EYA4, a novel vertebrate gene related to Drosophila eyes absent
about
Cooperation of six and eya in activation of their target genes through nuclear translocation of EyaSix1 and Eya1 expression can reprogram adult muscle from the slow-twitch phenotype into the fast-twitch phenotypeMultiple Functions of the Eya Phosphotyrosine PhosphataseThe alpha subunits of Gz and Gi interact with the eyes absent transcription cofactor Eya2, preventing its interaction with the six class of homeodomain-containing proteinsEya1 is required for the morphogenesis of mammalian thymus, parathyroid and thyroidEYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner earEya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodesEya1 regulates the growth of otic epithelium and interacts with Pax2 during the development of all sensory areas in the inner earMisexpression of the eyes absent family triggers the apoptotic programEya4-deficient mice are a model for heritable otitis media.Determination of the embryonic inner ear.Exome Sequencing Identifies a Mutation in EYA4 as a Novel Cause of Autosomal Dominant Non-Syndromic Hearing Loss.Novel method for high throughput DNA methylation marker evaluation using PNA-probe library hybridization and MALDI-TOF detection.Genome-wide discovery of Pax7 target genes during development.Pleiotropic effects in Eya3 knockout mice.Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis.Synergistic regulation of vertebrate muscle development by Dach2, Eya2, and Six1, homologs of genes required for Drosophila eye formation.EWS/FLI1 regulates EYA3 in Ewing sarcoma via modulation of miRNA-708, resulting in increased cell survival and chemoresistance.Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss.Identification of I411K, a novel missense EYA4 mutation causing autosomal dominant non‑syndromic hearing lossUsing Drosophila to decipher how mutations associated with human branchio-oto-renal syndrome and optical defects compromise the protein tyrosine phosphatase and transcriptional functions of eyes absentMolecular analysis of Drosophila eyes absent mutants reveals features of the conserved Eya domainNon-syndromic autosomal-dominant deafness.The MET gene is a common integration target in avian leukosis virus subgroup J-induced chicken hemangiomas.Molecular conservation and novelties in vertebrate ear development.Supratentorial and spinal pediatric ependymomas display a hypermethylated phenotype which includes the loss of tumor suppressor genes involved in the control of cell growth and death.The Eyes Absent proteins in development and disease.A molecular analysis of neurogenic placode and cranial sensory ganglion development in the shark, Scyliorhinus canicula.Relationship between the expression of hTERT and EYA4 mRNA in peripheral blood mononuclear cells with the progressive stages of carcinogenesis of the esophagus.Unraveling the genetics of otitis media: from mouse to human and back again.The EYA-SO/SIX complex in development and disease.Time course and side-by-side analysis of mesodermal, pre-myogenic, myogenic and differentiated cell markers in the chicken model for skeletal muscle formation.A novel mutation of EYA4 in a large Chinese family with autosomal dominant middle-frequency sensorineural hearing loss by targeted exome sequencing.Eya1-Six1 interaction is sufficient to induce hair cell fate in the cochlea by activating Atoh1 expression in cooperation with Sox2.A comparative study of Eya1 and Eya4 protein function and its implication in branchio-oto-renal syndrome and DFNA10Pax3 is essential for skeletal myogenesis and the expression of Six1 and Eya2.DNA methylation profiling identifies EYA4 gene as a prognostic molecular marker in hepatocellular carcinoma.Mutations that impair Eyes absent tyrosine phosphatase activity in vitro reduce robustness of retinal determination gene network output in Drosophila.Pax3 and Dach2 positive regulation in the developing somite.EYA4 Acts as a New Tumor Suppressor Gene in Colorectal Cancer.
P2860
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P2860
EYA4, a novel vertebrate gene related to Drosophila eyes absent
description
1999 nî lūn-bûn
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1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
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1999年の論文
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1999年学术文章
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1999年学术文章
@zh-cn
1999年学术文章
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1999年学术文章
@zh-my
1999年学术文章
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1999年學術文章
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name
EYA4, a novel vertebrate gene related to Drosophila eyes absent
@ast
EYA4, a novel vertebrate gene related to Drosophila eyes absent
@en
EYA4, a novel vertebrate gene related to Drosophila eyes absent
@en-gb
EYA4, a novel vertebrate gene related to Drosophila eyes absent
@nl
type
label
EYA4, a novel vertebrate gene related to Drosophila eyes absent
@ast
EYA4, a novel vertebrate gene related to Drosophila eyes absent
@en
EYA4, a novel vertebrate gene related to Drosophila eyes absent
@en-gb
EYA4, a novel vertebrate gene related to Drosophila eyes absent
@nl
prefLabel
EYA4, a novel vertebrate gene related to Drosophila eyes absent
@ast
EYA4, a novel vertebrate gene related to Drosophila eyes absent
@en
EYA4, a novel vertebrate gene related to Drosophila eyes absent
@en-gb
EYA4, a novel vertebrate gene related to Drosophila eyes absent
@nl
P2093
P50
P921
P356
P1476
EYA4, a novel vertebrate gene related to Drosophila eyes absent
@en
P2093
A DeGrandi
K Metcalfe
M Robertson
P356
10.1093/HMG/8.1.11
P407
P577
1999-01-01T00:00:00Z