about
P688
JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathwayThe MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokinesJNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BADTRAF7 potentiates MEKK3-induced AP1 and CHOP activation and induces apoptosisA beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aidaMarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survivalIdentification of two essential phosphorylated threonine residues in the catalytic domain of Mekk1. Indirect activation by Pak3 and protein kinase CPICK1, an anchoring protein that specifically targets protein kinase Calpha to mitochondria selectively upon serum stimulation in NIH 3T3 cellsRegulation of the activity of MEK kinase 1 (MEKK1) by autophosphorylation within the kinase activation domainEpithelial sheet movement requires the cooperation of c-Jun and MAP3K1Subdomain VIII is a specificity-determining region in MEKK1MEKK1-induced apoptosis is mediated by Smac/Diablo release from the mitochondriaA role for MEK kinase 1 in TGF-beta/activin-induced epithelium movement and embryonic eyelid closureDeciphering gene expression program of MAP3K1 in mouse eyelid morphogenesis
P921
Q22010669-2D090A9A-D926-4A7A-B436-1A6402D6B39FQ24304462-CA1221F4-8CAF-401E-9E57-D8D4D44A76DBQ24309017-A05AFED9-1649-41E7-B2E2-9BBAB94964C4Q24314392-489D249E-674E-4EEE-9D11-6554D24F1394Q24336491-E64BFFA7-93E8-4C0C-AA60-8C43F82B83F2Q24338226-65E2D5AC-4983-4531-9D3A-479EB67077F5Q28305571-E0E7F298-EB3F-4B35-B03A-13E2FA2AA15CQ28506600-F71AF456-5AA1-4907-9703-2DA4465202F7Q28506778-A6E611EC-3202-44C1-8482-0A3E75CA2D27Q28507451-337646E1-92B6-4CD4-8297-07DCF9FA643DQ28507577-85762C58-9936-4076-9C1F-D3A626B7A873Q28585406-EC767DD2-3339-45C1-8BF3-CFD5DF93D242Q28588921-842A00F3-D13E-4184-B488-5AD430CEACD0Q28590184-E0635485-AD0F-4BE7-BB46-C4A08F784DD3
P921
description
mouse protein (annotated by UniProtKB/Swiss-Prot P53349)
@en
proteinë
@sq
proteïne
@nl
بروتين في فأر المنازل
@ar
name
Mitogen-activated protein kinase kinase kinase 1
@en
type
label
Mitogen-activated protein kinase kinase kinase 1
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altLabel
MAPK/ERK kinase kinase 1
@en
MEK kinase 1
@en
MEKK 1
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prefLabel
Mitogen-activated protein kinase kinase kinase 1
@en