Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12
about
The ciliary neurotrophic factor receptor alpha component induces the secretion of and is required for functional responses to cardiotrophin-like cytokineThe structure of interleukin-23 reveals the molecular basis of p40 subunit sharing with interleukin-12Cloning and characterization of deer mouse (Peromyscus maniculatus) cytokine and chemokine cDNAsHydrogen/deuterium exchange mass spectrometry applied to IL-23 interaction characteristics: potential impact for therapeuticsInterleukin-23: as a drug target for autoimmune inflammatory diseasesStructure of the extracellular domains of the human interleukin-6 receptor alpha -chainCrystal Structure of the interleukin-15.interleukin-15 receptor alpha complex: insights into trans and cis presentationEllman's reagent in promoting crystallization and structure determination of Anabaena CcbPStructural basis of interleukin-5 dimer recognition by its α receptorGPL, a novel cytokine receptor related to GP130 and leukemia inhibitory factor receptorCharacterization of the interaction between interleukin-13 and interleukin-13 receptorsEfficient production and purification of recombinant human interleukin-12 (IL-12) overexpressed in mammalian cells without affinity tagThe metallopeptide antibiotic bacitracin inhibits interleukin-12 alphabeta and beta2 secretion.Optimized expression and specific activity of IL-12 by directed molecular evolution.Expression, engineering and characterization of the tumor-targeting heterodimeric immunocytokine F8-IL12.Free IL-12p40 monomer is a polyfunctional adaptor for generating novel IL-12-like heterodimers extracellularlyModulation of Interleukin-12 activity in the presence of heparinThe role of interchain heterodisulfide formation in activation of the human common beta and mouse betaIL-3 receptors.IL-12 family cytokines: immunological playmakersDiscovery and mechanism of ustekinumab: a human monoclonal antibody targeting interleukin-12 and interleukin-23 for treatment of immune-mediated disorders.IL-27 structural analysis demonstrates similarities with ciliary neurotrophic factor (CNTF) and leads to the identification of antagonistic variantsNetCGlyc 1.0: prediction of mammalian C-mannosylation sites.Molecular immunity to mycobacteria: knowledge from the mutation and phenotype spectrum analysis of Mendelian susceptibility to mycobacterial diseases.Novel immunocytokine IL12-SS1 (Fv) inhibits mesothelioma tumor growth in nude mice.Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genesRecombinant p35 from bacteria can form Interleukin (IL-)12, but Not IL-35IL12B expression is sustained by a heterogenous population of myeloid lineages during tuberculosis.Inhibiting cytokines of the interleukin-12 family: recent advances and novel challenges.Optimization of canine interleukin-12 production using a baculovirus insect cell expression system.Distinct subunit pairing criteria within the heterodimeric IL-12 cytokine family.Making many from few: IL-12p40 as a model for the combinatorial assembly of heterodimeric cytokines.Innate immune sensing of HIV-1 by dendritic cells.A polymorphism in the coding region of Il12b promotes IL-12p70 and IL-23 heterodimer formation.IL-12 delivered intratumorally by multilamellar liposomes reactivates memory T cells in human tumor microenvironments.Structural biology of shared cytokine receptors.Inherited interleukin-12 deficiency: IL12B genotype and clinical phenotype of 13 patients from six kindreds.Immunization with adenoviral vectors carrying recombinant IL-12 and E7 enhanced the antitumor immunity against human papillomavirus 16-associated tumor.Different tissue distribution properties for glycosylation variants of fusion proteins containing the p40 subunit of murine interleukin-12.Molecular interactions within the IL-6/IL-12 cytokine/receptor superfamily.Ustekinumab : targeting the IL-17 pathway to improve outcomes in psoriatic arthritis.
P2860
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P2860
Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Charged residues dominate a un ...... imeric cytokine interleukin-12
@ast
Charged residues dominate a un ...... imeric cytokine interleukin-12
@en
Charged residues dominate a un ...... imeric cytokine interleukin-12
@en-gb
Charged residues dominate a un ...... imeric cytokine interleukin-12
@nl
type
label
Charged residues dominate a un ...... imeric cytokine interleukin-12
@ast
Charged residues dominate a un ...... imeric cytokine interleukin-12
@en
Charged residues dominate a un ...... imeric cytokine interleukin-12
@en-gb
Charged residues dominate a un ...... imeric cytokine interleukin-12
@nl
prefLabel
Charged residues dominate a un ...... imeric cytokine interleukin-12
@ast
Charged residues dominate a un ...... imeric cytokine interleukin-12
@en
Charged residues dominate a un ...... imeric cytokine interleukin-12
@en-gb
Charged residues dominate a un ...... imeric cytokine interleukin-12
@nl
P2093
P2860
P356
P1433
P1476
Charged residues dominate a un ...... imeric cytokine interleukin-12
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/19.14.3530
P407
P577
2000-07-17T00:00:00Z