cDNA cloning, expression and activity of a second human aflatoxin B1-metabolizing member of the aldo-keto reductase superfamily, AKR7A3
about
Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family membersNovel homodimeric and heterodimeric rat gamma-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct subclass of aldo-keto reductase 7 family proteinsAntioxidative function and substrate specificity of NAD(P)H-dependent alkenal/one oxidoreductase. A new role for leukotriene B4 12-hydroxydehydrogenase/15-oxoprostaglandin 13-reductaseChanges in gene expression induced by tienilic Acid and sulfamethoxazole: testing the danger hypothesisContributions of human enzymes in carcinogen metabolismProteome analysis of rat hepatomas: carcinogen-dependent tumor-associated protein variants.Genetic or pharmacologic activation of Nrf2 signaling fails to protect against aflatoxin genotoxicity in hypersensitive GSTA3 knockout miceHuman aldo-keto reductases: Function, gene regulation, and single nucleotide polymorphisms.Quantitative evaluation of aldo-keto reductase expression in hepatocellular carcinoma (HCC) cell lines.Oxidative and reductive metabolism of lipid-peroxidation derived carbonyls.Aldo-keto reductases and formation of polycyclic aromatic hydrocarbon o-quinones.Testing an aflatoxin B1 gene signature in rat archival tissues.Molecular Changes in the Nasal Cavity after N, N-dimethyl-p-toluidine Exposure.Physiologically based toxicokinetics of serum aflatoxin B1-lysine adduct in F344 rats.Transgenic expression of aflatoxin aldehyde reductase (AKR7A1) modulates aflatoxin B1 metabolism but not hepatic carcinogenesis in the rat.Human aldo-keto reductases: structure, substrate specificity and roles in tumorigenesis.Protection against aflatoxin B1-induced cytotoxicity by expression of the cloned aflatoxin B1-aldehyde reductases rat AKR7A1 and human AKR7A3An aldo-keto reductase is responsible for Fusarium toxin-degrading activity in a soil Sphingomonas strain.Lophirones B and C extenuate AFB1-mediated oxidative onslaught on cellular proteins, lipids, and DNA through Nrf-2 expression.Purification from rat liver of a novel constitutively expressed member of the aldo-keto reductase 7 family that is widely distributed in extrahepatic tissues.Characterisation of a novel mouse liver aldo-keto reductase AKR7A5.Gene expression-based in vivo and in vitro prediction of liver toxicity allows compound selection at an early stage of drug development.The aldo-keto reductase superfamily and its role in drug metabolism and detoxificationMethods for Detection of Aflatoxins in Agricultural Food Crops
P2860
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P2860
cDNA cloning, expression and activity of a second human aflatoxin B1-metabolizing member of the aldo-keto reductase superfamily, AKR7A3
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
cDNA cloning, expression and a ...... reductase superfamily, AKR7A3
@ast
cDNA cloning, expression and a ...... reductase superfamily, AKR7A3
@en
cDNA cloning, expression and a ...... reductase superfamily, AKR7A3
@en-gb
cDNA cloning, expression and a ...... reductase superfamily, AKR7A3
@nl
type
label
cDNA cloning, expression and a ...... reductase superfamily, AKR7A3
@ast
cDNA cloning, expression and a ...... reductase superfamily, AKR7A3
@en
cDNA cloning, expression and a ...... reductase superfamily, AKR7A3
@en-gb
cDNA cloning, expression and a ...... reductase superfamily, AKR7A3
@nl
prefLabel
cDNA cloning, expression and a ...... reductase superfamily, AKR7A3
@ast
cDNA cloning, expression and a ...... reductase superfamily, AKR7A3
@en
cDNA cloning, expression and a ...... reductase superfamily, AKR7A3
@en-gb
cDNA cloning, expression and a ...... reductase superfamily, AKR7A3
@nl
P2093
P921
P356
P1433
P1476
cDNA cloning, expression and a ...... reductase superfamily, AKR7A3
@en
P2093
J D Groopman
L P Knight
T Primiano
T R Sutter
T W Kensler
P304
P356
10.1093/CARCIN/20.7.1215
P407
P577
1999-07-01T00:00:00Z