Identification of protein-tyrosine phosphatase 1B as the major tyrosine phosphatase activity capable of dephosphorylating and activating c-Src in several human breast cancer cell lines
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The role of protein elongation factor eEF1A2 in ovarian cancerSelective regulation of tumor necrosis factor-induced Erk signaling by Src family kinases and the T cell protein tyrosine phosphatasePhosphorylated alpha-actinin and protein-tyrosine phosphatase 1B coregulate the disassembly of the focal adhesion kinase x Src complex and promote cell migrationInteraction of protein tyrosine phosphatase (PTP) 1B with its substrates is influenced by two distinct binding domainsH2S-Induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress responseThe role of protein-tyrosine phosphatase 1B in integrin signalingThe tyrosine phosphatase 1B regulates linker for activation of T-cell phosphorylation and platelet aggregation upon FcgammaRIIa cross-linkingPTP1B regulates cortactin tyrosine phosphorylation by targeting Tyr446Differential regulation of endoplasmic reticulum stress by protein tyrosine phosphatase 1B and T cell protein tyrosine phosphataseThe role of protein tyrosine phosphatase 1B in Ras signalingSKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells.ER-bound protein tyrosine phosphatase PTP1B interacts with Src at the plasma membrane/substrate interfaceA novel role for protein tyrosine phosphatase 1B as a positive regulator of neuroinflammation.Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitorTargeting Inactive Enzyme Conformation: Aryl Diketoacid Derivatives as a New Class of PTP1B InhibitorsRegulation of SRC family kinases in human cancersMUC1 cytoplasmic tail: a potential therapeutic target for ovarian carcinomaSpatiotemporal regulation of Src and its substrates at invadosomesA RNA interference screen identifies the protein phosphatase 2A subunit PR55gamma as a stress-sensitive inhibitor of c-SRCProtein tyrosine phosphatase, PTP1B, expression and activity in rat corneal endothelial cellsIdentification of YB-1 as a regulator of PTP1B expression: implications for regulation of insulin and cytokine signalingSimultaneous deactivation of FAK and Src improves the pathology of hypertrophic scarDivergent modulation of Src-family kinase regulatory interactions with ATP-competitive inhibitors.Protein tyrosine phosphatase UBASH3B is overexpressed in triple-negative breast cancer and promotes invasion and metastasis.A renaissance for SRCPTP1B triggers integrin-mediated repression of myosin activity and modulates cell contractility.Microtubule and cell contact dependency of ER-bound PTP1B localization in growth cones.Acquisition of a specific and potent PTP1B inhibitor from a novel combinatorial library and screening procedure.Acquisition of a potent and selective TC-PTP inhibitor via a stepwise fluorophore-tagged combinatorial synthesis and screening strategyTargeting PTPs with small molecule inhibitors in cancer treatmentProtein tyrosine phosphatase 1B expression contributes to the development of breast cancer.Protein profiling of isolated leukocytes, myofibroblasts, epithelial, Basal, and endothelial cells from normal, hyperplastic, cancerous, and inflammatory human prostate tissues.Substrate specificity of protein tyrosine phosphatases 1B, RPTPα, SHP-1, and SHP-2.Simultaneous siRNA targeting of Src and downstream signaling molecules inhibit tumor formation and metastasis of a human model breast cancer cell line.Identification of an IGF-1R kinase regulatory phosphatase using the fission yeast Schizosaccharomyces pombe and a GFP tagged IGF-1R in mammalian cells.Intracellular reactive oxygen species activate Src tyrosine kinase during cell adhesion and anchorage-dependent cell growthSRC: a century of science brought to the clinic.Disruption of protein-tyrosine phosphatase 1B expression in the pancreas affects β-cell function.Chimeric design, synthesis, and biological assays of a new nonpeptide insulin-mimetic vanadium compound to inhibit protein tyrosine phosphatase 1BCB₁ cannabinoid receptors promote maximal FAK catalytic activity by stimulating cooperative signaling between receptor tyrosine kinases and integrins in neuronal cells.
P2860
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P2860
Identification of protein-tyrosine phosphatase 1B as the major tyrosine phosphatase activity capable of dephosphorylating and activating c-Src in several human breast cancer cell lines
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2000 nî lūn-bûn
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2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
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2000年論文
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2000年论文
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name
Identification of protein-tyro ...... human breast cancer cell lines
@ast
Identification of protein-tyro ...... human breast cancer cell lines
@en
Identification of protein-tyro ...... human breast cancer cell lines
@en-gb
Identification of protein-tyro ...... human breast cancer cell lines
@nl
type
label
Identification of protein-tyro ...... human breast cancer cell lines
@ast
Identification of protein-tyro ...... human breast cancer cell lines
@en
Identification of protein-tyro ...... human breast cancer cell lines
@en-gb
Identification of protein-tyro ...... human breast cancer cell lines
@nl
prefLabel
Identification of protein-tyro ...... human breast cancer cell lines
@ast
Identification of protein-tyro ...... human breast cancer cell lines
@en
Identification of protein-tyro ...... human breast cancer cell lines
@en-gb
Identification of protein-tyro ...... human breast cancer cell lines
@nl
P2093
P2860
P3181
P356
P1476
Identification of protein-tyro ...... human breast cancer cell lines
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.M004852200
P407
P577
2000-12-29T00:00:00Z