about
P688
NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinaseActivation of STAT6 by STING is critical for antiviral innate immunityThe ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNAHomeostatic maintenance of pathogen-containing vacuoles requires TBK1-dependent regulation of aquaporin-1The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune responseStructural Insights into the Functions of TBK1 in Innate Antimicrobial ImmunityMurine gammaherpesvirus 68 encoding open reading frame 11 targets TANK binding kinase 1 to negatively regulate the host type I interferon responseThe helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune responseImmune activation of type I IFNs by Listeria monocytogenes occurs independently of TLR4, TLR2, and receptor interacting protein 2 but involves TNFR-associated NF kappa B kinase-binding kinase 1Critical role of AZI2 in GM-CSF-induced dendritic cell differentiationIntracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase BtkNLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STINGTrex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genesBruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral responseLPS-induced down-regulation of signal regulatory protein {alpha} contributes to innate immune activation in macrophages.The Type I Interferon-IRF7 Axis Mediates Transcriptional Expression of Usp25 Gene.Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism.
P921
Q22010870-B8B41B0D-3865-4E17-81F0-BBEEAD17AC96Q24293312-EDA731D0-599B-4939-B284-FF5741854E4CQ24306840-9716CB33-7152-44A8-979A-B19E8FD340DDQ24318634-3C6484DC-4DBF-4DDB-949F-5FF18BECCABDQ24336273-EA24F6B4-D380-46AD-BA84-C9BE7AA7AFCFQ27678533-E0D465A2-1415-42D8-A256-A04AE74F02F9Q28115030-B9CCFAD8-DA5B-4846-A96A-E6FB94CA5D49Q28510485-709B2B64-6CD0-417D-A8E8-8D82ED8D3BBFQ28511836-BBFF5F9C-2DFD-4C3E-9DDC-61C3DCDEB16BQ28513863-3C96AD08-FE72-4D51-ACAC-A6AED180E290Q28587736-40AAC722-E334-4ABF-9484-0670DA4AEBB1Q28975619-ED9F0C96-E1AF-4094-ADB7-FC223594FA2FQ34312364-E120B921-DEB9-4C3D-B926-ED362304BBAAQ35889249-1C9C5C4B-495C-4DBA-9D92-D6304E637855Q36229103-B5216D11-C8D6-46E7-85C2-E36F6BA67244Q37065903-98D22432-395E-4E3D-AC32-78BB5C0AC7D8Q37612521-63EB90D1-1579-41BB-92BA-992776879A18
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in TANK-binding kinase 1
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
TANK-binding kinase 1
@en
TANK-binding kinase 1
@nl
type
label
TANK-binding kinase 1
@en
TANK-binding kinase 1
@nl
altLabel
T2K
@en
Tbk1
@en
serine/threonine-protein kinase TBK1
@en
prefLabel
TANK-binding kinase 1
@en
TANK-binding kinase 1
@nl
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ENSMUSP00000020316
ENSMUSP00000151440
ENSMUSP00000151935