Peptides from the amino terminal mdm-2-binding domain of p53, designed from conformational analysis, are selectively cytotoxic to transformed cells
about
Anticancer peptide PNC-27 adopts an HDM-2-binding conformation and kills cancer cells by binding to HDM-2 in their membranesPreferential induction of necrosis in human breast cancer cells by a p53 peptide derived from the MDM2 binding siteApamin as a novel template for structure-based rational design of potent peptide activators of p53D-peptide inhibitors of the p53–MDM2 interaction for targeted molecular therapy of malignant neoplasmsDesign and implementation of a high yield production system for recombinant expression of peptidesmRNA Display Selection of an Optimized MDM2-Binding Peptide That Potently Inhibits MDM2-p53 InteractionBacterial redox protein azurin, tumor suppressor protein p53, and regression of cancer.Effects of dendritic cells transfected with full-length wild-type p53 and stimulated by gastric cancer lysates on immune responseNT4(Si)-p53(N15)-antennapedia induces cell death in a human hepatocellular carcinoma cell lineNovel peptides from the RAS-p21 and p53 proteins for the treatment of cancerChondroitin Sulfate as a Molecular Portal That Preferentially Mediates the Apoptotic Killing of Tumor Cells by Penetratin-directed Mitochondria-disrupting PeptidesEvaluation of the use of therapeutic peptides for cancer treatmentSmall molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors.Peptide aptamers: recent developments for cancer therapy.Inhibiting the p53-MDM2 interaction: an important target for cancer therapy.Therapeutic peptides for cancer therapy. Part I - peptide inhibitors of signal transduction cascades.Secretory expression of p53(N15)-Ant following lentivirus-mediated gene transfer induces cell death in human cancer cells.Cellular uptake of exogenous human PDCD5 protein.Differential regulation of cardiomyocyte survival and hypertrophy by MDM2, an E3 ubiquitin ligase.Trans-membrane peptide therapy for malignant glioma by use of a peptide derived from the MDM2 binding site of p53.Production of cell-penetrating peptides in Escherichia coli using an intein-mediated system.The anticancer peptide RT53 induces immunogenic cell death
P2860
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P2860
Peptides from the amino terminal mdm-2-binding domain of p53, designed from conformational analysis, are selectively cytotoxic to transformed cells
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Peptides from the amino termin ...... cytotoxic to transformed cells
@ast
Peptides from the amino termin ...... cytotoxic to transformed cells
@en
Peptides from the amino termin ...... cytotoxic to transformed cells
@en-gb
Peptides from the amino termin ...... cytotoxic to transformed cells
@nl
type
label
Peptides from the amino termin ...... cytotoxic to transformed cells
@ast
Peptides from the amino termin ...... cytotoxic to transformed cells
@en
Peptides from the amino termin ...... cytotoxic to transformed cells
@en-gb
Peptides from the amino termin ...... cytotoxic to transformed cells
@nl
prefLabel
Peptides from the amino termin ...... cytotoxic to transformed cells
@ast
Peptides from the amino termin ...... cytotoxic to transformed cells
@en
Peptides from the amino termin ...... cytotoxic to transformed cells
@en-gb
Peptides from the amino termin ...... cytotoxic to transformed cells
@nl
P2093
P2860
P356
P1476
Peptides from the amino termin ...... cytotoxic to transformed cells
@en
P2093
F K Friedman
M Kanovsky
M R Pincus
P Rubinstein
P W Brandt-Rauf
P2860
P2880
P304
P356
10.1073/PNAS.211280698
P407
P577
2001-10-23T00:00:00Z