Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation
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IFITM proteins restrict viral membrane hemifusion.Hyaluronidase 2 negatively regulates RON receptor tyrosine kinase and mediates transformation of epithelial cells by jaagsiekte sheep retrovirusHYAL1 overexpression is correlated with the malignant behavior of human breast cancerExpression and cellular localization of human hyaluronidase-2 in articular chondrocytes and cultured cell linesTransforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1Hyaluronidase expression and activity is regulated by pro-inflammatory cytokines in human airway epithelial cellsUpregulation of HYAL1 expression in breast cancer promoted tumor cell proliferation, migration, invasion and angiogenesisReactive oxygen species and hyaluronidase 2 regulate airway epithelial hyaluronan fragmentationHYAL1 and HYAL2 inhibit tumour growth in vivo but not in vitroKIAA1199, a deafness gene of unknown function, is a new hyaluronan binding protein involved in hyaluronan depolymerizationAmino acid residues that are important for Hyal2 function as a receptor for jaagsiekte sheep retrovirusRole of virus receptor Hyal2 in oncogenic transformation of rodent fibroblasts by sheep betaretrovirus env proteinsThe prostate cancer-associated human retrovirus XMRV lacks direct transforming activity but can induce low rates of transformation in cultured cellsTransformation and scattering activities of the receptor tyrosine kinase RON/Stk in rodent fibroblasts and lack of regulation by the jaagsiekte sheep retrovirus receptor, Hyal2Transforming growth factor-beta1 blocks the enhancement of tumor necrosis factor cytotoxicity by hyaluronidase Hyal-2 in L929 fibroblasts.Roles of Proteoglycans and Glycosaminoglycans in Wound Healing and FibrosisBaton pass hypothesis: successive incorporation of unconserved endogenous retroviral genes for placentation during mammalian evolutionReceptor Binding and Low pH Coactivate Oncogenic Retrovirus Envelope-Mediated FusionHYAL-2-WWOX-SMAD4 Signaling in Cell Death and Anticancer ResponseOvine pulmonary adenocarcinoma: a large animal model for human lung cancerCharacterization of the murine hyaluronidase gene region reveals complex organization and cotranscription of Hyal1 with downstream genes, Fus2 and Hyal3Expression of the jaagsiekte sheep retrovirus envelope glycoprotein is sufficient to induce lung tumors in sheepCoevolution of endogenous betaretroviruses of sheep and their hostProfessional exposure to goats increases the risk of pneumonic-type lung adenocarcinoma: results of the IFCT-0504-Epidemio studyThe effect of hyaluronic acid size and concentration on branching morphogenesis and tubule differentiation in developing kidney culture systems: potential applications to engineering of renal tissuesMouse testicular hyaluronidase-like proteins SPAM1 and HYAL5 but not HYALP1 degrade hyaluronanIdentification of amino acid residues required for the substrate specificity of human and mouse chondroitin sulfate hydrolase (conventional hyaluronidase-4)Friendly viruses: the special relationship between endogenous retroviruses and their hostEndogenous retroviruses in trophoblast differentiation and placental developmentApplication of next generation sequencing in mammalian embryogenomics: lessons learned from endogenous betaretroviruses of sheepA paradigm for virus-host coevolution: sequential counter-adaptations between endogenous and exogenous retrovirusesA mammalian homolog of the zebrafish transmembrane protein 2 (TMEM2) is the long-sought-after cell-surface hyaluronidaseJaagsiekte sheep retrovirus infects multiple cell types in the ovine lungHyaluronan Depolymerization by Megakaryocyte Hyaluronidase-2 Is Required for Thrombopoiesis.Jaagsiekte sheep retrovirus transformation in Madin-Darby canine kidney epithelial cell three-dimensional culture.Expression of endogenous betaretroviruses in the ovine uterus: effects of neonatal age, estrous cycle, pregnancy, and progesterone.Jaagsiekte sheep retrovirus Env protein stabilizes retrovirus vectors against inactivation by lung surfactant, centrifugation, and freeze-thaw cycling.Lung adenocarcinoma originates from retrovirus infection of proliferating type 2 pneumocytes during pulmonary post-natal development or tissue repairHyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2Retrovirus-induced ovine pulmonary adenocarcinoma, an animal model for lung cancer.
P2860
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P2860
Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation
description
2001 nî lūn-bûn
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2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年學術文章
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name
Candidate tumor suppressor HYA ...... iates oncogenic transformation
@ast
Candidate tumor suppressor HYA ...... iates oncogenic transformation
@en
Candidate tumor suppressor HYA ...... iates oncogenic transformation
@en-gb
Candidate tumor suppressor HYA ...... iates oncogenic transformation
@nl
type
label
Candidate tumor suppressor HYA ...... iates oncogenic transformation
@ast
Candidate tumor suppressor HYA ...... iates oncogenic transformation
@en
Candidate tumor suppressor HYA ...... iates oncogenic transformation
@en-gb
Candidate tumor suppressor HYA ...... iates oncogenic transformation
@nl
prefLabel
Candidate tumor suppressor HYA ...... iates oncogenic transformation
@ast
Candidate tumor suppressor HYA ...... iates oncogenic transformation
@en
Candidate tumor suppressor HYA ...... iates oncogenic transformation
@en-gb
Candidate tumor suppressor HYA ...... iates oncogenic transformation
@nl
P2093
P2860
P921
P356
P1476
Candidate tumor suppressor HYA ...... iates oncogenic transformation
@en
P2093
A Danilkovitch-Miagkova
M I Lerman
V Vigdorovich
P2860
P304
P356
10.1073/PNAS.071572898
P407
P577
2001-04-01T00:00:00Z