about
P688
HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensingDifferential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element. Cross-talk between basic helix-loop-helix/per-Arnt-Sim homology transcription factorsHypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transitionMetallothionein-III induces HIF-1alpha-mediated VEGF expression in brain endothelial cellsThe survival effect of mitochondrial Higd-1a is associated with suppression of cytochrome C release and prevention of caspase activationTranscriptional activation of hypoxia-inducible factor-1alpha by HDAC4 and HDAC5 involves differential recruitment of p300 and FIH-1Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1Loss of PINK1 attenuates HIF-1α induction by preventing 4E-BP1-dependent switch in protein translation under hypoxiaSiah2-dependent concerted activity of HIF and FoxA2 regulates formation of neuroendocrine phenotype and neuroendocrine prostate tumorsA novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular developmentLoss of skeletal muscle HIF-1alpha results in altered exercise enduranceStructural integration in hypoxia-inducible factorsHypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domainsCellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alphaLoss of hepatocyte-nuclear-factor-1alpha impacts on adult mouse intestinal epithelial cell growth and cell lineages differentiationHypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survivalVhlh gene deletion induces Hif-1-mediated cell death in thymocytesCited2 is required for the proper formation of the hyaloid vasculature and for lens morphogenesisLack of hypoxia-inducible factor-1 alpha impairs midbrain neural precursor cells involving vascular endothelial growth factor signalingPro-apoptotic activity of inhibitory PAS domain protein (IPAS), a negative regulator of HIF-1, through binding to pro-survival Bcl-2 family proteinsImpaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alphaEnhanced bone regeneration associated with decreased apoptosis in mice with partial HIF-1alpha deficiencyHypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alphaDefective vascularization of HIF-1alpha-null embryos is not associated with VEGF deficiency but with mesenchymal cell deathIncreased activity of hypoxia-inducible factor 1 is associated with early embryonic lethality in Commd1 null miceDefective brain development in mice lacking the Hif-1alpha gene in neural cellsExpression of neural cell adhesion molecule (NCAM) during the first molar development in the mouseRSUME is implicated in HIF-1-induced VEGF-A production in pituitary tumour cellsAbnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1alpha -deficient chimeric mice.Hypoxia-inducible factor-1α protein negatively regulates load-induced bone formationHypoxia-inducible factors 1alpha and 2alpha regulate trophoblast differentiation.Induction of phosphoglycerate kinase 1 gene expression by hypoxia. Roles of Arnt and HIF1alphaIsoform-specific expression of hypoxia-inducible factor-1alpha during the late stages of mouse spermiogenesisMitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxiaHIF1A is essential for the development of the intermediate plexus of the retinal vasculatureRetinoic acid, hypoxia, and GATA factors cooperatively control the onset of fetal liver erythropoietin expression and erythropoietic differentiationHIF-1 alpha is required for solid tumor formation and embryonic vascularization.Molecular characterization of the murine Hif-1 alpha locusVEGFA is necessary for chondrocyte survival during bone developmentThe hypoxia-inducible microRNA cluster miR-199a∼214 targets myocardial PPARδ and impairs mitochondrial fatty acid oxidation
P921
Q24291102-0996B8E7-C09D-46B9-A960-C342BC9915E5Q24292132-07252889-A565-4427-AFC3-068CEA607F79Q24301382-2BBE9E88-7E0A-44CB-A702-9CBD4F29DDA6Q24316407-5A1110D9-1290-4595-AD8E-7CFF1715CC6BQ24324060-C3E38200-75AB-494F-A59D-50494DAAF0C9Q24324150-1DCAFEBA-11FF-4E2F-A092-512120FAF464Q24336199-44EB125F-3EAE-45B1-8699-E3CF9DCED7DBQ24337840-10B19389-B6BA-446D-A630-E13F572D7220Q24337932-2B427926-97B5-49C0-9B17-7FE98B390B26Q24681396-0E0D41DE-A1CD-4520-A5CB-868F15C42873Q24801269-412BA4D9-7D4B-406E-99F6-5A830F91812CQ27701731-84D6D5B3-44D2-45CD-A9A7-49B12E711B06Q28114920-29D207E7-3029-49A7-9A3D-4481ECF9C6F4Q28259513-CF79D146-4828-4A2C-AC89-7B9570B215F3Q28292198-69D054D9-2748-4FE1-B32D-6C608A6A16E1Q28363133-E686AF17-29CB-4F04-A6EA-4D7AC064B099Q28504459-0A59134D-714E-47F6-A6D8-8EA79C9F17E1Q28505751-5F090002-0776-4734-8320-937EA7CC821FQ28506157-B2875190-1C69-499E-BE64-657FA22C5D03Q28508093-0917D190-43D6-4157-ACFE-54F43524B1A7Q28508120-0A78F29F-B409-416E-B644-7203B961E037Q28509277-0AE980AA-E83F-4517-B9B5-E95127C172FDQ28509499-B89069FE-8F66-40A2-A7F1-619EC18FDA9FQ28510984-FBE7894D-EAAA-449C-8E09-263839442BE9Q28511332-E6983F21-1181-4ABF-913D-4DA607A363EDQ28512300-DE8D1892-F0C7-4332-8F31-DE6DB257C62EQ28512311-A91BBBA3-ACF6-4723-BB92-1606944F28C5Q28584732-5857EA3C-36CC-46B2-A5CC-673A57483F1BQ28584939-707779AB-770C-41B6-AE09-DC08A38E0D3FQ28585802-D0D41E5F-F53D-4D4E-87DD-1A56A6C886F7Q28585983-54C3D215-1BAF-484B-A996-FBDB57A08E08Q28586044-1D1F6641-D946-4517-884F-20C510D37333Q28586445-5486CA19-5AF8-4D05-B460-457A24AF2769Q28586744-611C2AF6-96F5-4DA3-BC60-39E75CE62C71Q28586949-D5B76165-6C84-472F-8054-9015DDF9F03EQ28588731-215CF0DA-70D5-42CB-943A-62EC5595E9C6Q28588778-5FCA3980-5F8D-478A-82BE-5C1DB1400635Q28589578-023B6FA0-682B-49D6-9A6C-1B2B67381426Q28590528-EF0ACFB8-59ED-4DBA-9C84-E40E135A8A56Q28590693-23A9520C-1C64-4446-A5D3-578DE0A2C15E
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in Hypoxia inducible factor 1, alpha subunit
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
Hypoxia inducible factor 1, alpha subunit
@en
Hypoxia inducible factor 1, alpha subunit
@nl
type
label
Hypoxia inducible factor 1, alpha subunit
@en
Hypoxia inducible factor 1, alpha subunit
@nl
altLabel
ARNT-interacting protein
@en
Hif1a
@en
hypoxia-inducible factor 1-alpha
@en
prefLabel
Hypoxia inducible factor 1, alpha subunit
@en
Hypoxia inducible factor 1, alpha subunit
@nl
P361
P527
P637
P680
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P705
P352
P638
P279
P31
P352
P361
P527
P637
NP_001300848
NP_001300849
XP_006515541
XP_017170450
P680
P681
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P702
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P705
ENSMUSP00000021530
ENSMUSP00000106088
ENSMUSP00000106091