about
P688
Crystal structure of NLRC4 reveals its autoinhibition mechanismCryoelectron Tomography of the NAIP5/NLRC4 Inflammasome: Implications for NLR ActivationDifferential activation of the inflammasome by caspase-1 adaptors ASC and IpafCytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via IpafNLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defenseInnate immune recognition of bacterial ligands by NAIPs determines inflammasome specificityPhosphorylation of NLRC4 is critical for inflammasome activationCytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophagesCryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.Structural and biochemical basis for induced self-propagation of NLRC4.The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion.
P921
Q27684807-F4CF080F-FD34-4152-B17D-3F341AD4462CQ27702694-34ABD52B-2611-4EB8-8F9F-C9CB0F4E19F7Q28266417-8BDD7DE7-DA2D-4B67-9772-4D46AA58328AQ28506503-1FF17C76-9329-4210-B0B4-68F8F5EB997AQ28507530-4B169A53-D6B4-42B6-8223-518FE96460FFQ28508255-3AC0479F-0ED9-4674-AB21-EE934AE1E80DQ28586109-54ECEB83-202F-43DF-A649-C628E4746F80Q28594887-A48EA79F-3607-43DE-B352-CE8F51F11A7CQ36267045-3949A112-39AF-4662-918C-98B250151224Q40451900-04929776-8AB8-4F55-81D9-E648ACEBA32AQ45935076-7C6C27B2-55B8-4CAE-AEC5-101E0B806252
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in NLR family, CARD domain containing 4
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
NLR family, CARD domain containing 4
@en
NLR family, CARD domain containing 4
@nl
type
label
NLR family, CARD domain containing 4
@en
NLR family, CARD domain containing 4
@nl
altLabel
Ipaf
@en
NLR family CARD domain-containing protein 4
@en
Nlrc4
@en
caspase recruitment domain family, member 12
@en
caspase recruitment domain-containing protein 12
@en
ice protease-activating factor
@en
prefLabel
NLR family, CARD domain containing 4
@en
NLR family, CARD domain containing 4
@nl
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ENSMUSP00000059637
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