Cloning, expression, and characterization of a novel UDP-galactose:beta-N-acetylglucosamine beta1,3-galactosyltransferase (beta3Gal-T5) responsible for synthesis of type 1 chain in colorectal and pancreatic epithelia and tumor cells derived therefrom
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Identification and characterization of three novel beta 1,3-N-acetylglucosaminyltransferases structurally related to the beta 1,3-galactosyltransferase familyMolecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycansSynthesis of disialyl Lewis a (Le(a)) structure in colon cancer cell lines by a sialyltransferase, ST6GalNAc VI, responsible for the synthesis of alpha-series gangliosidesAn endogenous retroviral long terminal repeat is the dominant promoter for human beta1,3-galactosyltransferase 5 in the colonMolecular cloning of a human UDP-galactose:GlcNAcbeta1,3GalNAc beta1, 3 galactosyltransferase gene encoding an O-linked core3-elongation enzymeKnockout of mouse beta 1,4-galactosyltransferase-1 gene results in a dramatic shift of outer chain moieties of N-glycans from type 2 to type 1 chains in hepatic membrane and plasma glycoproteinsRegulation of differentiation- and proliferation-inducers on Lewis antigens, alpha-fucosyltransferase and metastatic potential in hepatocarcinoma cellsA novel human beta1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAcbeta1-3GlcNAcMolecular cloning and characterization of UDP-GlcNAc:lactosylceramide beta 1,3-N-acetylglucosaminyltransferase (beta 3Gn-T5), an essential enzyme for the expression of HNK-1 and Lewis X epitopes on glycolipidsFunctional assignment of motifs conserved in beta 1,3-glycosyltransferasesExpression cloning of human globoside synthase cDNAs. Identification of beta 3Gal-T3 as UDP-N-acetylgalactosamine:globotriaosylceramide beta 1,3-N-acetylgalactosaminyltransferase.Chemoenzymatic synthesis of biotinylated nucleotide sugars as substrates for glycosyltransferases.Molecular cloning and characterization of a novel UDP-Gal:GalNAc(alpha) peptide beta 1,3-galactosyltransferase (C1Gal-T2), an enzyme synthesizing a core 1 structure of O-glycan.Identification of further elongation and branching of dimeric type 1 chain on lactosylceramides from colonic adenocarcinoma by tandem mass spectrometry sequencing analyses.O-glycan inhibitors generate aryl-glycans, induce apoptosis and lead to growth inhibition in colorectal cancer cell lines.Characterization of H type 1 and type 1 N-acetyllactosamine glycan epitopes on ovarian cancer specifically recognized by the anti-glycan monoclonal antibody mAb-A4.High-throughput mass finger printing and Lewis blood group assignment of human milk oligosaccharides.Molecular basis of the globoside-deficient P(k) blood group phenotype. Identification of four inactivating mutations in the UDP-N-acetylgalactosamine: globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase gene.Molecular cloning and characterization of a novel chondroitin sulfate glucuronyltransferase that transfers glucuronic acid to N-acetylgalactosamine.Suppression of beta 1,3galactosyltransferase beta 3Gal-T5 in cancer cells reduces sialyl-Lewis a and enhances poly N-acetyllactosamines and sialyl-Lewis x on O-glycans.Control of Glycosylation-Related Genes by DNA Methylation: the Intriguing Case of the B3GALT5 Gene and Its Distinct PromotersStructures and application of oligosaccharides in human milk.Molecular genetic analysis of the glycosyltransferase Fringe in Drosophila.Blood Groups in Infection and Host Susceptibility.Identification of mono- and disulfated N-acetyl-lactosaminyl Oligosaccharide structures as epitopes specifically recognized by humanized monoclonal antibody HMOCC-1 raised against ovarian cancer.Glycosyltransferases involved in the synthesis of MUC-associated metastasis-promoting selectin ligands.Glycosphingolipid dynamics in human embryonic stem cell and cancer: their characterization and biomedical implications.Altered glycosylation of proteins produced by malignant cells, and application for the diagnosis and immunotherapy of tumours.Regulation of glycan structures in animal tissues: transcript profiling of glycan-related genes.Noroviruses distinguish between type 1 and type 2 histo-blood group antigens for binding.Selectin Ligands Sialyl-Lewis a and Sialyl-Lewis x in Gastrointestinal Cancers.The role of molecular mimicry and other factors in the association of Human Endogenous Retroviruses and autoimmunity.Expression of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-12 in gastric and colonic cancer cell lines and in human colorectal cancer.A high proportion of chromosome 21 promoter polymorphisms influence transcriptional activity.Transfection of the c-erbB2/neu gene upregulates the expression of sialyl Lewis X, alpha1,3-fucosyltransferase VII, and metastatic potential in a human hepatocarcinoma cell line.Genomic DNA insertions and deletions occur frequently between humans and nonhuman primates.High expression FUT1 and B3GALT5 is an independent predictor of postoperative recurrence and survival in hepatocellular carcinoma.A novel member of the glycosyltransferase family, beta 3 Gn-T2, highly downregulated in invasive human bladder transitional cell carcinomas.Shotgun Glycomics Identifies Tumor-Associated Glycan Ligands Bound by an Ovarian Carcinoma-Specific Monoclonal Antibody.The beta 1,3-galactosyltransferase beta 3GalT-V is a stage-specific embryonic antigen-3 (SSEA-3) synthase.
P2860
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P2860
Cloning, expression, and characterization of a novel UDP-galactose:beta-N-acetylglucosamine beta1,3-galactosyltransferase (beta3Gal-T5) responsible for synthesis of type 1 chain in colorectal and pancreatic epithelia and tumor cells derived therefrom
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Cloning, expression, and chara ...... tumor cells derived therefrom
@ast
Cloning, expression, and chara ...... tumor cells derived therefrom
@en
Cloning, expression, and chara ...... tumor cells derived therefrom
@en-gb
Cloning, expression, and chara ...... tumor cells derived therefrom
@nl
type
label
Cloning, expression, and chara ...... tumor cells derived therefrom
@ast
Cloning, expression, and chara ...... tumor cells derived therefrom
@en
Cloning, expression, and chara ...... tumor cells derived therefrom
@en-gb
Cloning, expression, and chara ...... tumor cells derived therefrom
@nl
prefLabel
Cloning, expression, and chara ...... tumor cells derived therefrom
@ast
Cloning, expression, and chara ...... tumor cells derived therefrom
@en
Cloning, expression, and chara ...... tumor cells derived therefrom
@en-gb
Cloning, expression, and chara ...... tumor cells derived therefrom
@nl
P2093
P356
P1476
Cloning, expression, and chara ...... tumor cells derived therefrom
@en
P2093
A Togayachi
H Narimatsu
M Kitajima
M Watanabe
N Shiraishi
S Nishihara
P304
P356
10.1074/JBC.274.18.12499
P407
P577
1999-04-30T00:00:00Z