about
P688
Proapoptotic BAX and BAK control multiple initiator caspasesEndoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian developmentApaf1 is required for mitochondrial pathways of apoptosis and brain developmentApoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.Apaf-1 deficiency and neural tube closure defects are found in fog miceCytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosisNucling recruits Apaf-1/pro-caspase-9 complex for the induction of stress-induced apoptosisSpecific ablation of the apoptotic functions of cytochrome C reveals a differential requirement for cytochrome C and Apaf-1 in apoptosisForebrain overgrowth (fog): a new mutation in the mouse affecting neural tube developmentApoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms
P921
Q24298402-F1B51209-D276-4D7E-A701-02EF925F08E6Q24300781-4AED210D-0FF6-4776-BF16-D62186685816Q24317252-AE959135-6F7B-41D6-B34C-6281893DADA5Q28505574-023D2DA5-3EAD-4FF2-A523-9098AC78979DQ28507273-4BC4A952-5716-492C-BF1D-0B4FF9C767F2Q28512476-3C8DCF28-0595-4A3C-B910-FD7F12F7A5E2Q28512752-DBF41DD1-87D1-485A-8358-7D9B6EFFDE8EQ28513434-9D7C7BAB-D077-4A23-AF50-E7B967D9BC7AQ28589907-D741AA84-8A25-4DE7-9996-6294DC9AB82AQ28590089-4155881E-7165-4D1D-93AE-3C5965856BFDQ28595038-FB0A7545-DEA4-445B-9910-B53EAF481D81
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in Apoptotic peptidase activating factor 1
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
Apoptotic peptidase activating factor 1
@en
type
label
Apoptotic peptidase activating factor 1
@en
altLabel
Apaf1
@en
apoptotic protease-activating factor 1
@en
forebrain overgrowth
@en
prefLabel
Apoptotic peptidase activating factor 1
@en
P361
P527
P637
P680
P681
P682
P705
P352
P279
P31
P352
P361
P527
P637
NP_001036023
NP_001269876
P680
P682
P702
P703
P705
ENSMUSP00000020157
ENSMUSP00000124134
ENSMUSP00000124422
ENSMUSP00000124968
ENSMUSP00000125291