Molecular cloning and characterization of a human mitochondrial ceramidase
about
Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramideAlkaline ceramidase 3 (ACER3) hydrolyzes unsaturated long-chain ceramides, and its down-regulation inhibits both cell proliferation and apoptosisSubstrate specificity, membrane topology, and activity regulation of human alkaline ceramidase 2 (ACER2)Differentiation-associated expression of ceramidase isoforms in cultured keratinocytes and epidermisAlkaline ceramidase 2 regulates beta1 integrin maturation and cell adhesionKilling tumours by ceramide-induced apoptosis: a critique of available drugsThe complex life of simple sphingolipidsIdentification of a novel amidase motif in neutral ceramidaseCeramide channels increase the permeability of the mitochondrial outer membrane to small proteinsCeramide forms channels in mitochondrial outer membranes at physiologically relevant concentrationsCeramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphateA house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell deathA review of ceramide analogs as potential anticancer agentsAlkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the BrainMechanistic Insights into the Hydrolysis and Synthesis of Ceramide by Neutral CeramidaseIsc1 regulates sphingolipid metabolism in yeast mitochondria.The reverse activity of human acid ceramidaseBcR-induced apoptosis involves differential regulation of C16 and C24-ceramide formation and sphingolipid-dependent activation of the proteasomeLactosylceramide contributes to mitochondrial dysfunction in diabetesPurification, characterization, and identification of a sphingomyelin synthase from Pseudomonas aeruginosa. PlcH is a multifunctional enzymeCloning and characterization of a mouse endoplasmic reticulum alkaline ceramidase: an enzyme that preferentially regulates metabolism of very long chain ceramidesRat intestinal ceramidase: purification, properties, and physiological relevance.A novel mitochondrial sphingomyelinase in zebrafish cells.Essential roles of neutral ceramidase and sphingosine in mitochondrial dysfunction due to traumatic brain injury.Cloning and characterization of a wheat neutral ceramidase gene Ta-CDase.Plant sphingolipids: decoding the enigma of the SphinxRole of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes.Phylogenomic evidence for a myxococcal contribution to the mitochondrial fatty acid beta-oxidation.Enlargement and contracture of C2-ceramide channels.Further characterization of mammalian ceramide kinase: substrate delivery and (stereo)specificity, tissue distribution, and subcellular localization studies.Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+ loading capacity and promotes apoptosis.The therapeutic potential of modulating the ceramide/sphingomyelin pathwayApoptotic sphingolipid ceramide in cancer therapy.Molecular cloning and characterization of OsCDase, a ceramidase enzyme from rice.The development of aggressive cancer: a possible role for sphingolipids.A method for visualization of "omic" datasets for sphingolipid metabolism to predict potentially interesting differences.New advances on structural and biological functions of ceramide in apoptotic/necrotic cell death and cancer.Sphingosine, a product of ceramide hydrolysis, influences the formation of ceramide channels.Ceramide: second messenger or modulator of membrane structure and dynamics?Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA.
P2860
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P2860
Molecular cloning and characterization of a human mitochondrial ceramidase
description
2000 nî lūn-bûn
@nan
2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Molecular cloning and characterization of a human mitochondrial ceramidase
@ast
Molecular cloning and characterization of a human mitochondrial ceramidase
@en
Molecular cloning and characterization of a human mitochondrial ceramidase
@en-gb
Molecular cloning and characterization of a human mitochondrial ceramidase
@nl
type
label
Molecular cloning and characterization of a human mitochondrial ceramidase
@ast
Molecular cloning and characterization of a human mitochondrial ceramidase
@en
Molecular cloning and characterization of a human mitochondrial ceramidase
@en-gb
Molecular cloning and characterization of a human mitochondrial ceramidase
@nl
prefLabel
Molecular cloning and characterization of a human mitochondrial ceramidase
@ast
Molecular cloning and characterization of a human mitochondrial ceramidase
@en
Molecular cloning and characterization of a human mitochondrial ceramidase
@en-gb
Molecular cloning and characterization of a human mitochondrial ceramidase
@nl
P2093
P921
P3181
P356
P1476
Molecular cloning and characterization of a human mitochondrial ceramidase
@en
P2093
P304
P3181
P356
10.1074/JBC.M002522200
P407
P577
2000-07-14T00:00:00Z