Differential biosynthesis of polysialic acid on neural cell adhesion molecule (NCAM) and oligosaccharide acceptors by three distinct alpha 2,8-sialyltransferases, ST8Sia IV (PST), ST8Sia II (STX), and ST8Sia III
about
Enzymatic synthesis in vitro of the disulfated disaccharide unit of corneal keratan sulfateStructure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylationMolecular cloning and expression of a human hST8Sia VI (alpha2,8-sialyltransferase) responsible for the synthesis of the diSia motif on O-glycosylproteinsStructure and Mutagenesis of Neural Cell Adhesion Molecule Domains: EVIDENCE FOR FLEXIBILITY IN THE PLACEMENT OF POLYSIALIC ACID ATTACHMENT SITESPharmacological inhibition of polysialyltransferase ST8SiaII modulates tumour cell migrationThe transcriptional profiling of glycogenes associated with hepatocellular carcinoma metastasisEvolutionary history of the alpha2,8-sialyltransferase (ST8Sia) gene family: tandem duplications in early deuterostomes explain most of the diversity found in the vertebrate ST8Sia genes.X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid.Unique disulfide bond structures found in ST8Sia IV polysialyltransferase are required for its activity.Genome-wide association study of bipolar I disorder in the Han Chinese population.ST8Sia II and ST8Sia IV polysialyltransferases exhibit marked differences in utilizing various acceptors containing oligosialic acid and short polysialic acid. The basis for cooperative polysialylation by two enzymes.Sequences from the first fibronectin type III repeat of the neural cell adhesion molecule allow O-glycan polysialylation of an adhesion molecule chimera.Specific amino acids in the first fibronectin type III repeat of the neural cell adhesion molecule play a role in its recognition and polysialylation by the polysialyltransferase ST8Sia IV/PST.Sequences prior to conserved catalytic motifs of polysialyltransferase ST8Sia IV are required for substrate recognition.Expression and localization of neural cell adhesion molecule and polysialic acid during chick corneal developmentDevelopment of a novel method to evaluate sialylation of glycoproteins and analysis of gp96 sialylation in Hela, SW1990 and A549 cell lines.Regulation of glycan structures in murine embryonic stem cells: combined transcript profiling of glycan-related genes and glycan structural analysis.The polysialyltransferases interact with sequences in two domains of the neural cell adhesion molecule to allow its polysialylationSequence Requirements for Neuropilin-2 Recognition by ST8SiaIV and Polysialylation of Its O-Glycans.Identification of sequences in the polysialyltransferases ST8Sia II and ST8Sia IV that are required for the protein-specific polysialylation of the neural cell adhesion molecule, NCAM.Mucin-type O-glycans in tears of normal subjects and patients with non-Sjögren's dry eyeCMP substitutions preferentially inhibit polysialic acid synthesis.Distinct ontogenic and regional expressions of newly identified Cajal-Retzius cell-specific genes during neocorticogenesis.Polysialic acid: biosynthesis, novel functions and applications.Biosynthesis of HNK-1 glycans on O-linked oligosaccharides attached to the neural cell adhesion molecule (NCAM): the requirement for core 2 beta 1,6-N-acetylglucosaminyltransferase and the muscle-specific domain in NCAM.Sialic acids: biomarkers in endocrinal cancers.Sialic acids in cancer biology and immunity.Sialylation of N-glycans: mechanism, cellular compartmentalization and function.Degree of polymerization (DP) of polysialic acid (polySia) on neural cell adhesion molecules (N-CAMS): development and application of a new strategy to accurately determine the DP of polySia chains on N-CAMS.Occurrence of oligosialic acids on integrin alpha 5 subunit and their involvement in cell adhesion to fibronectin.Polysialic acid on neuropilin-2 is exclusively synthesized by the polysialyltransferase ST8SiaIV and attached to mucin-type o-glycans located between the b2 and c domain.Epitope diversity of N-glycans from bovine peripheral myelin glycoprotein P0 revealed by mass spectrometry and nano probe magic angle spinning 1H NMR spectroscopy.The impact of N-glycosylation on the functions of polysialyltransferases.Dynamic change of neural cell adhesion molecule polysialylation on human neuroblastoma (IMR-32) and rat pheochromocytoma (PC-12) cells during growth and differentiation.Molecular dissection of the ST8Sia IV polysialyltransferase. Distinct domains are required for neural cell adhesion molecule recognition and polysialylation.Enzyme-dependent variations in the polysialylation of the neural cell adhesion molecule (NCAM) in vivo.Autopolysialylation of polysialyltransferases is required for polysialylation and polysialic acid chain elongation on select glycoprotein substrates.The minimal structural domains required for neural cell adhesion molecule polysialylation by PST/ST8Sia IV and STX/ST8Sia II.Polysialic acid profiles of mice expressing variant allelic combinations of the polysialyltransferases ST8SiaII and ST8SiaIV.ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans
P2860
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P248
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P2860
Differential biosynthesis of polysialic acid on neural cell adhesion molecule (NCAM) and oligosaccharide acceptors by three distinct alpha 2,8-sialyltransferases, ST8Sia IV (PST), ST8Sia II (STX), and ST8Sia III
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Differential biosynthesis of p ...... T8Sia II (STX), and ST8Sia III
@ast
Differential biosynthesis of p ...... T8Sia II (STX), and ST8Sia III
@en
Differential biosynthesis of p ...... T8Sia II (STX), and ST8Sia III
@en-gb
Differential biosynthesis of p ...... T8Sia II (STX), and ST8Sia III
@nl
type
label
Differential biosynthesis of p ...... T8Sia II (STX), and ST8Sia III
@ast
Differential biosynthesis of p ...... T8Sia II (STX), and ST8Sia III
@en
Differential biosynthesis of p ...... T8Sia II (STX), and ST8Sia III
@en-gb
Differential biosynthesis of p ...... T8Sia II (STX), and ST8Sia III
@nl
prefLabel
Differential biosynthesis of p ...... T8Sia II (STX), and ST8Sia III
@ast
Differential biosynthesis of p ...... T8Sia II (STX), and ST8Sia III
@en
Differential biosynthesis of p ...... T8Sia II (STX), and ST8Sia III
@en-gb
Differential biosynthesis of p ...... T8Sia II (STX), and ST8Sia III
@nl
P2093
P2860
P921
P356
P1476
Differential biosynthesis of p ...... T8Sia II (STX), and ST8Sia III
@en
P2093
P2860
P304
18594-18601
P356
10.1074/JBC.M910204199
P407
P577
2000-06-01T00:00:00Z