The interaction of titin and alpha-actinin is controlled by a phospholipid-regulated intramolecular pseudoligand mechanism
about
Nesprin-1alpha self-associates and binds directly to emerin and lamin A in vitroThe structure and regulation of human muscle α-actininMolecular mechanics of the alpha-actinin rod domain: bending, torsional, and extensional behaviorOpening of tandem calponin homology domains regulates their affinity for F-actin.Solution scattering suggests cross-linking function of telethonin in the complex with titinNovel structures for alpha-actinin:F-actin interactions and their implications for actin-membrane attachment and tension sensing in the cytoskeletonThe carboxyterminal EF domain of erythroid alpha-spectrin is necessary for optimal spectrin-actin bindingCapZ dynamics are altered by endothelin-1 and phenylephrine via PIP2- and PKC-dependent mechanisms.The actinin family of actin cross-linking proteins - a genetic perspective.Congenital macrothrombocytopenia-linked mutations in the actin-binding domain of α-actinin-1 enhance F-actin association.Recognition of intermolecular G-quadruplexes by full length nucleophosmin. Effect of a leukaemia-associated mutation.The ZASP-like motif in actinin-associated LIM protein is required for interaction with the alpha-actinin rod and for targeting to the muscle Z-line.Muscle giants: molecular scaffolds in sarcomerogenesis.Cytoskeletal regulation: rich in lipids.Smooth muscle titin Zq domain interaction with the smooth muscle alpha-actinin central rodCytoplasmic Ig-domain proteins: cytoskeletal regulators with a role in human diseaseMechanical stress-induced sarcomere assembly for cardiac muscle growth in length and width.Spectrin and phospholipids - the current picture of their fascinating interplay.Structural insights into Ca2+-calmodulin regulation of Plectin 1a-integrin β4 interaction in hemidesmosomes.Phosphoinositide binding to the substrate regulates susceptibility to proteolysis by calpain.Structural characterization of the interactions between palladin and α-actininMissing-in-metastasis and IRSp53 deform PI(4,5)P2-rich membranes by an inverse BAR domain-like mechanism.The Structurally Plastic CH2 Domain Is Linked to Distinct Functions of Fimbrins/Plastins.Conformational plasticity and evolutionary analysis of the myotilin tandem Ig domains.Limited digestion of α-actinin in the presence of F-actinModeling the assembly of the multiple domains of α-actinin-4 and its role in actin cross-linking.Phosphoinositides differentially regulate alpha-actinin flexibility and functionHypertrophic cardiomyopathy mutations in the calponin-homology domain of ACTN2 affect actin binding and cardiomyocyte Z-disc incorporation.Phosphoinositide binding regulates alpha-actinin CH2 domain structure: analysis by hydrogen/deuterium exchange mass spectrometry.α-Actinin/titin interaction: A dynamic and mechanically stable cluster of bonds in the muscle Z-disk.Conformational stabilization as a strategy to prevent nucleophosmin mislocalization in leukemia.Expression patterns of sarcomeric α-actin, α-actinin and UCP2 in the myocardium of Kunming mice after exposure to c-terminal polypeptide of cardiotrophin-1.
P2860
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P2860
The interaction of titin and alpha-actinin is controlled by a phospholipid-regulated intramolecular pseudoligand mechanism
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
The interaction of titin and a ...... lecular pseudoligand mechanism
@ast
The interaction of titin and a ...... lecular pseudoligand mechanism
@en
The interaction of titin and a ...... lecular pseudoligand mechanism
@en-gb
The interaction of titin and a ...... lecular pseudoligand mechanism
@nl
type
label
The interaction of titin and a ...... lecular pseudoligand mechanism
@ast
The interaction of titin and a ...... lecular pseudoligand mechanism
@en
The interaction of titin and a ...... lecular pseudoligand mechanism
@en-gb
The interaction of titin and a ...... lecular pseudoligand mechanism
@nl
prefLabel
The interaction of titin and a ...... lecular pseudoligand mechanism
@ast
The interaction of titin and a ...... lecular pseudoligand mechanism
@en
The interaction of titin and a ...... lecular pseudoligand mechanism
@en-gb
The interaction of titin and a ...... lecular pseudoligand mechanism
@nl
P2860
P356
P1433
P1476
The interaction of titin and a ...... lecular pseudoligand mechanism
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/19.23.6331
P407
P577
2000-12-01T00:00:00Z