UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation
about
The collapsin response mediator protein 1 (CRMP-1) and the promyelocytic leukemia zinc finger protein (PLZF) bind to UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE), the key enzyme of sialic acid biosynthesisMetabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N-glycolylneuraminic acidA structural basis for the allosteric regulation of non-hydrolysing UDP-GlcNAc 2-epimerasesPodocyte pathology and nephropathy - sphingolipids in glomerular diseasesCrystal Structure of the N-Acetylmannosamine Kinase Domain of GNECrystal Structures of N -Acetylmannosamine Kinase Provide Insights into Enzyme Activity and InhibitionPrimary structure and expression analysis of human UDP-N-acetyl-glucosamine-2-epimerase/N-acetylmannosamine kinase, the bifunctional enzyme in neuraminic acid biosynthesisGlcNAc 2-epimerase can serve a catabolic role in sialic acid metabolismHereditary inclusion body myopathy: a decade of progressNon-specific accumulation of glycosphingolipids in GNE myopathyMutation in the key enzyme of sialic acid biosynthesis causes severe glomerular proteinuria and is rescued by N-acetylmannosamineThe proteomic profile of hereditary inclusion body myopathyDomain-specific characteristics of the bifunctional key enzyme of sialic acid biosynthesis, UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinaseIntravenous immune globulin in hereditary inclusion body myopathy: a pilot studyHereditary inclusion-body myopathy with sparing of the quadriceps: the many tiles of an incomplete puzzleNationwide patient registry for GNE myopathy in JapanEffects of altered sialic acid biosynthesis on N-linked glycan branching and cell surface interactionsIdentification of an Alu element-mediated deletion in the promoter region of GNE in siblings with GNE myopathy.Molecular characterization of a first human 3(alpha-->beta)-hydroxysteroid epimerase.Metabolism of diazirine-modified N-acetylmannosamine analogues to photo-cross-linking sialosides.Sialylation is essential for early development in mice.Glycoprotein hyposialylation gives rise to a nephrotic-like syndrome that is prevented by sialic acid administration in GNE V572L point-mutant mice.Sialylation of Thomsen-Friedenreich antigen is a noninvasive blood-based biomarker for GNE myopathy.UDP-GlcNAc 2-Epimerase/ManNAc Kinase (GNE): A Master Regulator of Sialic Acid Synthesis.A preclinical trial of sialic acid metabolites on distal myopathy with rimmed vacuoles/hereditary inclusion body myopathy, a sugar-deficient myopathy: a review.Distal myopathy with rimmed vacuoles: impaired O-glycan formation in muscular glycoproteinsWhole genome analyses of a well-differentiated liposarcoma reveals novel SYT1 and DDR2 rearrangements.Modified GM3 gangliosides produced by metabolic oligosaccharide engineeringGlycosylation of immunoglobulin G determines osteoclast differentiation and bone lossHereditary inclusion body myopathy: single patient response to intravenous dosing of GNE gene lipoplex.Identification of sialylated glycoproteins from metabolically oligosaccharide engineered pancreatic cells.Sialidases as regulators of bioengineered cellular surfaces.Peracetylated N-acetylmannosamine, a synthetic sugar molecule, efficiently rescues muscle phenotype and biochemical defects in mouse model of sialic acid-deficient myopathySizing up sialic acid in glomerular diseaseThe systems biology of glycosylation.The Gne M712T mouse as a model for human glomerulopathy.Metabolic flux increases glycoprotein sialylation: implications for cell adhesion and cancer metastasis.Metabolism of vertebrate amino sugars with N-glycolyl groups: incorporation of N-glycolylhexosamines into mammalian glycans by feeding N-glycolylgalactosamineCellular metabolism of unnatural sialic acid precursors.Conditional control of selectin ligand expression and global fucosylation events in mice with a targeted mutation at the FX locus.
P2860
Q24318382-49791197-F643-461A-BF1C-81AAB0538052Q24338142-67EA037B-E5B4-4FB3-AA88-18E338B88327Q24646011-87DD7C93-1F69-40FB-8B76-E391D02456B0Q26852463-F65855C9-8C53-4BC5-82ED-92E91FE3F227Q27657853-B292440D-1420-4099-9342-EBFDD2BE1008Q27677332-C426D00C-C169-4663-9EDB-8F5FF3669DA2Q28141095-28266546-83E0-4FE7-8181-9E95FFBD1577Q28218950-F3E1A1DB-9020-473A-96F7-788D0237FF55Q28251720-9BDB9372-AF6E-49AF-872C-19809A36E2D8Q28300410-0CF94639-3244-4032-98DD-DF00B5711654Q28305085-905C6F91-BC05-4A90-B44D-2001B94FB34BQ28477028-CFD14FD5-006F-4D86-B5CE-FB8F2713861EQ28569398-6DDE4CFF-E9A1-4139-B773-C4F669821692Q33270749-B870A9C5-532B-4D00-9C3D-D1D5FD25F347Q33352578-08D2845D-03D6-49D8-A304-7F9E604FF771Q33418112-830415BD-D3F9-46DB-B78B-FA6B6AD9FE0AQ33781368-2F6133A8-BA57-4E62-A58B-B0CBD35A3A0EQ33907000-0BB8D148-4CA9-4F13-97E4-B020C9DB4649Q33909706-C3169835-D2D3-4C01-8A43-F08B2ACD4B9BQ33991792-A7AD2923-46B8-4A3C-A63D-12A8A80643B8Q34024283-F5948EC4-366B-4486-8543-F647B2A251F2Q34130746-7BF79D35-37E5-43D0-B592-D82DB4A92E2AQ34160071-4C7FD7A0-E417-46E6-8571-6B61ACC6D9E0Q34167791-BD6F8EE4-6F76-4590-98B3-F66D3C9094D0Q34409454-606D14D1-EC9D-47B4-ABC4-6CF76E2F3EBAQ35083807-5FDB4E23-CC30-40BD-847F-DC4C62971757Q35088118-2BAF38DA-D3D7-483A-9BAA-FC121EBC0C6BQ35165149-37F5F7D7-2A28-4A5E-811F-C898BE8881D9Q35311994-971B8DE7-C8E6-4CF9-ADAE-836683795CFEQ35575697-54516D6E-2592-4942-8455-81FD71C524A5Q35615401-DC86957B-96FC-4F31-B87C-235100C68960Q35678457-78D76038-9A33-402E-A46A-DA809F525D8FQ35710052-C5C29B06-E02D-41D7-A61D-B4625A788FE1Q35813769-AC35D44F-0F6C-49D2-9CDC-8DF9D232151DQ35905293-B5F233DD-E700-4010-A9CA-1FC3099C580AQ35952076-860DB699-EAA1-4C9F-813D-A3E9E695E9CAQ36089893-7E1F65CA-EFA4-450F-8221-6C438569561FQ36217214-5862BA70-D7D8-4184-82F9-F2A2348433B9Q36270708-EA1E3D30-87DB-4833-8FE9-E4E98CC4F523Q36325665-7E69A0A3-5171-43EA-8190-03F6986A1182
P2860
UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation
@ast
UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation
@en
UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation
@en-gb
UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation
@nl
type
label
UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation
@ast
UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation
@en
UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation
@en-gb
UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation
@nl
prefLabel
UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation
@ast
UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation
@en
UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation
@en-gb
UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation
@nl
P2093
P4510
P921
P3181
P1433
P1476
UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation
@en
P2093
O T Keppler
R Schwartz-Albiez
S Hinderlich
P304
P3181
P356
10.1126/SCIENCE.284.5418.1372
P407
P577
1999-05-21T00:00:00Z