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The use of nonhuman primate models in HIV vaccine development

The use of nonhuman primate models in HIV vaccine development

http://www.wikidata.org/entity/Q21563403

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HSV-2: in pursuit of a vaccine HIV vaccine development: strategies for preclinical and clinical investigation Mucosal B Cells Are Associated with Delayed SIV Acquisition in Vaccinated Female but Not Male Rhesus Macaques Following SIVmac251 Rectal Challenge Surrogates of protection in repeated low-dose challenge experiments.Controlling the HIV/AIDS epidemic: current status and global challenges Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein.Use of nonhuman primate models to develop mucosal AIDS vaccines.New directions for HIV vaccine development from animal models.Update on animal models for HIV research.Phenotypes and distribution of mucosal memory B-cell populations in the SIV/SHIV rhesus macaque model.Antibody-mediated protection against mucosal simian-human immunodeficiency virus challenge of macaques immunized with alphavirus replicon particles and boosted with trimeric envelope glycoprotein in MF59 adjuvant International multicenter study to assess a panel of reference materials for quantification of simian immunodeficiency virus RNA in plasma Variability of bio-clinical parameters in Chinese-origin Rhesus macaques infected with simian immunodeficiency virus: a nonhuman primate AIDS model IIIa deleted adenovirus as a single-cycle genome replicating vector.Heterologous prime/boost immunizations of rhesus monkeys using chimpanzee adenovirus vectors Systems vaccinology.Antibody persistence and T-cell balance: two key factors confronting HIV vaccine development.Stem memory T cells (TSCM)-their role in cancer and HIV immunotherapies Overnight resting of PBMC changes functional signatures of antigen specific T- cell responses: impact for immune monitoring within clinical trials.Monkeying around with HIV vaccines: using rhesus macaques to define 'gatekeepers' for clinical trials.A longitudinal magnetization transfer imaging evaluation of brain injury in a macaque model of neuroAIDS Prime-boost vaccination with heterologous live vectors encoding SIV gag and multimeric HIV-1 gp160 protein: efficacy against repeated mucosal R5 clade C SHIV challenges.Analysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunization Low-dose penile SIVmac251 exposure of rhesus macaques infected with adenovirus type 5 (Ad5) and then immunized with a replication-defective Ad5-based SIV gag/pol/nef vaccine recapitulates the results of the phase IIb step trial of a similar HIV-1 va Inclusion of a CRF01_AE HIV envelope protein boost with a DNA/MVA prime-boost vaccine: Impact on humoral and cellular immunogenicity and viral load reduction after SHIV-E challenge.Association of MHC-I genotypes with disease progression in HIV/SIV infections.Association of major histocompatibility complex class I haplotypes with disease progression after simian immunodeficiency virus challenge in burmese rhesus macaques.NK and CD4+ T cell cooperative immune responses correlate with control of disease in a macaque simian immunodeficiency virus infection model.Mycobacterium tuberculosis infections in cynomolgus monkey transplant recipients and institution of a screening program for the prevention and control of tuberculosis Rhesus Macaque B-Cell Responses to an HIV-1 Trimer Vaccine Revealed by Unbiased Longitudinal Repertoire Analysis.Circumventing antivector immunity by using adenovirus-infected blood cells for repeated application of adenovirus-vectored vaccines: proof of concept in rhesus macaques.Vaccine Induction of Lymph Node-Resident Simian Immunodeficiency Virus Env-Specific T Follicular Helper Cells in Rhesus Macaques Mucosal transmissibility, disease induction and coreceptor switching of R5 SHIVSF162P3N molecular clones in rhesus macaques.Efficient mucosal transmissibility but limited pathogenicity of R5 SHIV SF162P3N in Chinese-origin rhesus macaques.Generation of lineage-related, mucosally transmissible subtype C R5 simian-human immunodeficiency viruses capable of AIDS development, induction of neurological disease, and coreceptor switching in rhesus macaques.Evaluation of Functional NK Cell Responses in Vaccinated and SIV-Infected Rhesus Macaques Antiretroviral therapy partly reverses the systemic and mucosal distribution of NK cell subsets that is altered by SIVmac₂₅₁ infection of macaques.HIV-specific CD8⁺ T-cell immunity in humanized bone marrow-liver-thymus mice Old world monkeys and new age science: the evolution of nonhuman primate systems virology.Simian immunodeficiency virus SIVrcm, a unique CCR2-tropic virus, selectively depletes memory CD4+ T cells in pigtailed macaques through expanded coreceptor usage in vivo.

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The use of nonhuman primate models in HIV vaccine development

http://www.wikidata.org/entity/Q21563403

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2008 nî lūn-bûn

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2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2008 թվականի օգոստոսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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The use of nonhuman primate models in HIV vaccine development

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The use of nonhuman primate models in HIV vaccine development

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Ann Duerr

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Cecilia Morgan

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Christopher Miller

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Harriet Robinson

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Jeffrey Lifson

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John Moore

http://www.w3.org/2001/XMLSchema#string

Jorge Flores

http://www.w3.org/2001/XMLSchema#string

Marta Marthas

http://www.w3.org/2001/XMLSchema#string

R Paul Johnson

http://www.w3.org/2001/XMLSchema#string

Ronald Desrosiers

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P2860

Protection by live, attenuated simian immunodeficiency virus against heterologous challenge.

Attenuation of simian immunodeficiency virus SIVmac239 infection by prophylactic immunization with dna and recombinant adenoviral vaccine vectors expressing Gag

Vaccine-induced cellular immune responses reduce plasma viral concentrations after repeated low-dose challenge with pathogenic simian immunodeficiency virus SIVmac239

Non-human primate models for AIDS vaccine research.

A call for replicating vector prime-protein boost strategies in HIV vaccine design.

Predictive value of primate models for AIDS.

T cell vaccines for microbial infections.

HIV vaccine design: insights from live attenuated SIV vaccines.

Progress and obstacles in the development of an AIDS vaccine.

Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity.

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Cecilia Cheng-Mayer

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David C Montefiori

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23168571

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18700814

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vaccine development

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2504486

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