Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy
about
The serine/threonine kinases SGK2 and SGK3 are potent stimulators of the epithelial Na+ channel alpha,beta,gamma-ENaCSerum and Glucocorticoid Regulated Kinase 1 in Sodium HomeostasisGlucocorticoid activation of Na(+)/H(+) exchanger isoform 3 revisited. The roles of SGK1 and NHERF2Serum/glucocorticoid-inducible kinase can phosphorylate the cyclic AMP response element binding protein, CREB.Plasma corticosterone activates SGK1 and induces morphological changes in oligodendrocytes in corpus callosum.Genetic variation in aldosterone synthase predicts plasma glucose levels.Regulation of renal tubular glucose reabsorption by Akt2/PKBβImpaired renal Na(+) retention in the sgk1-knockout mouse.Expression of ENaC and serum- and glucocorticoid-induced kinase 1 in the rat intestinal epithelium.Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1.Haemodynamics in microvascular complications in type 1 diabetes.Angiotensin II mediates cell survival through upregulation and activation of the serum and glucocorticoid inducible kinase 1.Transcription factor NF-κB regulates expression of pore-forming Ca2+ channel unit, Orai1, and its activator, STIM1, to control Ca2+ entry and affect cellular functions.Role of Sgk1 in salt and potassium homeostasis.Transforming growth factor beta contributes to progressive diabetic nephropathyMechanisms of regulation of epithelial sodium channel by SGK1 in A6 cells.Circulating transforming growth factor-beta1 levels and the risk for kidney disease in African Americans.Heterocyclic indazole derivatives as SGK1 inhibitors, WO2008138448.SGK1-sensitive renal tubular glucose reabsorption in diabetes.Stimulation of Ca2+-channel Orai1/STIM1 by serum- and glucocorticoid-inducible kinase 1 (SGK1).The Western-style diet: a major risk factor for impaired kidney function and chronic kidney disease.Serum- and glucocorticoid-inducible kinase 1 in the regulation of renal and extrarenal potassium transport.Aldosterone stimulates nuclear factor-kappa B activity and transcription of intercellular adhesion molecule-1 and connective tissue growth factor in rat mesangial cells via serum- and glucocorticoid-inducible protein kinase-1.Pathophysiology of the diabetic kidney.Relevance of SGK1 in structural, functional and molecular alterations produced by aldosterone in heart.Sodium chloride, SGK1, and Th17 activation.Strategic attack on host cell gene expression during adenovirus infection.Disturbance of oligodendrocyte function plays a key role in the pathogenesis of schizophrenia and major depressive disorder.Aldosterone-stimulated SGK1 activity mediates profibrotic signaling in the mesangium.Sodium glucose cotransporter SGLT1 as a therapeutic target in diabetes mellitus.The impact of insulin resistance on the kidney and vasculature.Functional expression of TRPV4 channels in human collecting duct cells: implications for secondary hypertension in diabetic nephropathy.Ubiquitin-proteasome degradation of serum- and glucocorticoid-regulated kinase-1 (SGK-1) is mediated by the chaperone-dependent E3 ligase CHIPMineralocorticoid receptor blockade ameliorates peritoneal fibrosis in new rat peritonitis model.SGK1-dependent upregulation of connective tissue growth factor by angiotensin II.Differential regulation of serum- and glucocorticoid-inducible kinase 1 (SGK1) splice variants based on alternative initiation of transcription.Subcellular location of serum- and glucocorticoid-induced kinase-1 in renal and mammary epithelial cells.Impaired intestinal NHE3 activity in the PDK1 hypomorphic mouse.DOCA-induced phosphorylation of glycogen synthase kinase 3beta.SGK1 activates Na+-K+-ATPase in amphibian renal epithelial cells.
P2860
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P2860
Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy
description
2000 nî lūn-bûn
@nan
2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Deranged transcriptional regul ...... e hSGK in diabetic nephropathy
@ast
Deranged transcriptional regul ...... e hSGK in diabetic nephropathy
@en
Deranged transcriptional regul ...... e hSGK in diabetic nephropathy
@en-gb
Deranged transcriptional regul ...... e hSGK in diabetic nephropathy
@nl
type
label
Deranged transcriptional regul ...... e hSGK in diabetic nephropathy
@ast
Deranged transcriptional regul ...... e hSGK in diabetic nephropathy
@en
Deranged transcriptional regul ...... e hSGK in diabetic nephropathy
@en-gb
Deranged transcriptional regul ...... e hSGK in diabetic nephropathy
@nl
prefLabel
Deranged transcriptional regul ...... e hSGK in diabetic nephropathy
@ast
Deranged transcriptional regul ...... e hSGK in diabetic nephropathy
@en
Deranged transcriptional regul ...... e hSGK in diabetic nephropathy
@en-gb
Deranged transcriptional regul ...... e hSGK in diabetic nephropathy
@nl
P2093
P2860
P50
P3181
P356
P1476
Deranged transcriptional regul ...... e hSGK in diabetic nephropathy
@en
P2093
B Friedrich
C A Wagner
M Lanzendorfer
M Paulmichl
P2860
P304
P3181
P356
10.1073/PNAS.97.14.8157
P407
P577
2000-07-01T00:00:00Z