Compromised HOXA5 function can limit p53 expression in human breast tumours
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HOXA5 regulates expression of the progesterone receptorHIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cellsHOXA5 regulates hMLH1 expression in breast cancer cellsProtein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damageRegulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5The homeobox gene GAX activates p21WAF1/CIP1 expression in vascular endothelial cells through direct interaction with upstream AT-rich sequencesHOXA5-twist interaction alters p53 homeostasis in breast cancer cellsHomeodomain protein DLX4 counteracts key transcriptional control mechanisms of the TGF-β cytostatic program and blocks the antiproliferative effect of TGF-βHoxa 11 is upstream of Integrin alpha8 expression in the developing kidney.The HOX homeodomain proteins block CBP histone acetyltransferase activityHOXA5-induced apoptosis in breast cancer cells is mediated by caspases 2 and 8Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasisDifferential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1Unique molecular characteristics of pediatric myxopapillary ependymomaHOXB13 promotes ovarian cancer progressionAltered HOX and WNT7A expression in human lung cancerIncreased islet apoptosis in Pdx1+/- miceUterine receptivity and implantation: the regulation and action of insulin-like growth factor binding protein-1 (IGFBP-1), HOXA10 and forkhead transcription factor-1 (FOXO-1) in the baboon endometriumThe p53 pathway in breast cancerCorrelation of expression of BP1, a homeobox gene, with estrogen receptor status in breast cancerGene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts.Human HOX gene mutationsHuman securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosisHOXB4 homeodomain protein is expressed in developing epidermis and skin disorders and modulates keratinocyte proliferationHuman growth hormone-regulated HOXA1 is a human mammary epithelial oncogeneHoxA5 stabilizes adherens junctions via increased Akt1Rare and frequent promoter methylation, respectively, of TSHZ2 and 3 genes that are both downregulated in expression in breast and prostate cancersAblation of PRMT6 reveals a role as a negative transcriptional regulator of the p53 tumor suppressorRegulation of p53 by Mdm2 E3 ligase function is dispensable in embryogenesis and development, but essential in response to DNA damageThe Y-box-binding protein, YB1, is a potential negative regulator of the p53 tumor suppressorIdentification of Akt interaction protein PHF20/TZP that transcriptionally regulates p53VentX trans-activates p53 and p16ink4a to regulate cellular senescenceThe loss of Hoxa5 function causes estrous acyclicity and ovarian epithelial inclusion cysts.Transcriptional profiling of mammary gland side population cells.Dissecting microregulation of a master regulatory network.DNA hypermethylation and clinicopathological features in breast cancer: the Western New York Exposures and Breast Cancer (WEB) Study.Cancer genomics identifies regulatory gene networks associated with the transition from dysplasia to advanced lung adenocarcinomas induced by c-Raf-1.Influence of Hoxa5 on p53 tumorigenic outcome in mice.Hox specificity unique roles for cofactors and collaborators.Autoantibodies to tumor-associated antigens in epithelial ovarian carcinoma.
P2860
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P2860
Compromised HOXA5 function can limit p53 expression in human breast tumours
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2000 թվականի հունիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
Compromised HOXA5 function can limit p53 expression in human breast tumours
@ast
Compromised HOXA5 function can limit p53 expression in human breast tumours
@en
Compromised HOXA5 function can limit p53 expression in human breast tumours
@en-gb
Compromised HOXA5 function can limit p53 expression in human breast tumours
@nl
type
label
Compromised HOXA5 function can limit p53 expression in human breast tumours
@ast
Compromised HOXA5 function can limit p53 expression in human breast tumours
@en
Compromised HOXA5 function can limit p53 expression in human breast tumours
@en-gb
Compromised HOXA5 function can limit p53 expression in human breast tumours
@nl
prefLabel
Compromised HOXA5 function can limit p53 expression in human breast tumours
@ast
Compromised HOXA5 function can limit p53 expression in human breast tumours
@en
Compromised HOXA5 function can limit p53 expression in human breast tumours
@en-gb
Compromised HOXA5 function can limit p53 expression in human breast tumours
@nl
P2093
P2860
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P1476
Compromised HOXA5 function can limit p53 expression in human breast tumours
@en
P2093
S A Martensen
W F Odenwald
P2860
P2888
P3181
P356
10.1038/35016125
P407
P577
2000-06-22T00:00:00Z
P5875
P6179
1045061122