Xenobiotic-activated receptors: from transcription to drug metabolism to disease
about
Overview of AHR functional domains and the classical AHR signaling pathway: induction of drug-metabolizing enzymesMolecular basis of electrophilic and oxidative defense: promises and perils of Nrf2Role of Nrf2 in oxidative stress and toxicityInfluence of light on aryl hydrocarbon receptor signaling and consequences in drug metabolism, physiology and diseaseInduction of metallothionein I by arsenic via metal-activated transcription factor 1. Critical role of c-terminal cysteine residues in arsenic sensingCritical cysteine residues of Kelch-like ECH-associated protein 1 in arsenic sensing and suppression of nuclear factor erythroid 2-related factor 2Resveratrol inhibits paraquat-induced oxidative stress and fibrogenic response by activating the Nrf2 pathwayNRF2 cysteine residues are critical for oxidant/electrophile-sensing, Kelch-like ECH-associated protein-1-dependent ubiquitination-proteasomal degradation, and transcription activationRedox regulation by Nrf2: gatekeeping for the basal and diabetes-induced expression of thioredoxin interacting proteinDisruption of Nrf2 synergizes with high glucose to cause heightened myocardial oxidative stress and severe cardiomyopathy in diabetic miceScreen Identifying Arabidopsis Transcription Factors Involved in the Response to 9-Lipoxygenase-Derived OxylipinsTranscriptomic assessment of resistance to effects of an aryl hydrocarbon receptor (AHR) agonist in embryos of Atlantic killifish (Fundulus heteroclitus) from a marine Superfund site.Drug metabolism and clearance system in tumor cells of patients with multiple myelomaA comparative proteomic study identified LRPPRC and MCM7 as putative actors in imatinib mesylate cross-resistance in Lucena cell line.Isoform-Specific Regulation of Mouse Carboxylesterase Expression and Activity by Prototypical Transcriptional Activators.Role of xenobiotic metabolism in cancer: involvement of transcriptional and miRNA regulation of P450s.Role of microRNAs in the regulation of drug metabolizing and transporting genes and the response to environmental toxicants.Nuclear receptors in the cross-talk of drug metabolism and inflammation.Increased protein oxidation and decreased expression of nuclear factor E2-related factor 2 protein in skin tissue of patients with diabetes.Are structural analogues to bisphenol a safe alternatives?Effect of aflatoxin B1 on nuclear receptors PXR, CAR, and AhR and their target cytochromes P450 mRNA expression in primary cultures of human hepatocytes.Ochratoxin A induces CYP3A4, 2B6, 3A5, 2C9, 1A1, and CYP1A2 gene expression in primary cultured human hepatocytes: a possible activation of nuclear receptors.Systematic target function annotation of human transcription factors.Protective Effect of Boswellic Acids against Doxorubicin-Induced Hepatotoxicity: Impact on Nrf2/HO-1 Defense Pathway.
P2860
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P2860
Xenobiotic-activated receptors: from transcription to drug metabolism to disease
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Xenobiotic-Activated Receptors: From Transcription to Drug Metabolism to Disease
@nl
Xenobiotic-activated receptors: from transcription to drug metabolism to disease
@ast
Xenobiotic-activated receptors: from transcription to drug metabolism to disease
@en
Xenobiotic-activated receptors: from transcription to drug metabolism to disease
@en-gb
type
label
Xenobiotic-Activated Receptors: From Transcription to Drug Metabolism to Disease
@nl
Xenobiotic-activated receptors: from transcription to drug metabolism to disease
@ast
Xenobiotic-activated receptors: from transcription to drug metabolism to disease
@en
Xenobiotic-activated receptors: from transcription to drug metabolism to disease
@en-gb
prefLabel
Xenobiotic-Activated Receptors: From Transcription to Drug Metabolism to Disease
@nl
Xenobiotic-activated receptors: from transcription to drug metabolism to disease
@ast
Xenobiotic-activated receptors: from transcription to drug metabolism to disease
@en
Xenobiotic-activated receptors: from transcription to drug metabolism to disease
@en-gb
P921
P3181
P356
P1476
Xenobiotic-activated receptors: from transcription to drug metabolism to disease
@en
P2880
P304
P3181
P356
10.1021/TX800156S
P50
P577
2008-09-15T00:00:00Z