Identification of an important cysteine residue in human glutamate-cysteine ligase catalytic subunit by site-directed mutagenesis
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Thiol-based regulation of redox-active glutamate-cysteine ligase from Arabidopsis thalianaPosttranslational modification and regulation of glutamate-cysteine ligase by the α,β-unsaturated aldehyde 4-hydroxy-2-nonenalStructure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligaseManipulation of cellular GSH biosynthetic capacity via TAT-mediated protein transduction of wild-type or a dominant-negative mutant of glutamate cysteine ligase alters cell sensitivity to oxidant-induced cytotoxicityMechanistic Details of Glutathione Biosynthesis Revealed by Crystal Structures of Saccharomyces cerevisiae Glutamate Cysteine LigaseAdaptive Posttranslational Control in Cellular Stress Response Pathways and Its Relationship to Toxicity Testing and Safety AssessmentDifferential regulation of glutamate-cysteine ligase subunit expression and increased holoenzyme formation in response to cysteine deprivationRapid activation of glutamate cysteine ligase following oxidative stress.The modifier subunit of Drosophila glutamate-cysteine ligase regulates catalytic activity by covalent and noncovalent interactions and influences glutathione homeostasis in vivo.A systems biology perspective on Nrf2-mediated antioxidant responseMulti-faceted regulation of gamma-glutamylcysteine synthetase.Structural basis for the redox control of plant glutamate cysteine ligase.Enzymatic defects underlying hereditary glutamate cysteine ligase deficiency are mitigated by association of the catalytic and regulatory subunitsCaspase-3-Dependent Cleavage of the Glutamate-L-Cysteine Ligase Catalytic Subunit during Apoptotic Cell DeathEmerging regulatory paradigms in glutathione metabolism.Glutathione homeostasis and redox-regulation by sulfhydryl groups.Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells.Genomic analyses reveal a conserved glutathione homeostasis pathway in the invertebrate chordate Ciona intestinalis.Age-associated perturbations in glutathione synthesis in mouse liver.Toxicity of Glutathione-Binding Metals: A Review of Targets and Mechanisms.The Central Role of Amino Acids in Cancer Redox Homeostasis: Vulnerability Points of the Cancer Redox Code.Redox-dependent stability of the γ-glutamylcysteine synthetase enzyme of Escherichia coli: a novel means of redox regulation.
P2860
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P2860
Identification of an important cysteine residue in human glutamate-cysteine ligase catalytic subunit by site-directed mutagenesis
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Identification of an important ...... t by site-directed mutagenesis
@ast
Identification of an important ...... t by site-directed mutagenesis
@en
Identification of an important ...... t by site-directed mutagenesis
@en-gb
Identification of an important ...... t by site-directed mutagenesis
@nl
type
label
Identification of an important ...... t by site-directed mutagenesis
@ast
Identification of an important ...... t by site-directed mutagenesis
@en
Identification of an important ...... t by site-directed mutagenesis
@en-gb
Identification of an important ...... t by site-directed mutagenesis
@nl
prefLabel
Identification of an important ...... t by site-directed mutagenesis
@ast
Identification of an important ...... t by site-directed mutagenesis
@en
Identification of an important ...... t by site-directed mutagenesis
@en-gb
Identification of an important ...... t by site-directed mutagenesis
@nl
P2860
P921
P356
P1433
P1476
Identification of an important ...... t by site-directed mutagenesis
@en
P2860
P304
P356
10.1042/BJ3360675
P407
P478
336 ( Pt 3)
P577
1998-12-15T00:00:00Z