Evolutionarily divergent, unstable filamentous actin is essential for gliding motility in apicomplexan parasites
about
Dense granule trafficking in Toxoplasma gondii requires a unique class 27 myosin and actin filamentsComparative Plasmodium gene overexpression reveals distinct perturbation of sporozoite transmission by profilin.Disassembly activity of actin-depolymerizing factor (ADF) is associated with distinct cellular processes in apicomplexan parasites.Spatial localisation of actin filaments across developmental stages of the malaria parasiteThe Actin Filament-Binding Protein Coronin Regulates Motility in Plasmodium Sporozoites.The toxoplasma Acto-MyoA motor complex is important but not essential for gliding motility and host cell invasionStructural differences explain diverse functions of Plasmodium actinsDisruption of TgPHIL1 alters specific parameters of Toxoplasma gondii motility measured in a quantitative, three-dimensional live motility assayThe lasso segment is required for functional dimerization of the Plasmodium formin 1 FH2 domainNew cell motility model observed in parasitic cnidarian Sphaerospora molnari (Myxozoa:Myxosporea) blood stages in fish.Pivotal and distinct role for Plasmodium actin capping protein alpha during blood infection of the malaria parasiteA mechanism for actin filament severing by malaria parasite actin depolymerizing factor 1 via a low affinity binding interfacePlasmodium falciparum coronin organizes arrays of parallel actin filaments potentially guiding directional motility in invasive malaria parasitesDirect measurement of cortical force generation and polarization in a living parasiteTargeted proteomic dissection of Toxoplasma cytoskeleton sub-compartments using MORN1.The unusual dynamics of parasite actin result from isodesmic polymerization.Calcium-dependent phosphorylation alters class XIVa myosin function in the protozoan parasite Toxoplasma gondiiPlasmodium actin is incompletely folded by heterologous protein-folding machinery and likely requires the native Plasmodium chaperonin complex to enter a mature functional state.A unique profilin-actin interface is important for malaria parasite motilityActin-mediated plasma membrane plasticity of the intracellular parasite Theileria annulata.Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites.Comparative transcriptomics reveals striking similarities between the bovine and feline isolates of Tritrichomonas foetus: consequences for in silico drug-target identification.Host cell invasion by apicomplexan parasites: the junction conundrumMolecular characterization of Toxoplasma gondii formin 3, an actin nucleator dispensable for tachyzoite growth and motility.Toxoplasma gondii profilin acts primarily to sequester G-actin while formins efficiently nucleate actin filament formation in vitro.Lytic Cycle of Toxoplasma gondii: 15 Years Later.Calmodulin-like proteins localized to the conoid regulate motility and cell invasion by Toxoplasma gondiiCofilin-induced cooperative conformational changes of actin subunits revealed using cofilin-actin fusion proteinConditional genome engineering in Toxoplasma gondii uncovers alternative invasion mechanisms.Synthetic chondramide A analogues stabilize filamentous actin and block invasion by Toxoplasma gondii.Reassessing the mechanics of parasite motility and host-cell invasion.Toxoplasma aldolase is required for metabolism but dispensable for host-cell invasionToxoplasma gondii F-actin forms an extensive filamentous network required for material exchange and parasite maturationHolding back the microfilament--structural insights into actin and the actin-monomer-binding proteins of apicomplexan parasites.The apicomplexan glideosome and adhesins - Structures and function.Towards a molecular understanding of the apicomplexan actin motor: on a road to novel targets for malaria remedies?Comparative proteomic analysis of different Toxoplasma gondii genotypes by two-dimensional fluorescence difference gel electrophoresis combined with mass spectrometry.Plasmodium Sporozoite Biology.Gliding motility powers invasion and egress in Apicomplexa.Functional insights into pathogen biology from 3D electron microscopy.
P2860
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P2860
Evolutionarily divergent, unstable filamentous actin is essential for gliding motility in apicomplexan parasites
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Evolutionarily divergent, unst ...... lity in apicomplexan parasites
@ast
Evolutionarily divergent, unst ...... lity in apicomplexan parasites
@en
Evolutionarily divergent, unst ...... lity in apicomplexan parasites
@en-gb
Evolutionarily divergent, unst ...... lity in apicomplexan parasites
@nl
type
label
Evolutionarily divergent, unst ...... lity in apicomplexan parasites
@ast
Evolutionarily divergent, unst ...... lity in apicomplexan parasites
@en
Evolutionarily divergent, unst ...... lity in apicomplexan parasites
@en-gb
Evolutionarily divergent, unst ...... lity in apicomplexan parasites
@nl
altLabel
Evolutionarily Divergent, Unst ...... lity in Apicomplexan Parasites
@en
prefLabel
Evolutionarily divergent, unst ...... lity in apicomplexan parasites
@ast
Evolutionarily divergent, unst ...... lity in apicomplexan parasites
@en
Evolutionarily divergent, unst ...... lity in apicomplexan parasites
@en-gb
Evolutionarily divergent, unst ...... lity in apicomplexan parasites
@nl
P2093
P2860
P3181
P1433
P1476
Evolutionarily divergent, unst ...... lity in apicomplexan parasites
@en
P2093
Karthikeyan Diraviyam
Keliang Tang
Kristen M Skillman
P2860
P304
P3181
P356
10.1371/JOURNAL.PPAT.1002280
P407
P577
2011-10-01T00:00:00Z