Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
about
Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressorHuman pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factorsBRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II.Nuclear deadenylation/polyadenylation factors regulate 3' processing in response to DNA damage.Complex protein interactions within the human polyadenylation machinery identify a novel componentCapping, splicing, and 3' processing are independently stimulated by RNA polymerase II: different functions for different segments of the CTDThe ankyrin repeat as molecular architecture for protein recognition3' end mRNA processing: molecular mechanisms and implications for health and diseaseRecognition of GU-rich polyadenylation regulatory elements by human CstF-64 proteinBinding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complexConserved and specific functions of mammalian ssu72Processing and transcriptome expansion at the mRNA 3' end in health and disease: finding the right endHexameric architecture of CstF supported by CstF-50 homodimerization domain structureNuclear-cytoplasmic shuttling of BARD1 contributes to its proapoptotic activity and is regulated by dimerization with BRCA1BRCA1 associates with processive RNA polymerase IIThe RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutationA novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancerIdentification of proteins that interact with BRCA1 by Far-Western library screeningBARD1 induces BRCA1 intranuclear foci formation by increasing RING-dependent BRCA1 nuclear import and inhibiting BRCA1 nuclear exportRedistribution of BRCA1 among four different protein complexes following replication blockageIdentification of residues required for the interaction of BARD1 with BRCA1Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 proteinIs there more to BARD1 than BRCA1?Structural biology of poly(A) site definitionMinding the gap: the underground functions of BRCA1 and BRCA2 at stalled replication forksLoss of Bard1, the heterodimeric partner of the Brca1 tumor suppressor, results in early embryonic lethality and chromosomal instabilityBARD1 participates with BRCA1 in homology-directed repair of chromosome breaksConcerted transcriptional regulation by BRCA1 and COBRA1 in breast cancer cellsDelineating the structural blueprint of the pre-mRNA 3'-end processing machinery.Nucleophosmin is selectively deposited on mRNA during polyadenylation.Structural basis to stabilize the domain motion of BARD1-ARD BRCT by CstF50.Molecular mechanisms of eukaryotic pre-mRNA 3' end processing regulation.Functional communication between endogenous BRCA1 and its partner, BARD1, during Xenopus laevis development.BRCA1 and cell signaling.Lessons learned from BRCA1 and BRCA2.BRCA1 and prostate cancer.Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damageLiterature curation of protein interactions: measuring agreement across major public databasesEssential role for the interaction between hnRNP H/F and a G quadruplex in maintaining p53 pre-mRNA 3'-end processing and function during DNA damage.The Drosophila mus101 gene, which links DNA repair, replication and condensation of heterochromatin in mitosis, encodes a protein with seven BRCA1 C-terminus domains.
P2860
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P2860
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
@ast
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
@en
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
@en-gb
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
@nl
type
label
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
@ast
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
@en
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
@en-gb
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
@nl
prefLabel
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
@ast
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
@en
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
@en-gb
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
@nl
P3181
P1433
P1476
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
@en
P2093
F E Kleiman
J L Manley
P304
P3181
P356
10.1126/SCIENCE.285.5433.1576
P407
P577
1999-09-03T00:00:00Z