What the structure of a calcium pump tells us about its mechanism
about
Structural changes in the calcium pump accompanying the dissociation of calciumCalcium binding and allosteric signaling mechanisms for the sarcoplasmic reticulum Ca²+ ATPase.Hyperactivation of the human plasma membrane Ca2+ pump PMCA h4xb by mutation of Glu99 to Lys.Crystal structure of D351A and P312A mutant forms of the mammalian sarcoplasmic reticulum Ca(2+) -ATPase reveals key events in phosphorylation and Ca(2+) release.Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 1 and 2 isoforms and characterization of Darier disease (SERCA2) mutants by steady-state and transient kinetic analyses.Involvement of the cytoplasmic loop L6-7 in the entry mechanism for transport of Ca2+ through the sarcoplasmic reticulum Ca2+-ATPase.Inhibition of SERCA Ca2+ pumps by 2-aminoethoxydiphenyl borate (2-APB). 2-APB reduces both Ca2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca2+-binding sites.Mapping interactions between the Ca2+-ATPase and its substrate ATP with infrared spectroscopy.Effect of orthophosphate, nucleotide analogues, ADP, and phosphorylation on the cytoplasmic domains of Ca(2+)-ATPase from scallop sarcoplasmic reticulum.Importance of transmembrane segment M1 of the sarcoplasmic reticulum Ca2+-ATPase in Ca2+ occlusion and phosphoenzyme processing.Distinct natures of beryllium fluoride-bound, aluminum fluoride-bound, and magnesium fluoride-bound stable analogues of an ADP-insensitive phosphoenzyme intermediate of sarcoplasmic reticulum Ca2+-ATPase: changes in catalytic and transport sites durP-O bond destabilization accelerates phosphoenzyme hydrolysis of sarcoplasmic reticulum Ca2+ -ATPase.Evidence calcium pump binds magnesium before inorganic phosphate.A systematic mutagenesis study of Ile-282 in transmembrane segment M4 of the plasma membrane H+-ATPase.
P2860
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P2860
What the structure of a calcium pump tells us about its mechanism
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2001 nî lūn-bûn
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2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2001 թվականի հունիսին հրատարակված գիտական հոդված
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2001年の論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年论文
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What the structure of a calcium pump tells us about its mechanism
@ast
What the structure of a calcium pump tells us about its mechanism
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What the structure of a calcium pump tells us about its mechanism
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label
What the structure of a calcium pump tells us about its mechanism
@ast
What the structure of a calcium pump tells us about its mechanism
@en
What the structure of a calcium pump tells us about its mechanism
@en-gb
prefLabel
What the structure of a calcium pump tells us about its mechanism
@ast
What the structure of a calcium pump tells us about its mechanism
@en
What the structure of a calcium pump tells us about its mechanism
@en-gb
P1433
P1476
What the structure of a calcium pump tells us about its mechanism
@en
P2093
Anthony G. LEE
J. Malcolm EAST
P356
10.1042/0264-6021:3560665
P407
P577
2001-06-15T00:00:00Z