The transcription factor p53: not a repressor, solely an activator
about
A Long Noncoding RNA Regulates Sister Chromatid CohesionThe p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genesHuman papilloma virus E7 oncoprotein abrogates the p53-p21-DREAM pathway.p53-Regulated Networks of Protein, mRNA, miRNA, and lncRNA Expression Revealed by Integrated Pulsed Stable Isotope Labeling With Amino Acids in Cell Culture (pSILAC) and Next Generation Sequencing (NGS) Analysesp53 attenuates AKT signaling by modulating membrane phospholipid compositionIntegration of TP53, DREAM, MMB-FOXM1 and RB-E2F target gene analyses identifies cell cycle gene regulatory networks.Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis.Is p53 Involved in Tissue-Specific Insulin Resistance Formation?Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex.Census and evaluation of p53 target genes.Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control.Promoter SNPs rs116896264 and rs73933062 form a distinct haplotype and are associated with galectin-4 overexpression in colorectal cancer.Genome-wide analysis of p53 transcriptional programs in B cells upon exposure to genotoxic stress in vivoIdentification of a p53-repressed gene module in breast cancer cells.Retrotransposon-derived p53 binding sites enhance telomere maintenance and genome protection.p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells.CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress.Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activityp21 governs p53's repressive side.Simplify p53: just an activator.p53 pulses lead to distinct patterns of gene expression albeit similar DNA-binding dynamics.Different molecular complexes that mediate transcriptional induction and repression by FoxP3.Stopping cells from dividing.p53 is essential for DNA methylation homeostasis in naïve embryonic stem cells, and its loss promotes clonal heterogeneity.Timing of transcription during the cell cycle: Protein complexes binding to E2F, E2F/CLE, CDE/CHR, or CHR promoter elements define early and late cell cycle gene expression.Cell cycle arrest through indirect transcriptional repression by p53: I have a DREAM.Mechanisms of transcriptional regulation by p53.Diverse p53/DNA binding modes expand the repertoire of p53 response elements.Cell cycle transcription control: DREAM/MuvB and RB-E2F complexes.p53 and Mdm2 act synergistically to maintain cardiac homeostasis and mediate cardiomyocyte cell cycle arrest through a network of microRNAs.TBP-like Protein (TLP) Disrupts the p53-MDM2 Interaction and Induces Long-lasting p53 Activation.Revealing a human p53 universe
P2860
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P2860
The transcription factor p53: not a repressor, solely an activator
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2014年の論文
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The transcription factor p53: not a repressor, solely an activator
@ast
The transcription factor p53: not a repressor, solely an activator
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The transcription factor p53: not a repressor, solely an activator
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The transcription factor p53: not a repressor, solely an activator
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The transcription factor p53: not a repressor, solely an activator
@ast
The transcription factor p53: not a repressor, solely an activator
@en
The transcription factor p53: not a repressor, solely an activator
@en-gb
The transcription factor p53: not a repressor, solely an activator
@nl
prefLabel
The transcription factor p53: not a repressor, solely an activator
@ast
The transcription factor p53: not a repressor, solely an activator
@en
The transcription factor p53: not a repressor, solely an activator
@en-gb
The transcription factor p53: not a repressor, solely an activator
@nl
P2860
P3181
P1433
P1476
The transcription factor p53: not a repressor, solely an activator
@en
P2093
Lydia Steiner
P2860
P304
P3181
P356
10.4161/15384101.2014.949083
P407
P577
2014-01-01T00:00:00Z