D816F8598Q28584927-D29C9D27-2242-4F0D-B619-819A50C0912BQ28588278-24C2611F-22DC-4F01-BEA1-E33315D758A1Q28588773-54EEB644-1184-4212-9734-D7279D1C9F58Q28591258-251F074C-0431-406E-B3B1-0A50ACCCEB1DQ28941247-1E1D9304-0474-4753-B6D8-702E564FE8ACQ41001480-04992A44-58D0-4895-B248-FAEB4EE40E63Q47141410-63E2AB0D-2D45-435B-8E68-3024FD7F1AA5Q48326227-A93A8A58-68C3-4C27-A445-F31A436211EB
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in CYLD lysine 63 deubiquitinase
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
CYLD lysine 63 deubiquitinase
@en
type
label
CYLD lysine 63 deubiquitinase
@en
altLabel
Cyld
@en
cylindromatosis (turban tumor syndrome)
@en
deubiquitinating enzyme CYLD
@en
ubiquitin carboxyl-terminal hydrolase CYLD
@en
ubiquitin thioesterase CYLD
@en
ubiquitin thiolesterase CYLD
@en
ubiquitin-specific-processing protease CYLD
@en
prefLabel
CYLD lysine 63 deubiquitinase
@en
P361
P527
P637
P680
P681
P682
P705
P352
P637
P31
P352
P527
P637
NP_001121642
NP_001121643
NP_001263208
XP_006531477
XP_006531478
XP_006531479
XP_006531480
XP_006531481
XP_006531482
P680
P681
P682
P702
P703
P705
ENSMUSP00000039834
ENSMUSP00000096119
ENSMUSP00000105254
ENSMUSP00000147426
ENSMUSP00000147654
ENSMUSP00000147904
ENSMUSP00000148037