Purified E255L Mutant SERCA1a and Purified PfATP6 Are Sensitive to SERCA-type Inhibitors but Insensitive to Artemisinins - Wikidata - awgldk - TriplyDB

Purified E255L Mutant SERCA1a and Purified PfATP6 Are Sensitive to SERCA-type Inhibitors but Insensitive to Artemisinins

Purified E255L Mutant SERCA1a and Purified PfATP6 Are Sensitive to SERCA-type Inhibitors but Insensitive to Artemisinins

http://www.wikidata.org/entity/Q22061846

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Expression in Yeast Links Field Polymorphisms in PfATP6 to in Vitro Artemisinin Resistance and Identifies New Inhibitor Classes Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate Drug resistance genomics of the antimalarial drug artemisinin Active detergent-solubilized H+,K+-ATPase is a monomer In vitro sensitivity of Plasmodium falciparum from China-Myanmar border area to major ACT drugs and polymorphisms in potential target genes Characterization of the differences in the cyclopiazonic acid binding mode to mammalian and P. Falciparum Ca2+ pumps: a computational study A high-yield co-expression system for the purification of an intact Drs2p-Cdc50p lipid flippase complex, critically dependent on and stabilized by phosphatidylinositol-4-phosphate.Antimalarial screening via large-scale purification of Plasmodium falciparum Ca2+-ATPase 6 and in vitro studies.PfCRT-mediated drug transport in malarial parasites.Overexpression of membrane proteins from higher eukaryotes in yeasts.Investigating the antimalarial action of 1,2,4-trioxolanes with fluorescent chemical probes Lack of association of the S769N mutation in Plasmodium falciparum SERCA (PfATP6) with resistance to artemisinins.Examination of the cytotoxic and embryotoxic potential and underlying mechanisms of next-generation synthetic trioxolane and tetraoxane antimalarials Ca(2+) monitoring in Plasmodium falciparum using the yellow cameleon-Nano biosensor.Total and putative surface proteomics of malaria parasite salivary gland sporozoites.1,4-naphthoquinones and other NADPH-dependent glutathione reductase-catalyzed redox cyclers as antimalarial agents The purified mechanosensitive channel TREK-1 is directly sensitive to membrane tension.The molecular and cellular action properties of artemisinins: what has yeast told us?A general approach to the basiliolide/transtaganolide natural products: total syntheses of basiliolide B, epi-8-basiliolide B, transtaganolide C, and transtaganolide D.Drug Interactions With the Ca2+-ATPase From Sarco(Endo)Plasmic Reticulum (SERCA).Targeting Channels and Transporters in Protozoan Parasite Infections.Profiling of the anti-malarial drug candidate SC83288 against artemisinins in Plasmodium falciparum.

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P2860

Purified E255L Mutant SERCA1a and Purified PfATP6 Are Sensitive to SERCA-type Inhibitors but Insensitive to Artemisinins

http://www.wikidata.org/entity/Q22061846

description

2010 nî lūn-bûn

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2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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P2860

Qinghaosu (Artemisinin): The Price of Success

Yeast model uncovers dual roles of mitochondria in action of artemisinin.

Effect of Artemisinins and Amino Alcohol Partner Antimalarials on Mammalian Sarcoendoplasmic Reticulum Calcium Adenosine Triphosphatase Activity

Artemisinin Resistance in Plasmodium falciparum Malaria

A single amino acid residue can determine the sensitivity of SERCAs to artemisinins

Artemisinins target the SERCA of Plasmodium falciparum

Current perspectives on the mechanism of action of artemisinins

The codon Adaptation Index--a measure of directional synonymous codon usage bias, and its potential applications

Measurement of protein using bicinchoninic acid

Artemisinins: their growing importance in medicine

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