Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein
about
Interaction of protein tyrosine phosphatase (PTP) 1B with its substrates is influenced by two distinct binding domainsThe tyrosine phosphatase 1B regulates linker for activation of T-cell phosphorylation and platelet aggregation upon FcgammaRIIa cross-linkingThe role of the C-terminal domain of protein tyrosine phosphatase-1B in phosphatase activity and substrate bindingObesity and insulin resistanceGenes, diet and type 2 diabetes mellitus: a reviewThe mammalian tribbles homolog TRIB3, glucose homeostasis, and cardiovascular diseasesConformation-Sensing Antibodies Stabilize the Oxidized Form of PTP1B and Inhibit Its Phosphatase ActivityProtein-tyrosine Phosphatase and Kinase Specificity in Regulation of SRC and Breast Tumor KinasePTEN is a protein tyrosine phosphatase for IRS1Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistanceCoordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTPNck1 depletion induces activation of the PI3K/Akt pathway by attenuating PTP1B protein expression.Exploring protein structure and dynamics through a project-oriented biochemistry laboratory module.Inhibition of vagally mediated immune-to-brain signaling by vanadyl sulfate speeds recovery from sickness.Analysis of common PTPN1 gene variants in type 2 diabetes, obesity and associated phenotypes in the French populationInsulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation.Quercetin suppresses MIP-1α-induced adipose inflammation by downregulating its receptors CCR1/CCR5 and inhibiting inflammatory signaling.Exercise and Glycemic Control: Focus on Redox Homeostasis and Redox-Sensitive Protein Signaling.Regulation of brown fat adipogenesis by protein tyrosine phosphatase 1BInsulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1b in vivo and enhances the early insulin action cascade.PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice.Curcumin inhibits hepatic protein-tyrosine phosphatase 1B and prevents hypertriglyceridemia and hepatic steatosis in fructose-fed rats.MSI-1436 reduces acute food intake without affecting dopamine transporter activity.Synthesis, biology and clinical significance of pentacyclic triterpenes: a multi-target approach to prevention and treatment of metabolic and vascular diseases.Increased insulin sensitivity and reduced adiposity in phosphatidylinositol 5-phosphate 4-kinase beta-/- miceProtein tyrosine phosphatases as potential therapeutic targets.Coordinated action of protein tyrosine phosphatases in insulin signal transduction.Dephosphorylation by default, a potential mechanism for regulation of insulin receptor substrate-1/2, Akt, and ERK1/2.Redox-based probes as tools to monitor oxidized protein tyrosine phosphatases in living cells.Redox paradox: insulin action is facilitated by insulin-stimulated reactive oxygen species with multiple potential signaling targetsProtein tyrosine phosphatase 1B: a new target for the treatment of obesity and associated co-morbidities.Tea contains potent inhibitors of tyrosine phosphatase PTP1B.The uncovering of a novel regulatory mechanism for PLD2: formation of a ternary complex with protein tyrosine phosphatase PTP1B and growth factor receptor-bound protein GRB2.Metabolic effects of obesity: A reviewModulation of the central melanocortin system by leptin, insulin, and serotonin: co-ordinated actions in a dispersed neuronal network.Protein tyrosine phosphatase 1B deficiency ameliorates murine experimental colitis via the expansion of myeloid-derived suppressor cellsDysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer's disease.Protein-tyrosine phosphatase 1B substrates and metabolic regulationDisrupted anabolic and catabolic processes may contribute to alcohol-accentuated SAIDS-associated wastingThe exquisite regulation of PLD2 by a wealth of interacting proteins: S6K, Grb2, Sos, WASp and Rac2 (and a surprise discovery: PLD2 is a GEF).
P2860
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P2860
Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein
description
2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Tyrosine dephosphorylation and ...... with the Grb2 adaptor protein
@ast
Tyrosine dephosphorylation and ...... with the Grb2 adaptor protein
@en
Tyrosine dephosphorylation and ...... with the Grb2 adaptor protein
@en-gb
Tyrosine dephosphorylation and ...... with the Grb2 adaptor protein
@nl
type
label
Tyrosine dephosphorylation and ...... with the Grb2 adaptor protein
@ast
Tyrosine dephosphorylation and ...... with the Grb2 adaptor protein
@en
Tyrosine dephosphorylation and ...... with the Grb2 adaptor protein
@en-gb
Tyrosine dephosphorylation and ...... with the Grb2 adaptor protein
@nl
prefLabel
Tyrosine dephosphorylation and ...... with the Grb2 adaptor protein
@ast
Tyrosine dephosphorylation and ...... with the Grb2 adaptor protein
@en
Tyrosine dephosphorylation and ...... with the Grb2 adaptor protein
@en-gb
Tyrosine dephosphorylation and ...... with the Grb2 adaptor protein
@nl
P2093
P356
P1476
Tyrosine dephosphorylation and ...... with the Grb2 adaptor protein
@en
P2093
A Bittner-Kowalczyk
B J Goldstein
P304
P356
10.1074/JBC.275.6.4283
P407
P577
2000-02-11T00:00:00Z