Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin
about
ELKS1 and Ca(2+) channel subunit β4 interact and colocalize at cerebellar synapsesA family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones.Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1The presynaptic active zone protein RIM1alpha is critical for normal learning and memory.The presynaptic active zoneRIM determines Ca²+ channel density and vesicle docking at the presynaptic active zoneRIM proteins activate vesicle priming by reversing autoinhibitory homodimerization of Munc13RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interactionCrystal structure of the RIM1alpha C2B domain at 1.7 A resolutionRIM1alpha and RIM1beta are synthesized from distinct promoters of the RIM1 gene to mediate differential but overlapping synaptic functionsRedundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter releaseMolecular mechanisms driving homeostatic plasticity of neurotransmitter releaseThe dynamic architecture of photoreceptor ribbon synapses: cytoskeletal, extracellular matrix, and intramembrane proteinsDistinct initial SNARE configurations underlying the diversity of exocytosisRab3-interacting molecules 2α and 2β promote the abundance of voltage-gated CaV1.3 Ca2+ channels at hair cell active zonesRim, a component of the presynaptic active zone and modulator of exocytosis, binds 14-3-3 through its N terminus.Molecular analysis of RIM1 in autosomal recessive Retinitis pigmentosaProtein mutated in paroxysmal dyskinesia interacts with the active zone protein RIM and suppresses synaptic vesicle exocytosisFragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel densityExome Analyses of Long QT Syndrome Reveal Candidate Pathogenic Mutations in Calmodulin-Interacting GenesRosuvastatin Treatment Affects Both Basal and Glucose-Induced Insulin Secretion in INS-1 832/13 CellsRab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channelsMolecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release sitePiccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP-GEFII.Rim2. Piccolo complex in cAMP-dependent exocytosisSNARE-driven, 25-millisecond vesicle fusion in vitro.Synaptotagmin-mediated vesicle fusion regulates cell migration.Ca2+ channel clustering with insulin-containing granules is disturbed in type 2 diabetesRab Interacting Molecules 2 and 3 Directly Interact with the Pore-Forming CaV1.3 Ca2+ Channel Subunit and Promote Its Membrane Expression.A de novo 1p34.2 microdeletion identifies the synaptic vesicle gene RIMS3 as a novel candidate for autismPKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis.Role of synaptotagmin in Ca2+-triggered exocytosis.Functional coupling of Rab3-interacting molecule 1 (RIM1) and L-type Ca2+ channels in insulin release.Rim1 modulates direct G-protein regulation of Ca(v)2.2 channels.What is the role of SNARE proteins in membrane fusion?Contact-induced clustering of syntaxin and munc18 docks secretory granules at the exocytosis site.Regulated exocytosis and SNARE function (Review).The active-zone protein Munc13 controls the use-dependence of presynaptic voltage-gated calcium channelsActive zones for presynaptic plasticity in the brain.Regulation of N-type voltage-gated calcium channels and presynaptic function by cyclin-dependent kinase 5.Fife organizes synaptic vesicles and calcium channels for high-probability neurotransmitter release
P2860
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P248
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P2860
Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin
description
2001 nî lūn-bûn
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2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Direct interaction of the Rab3 ...... ls, SNAP-25, and synaptotagmin
@ast
Direct interaction of the Rab3 ...... ls, SNAP-25, and synaptotagmin
@en
Direct interaction of the Rab3 ...... ls, SNAP-25, and synaptotagmin
@en-gb
Direct interaction of the Rab3 ...... ls, SNAP-25, and synaptotagmin
@nl
type
label
Direct interaction of the Rab3 ...... ls, SNAP-25, and synaptotagmin
@ast
Direct interaction of the Rab3 ...... ls, SNAP-25, and synaptotagmin
@en
Direct interaction of the Rab3 ...... ls, SNAP-25, and synaptotagmin
@en-gb
Direct interaction of the Rab3 ...... ls, SNAP-25, and synaptotagmin
@nl
prefLabel
Direct interaction of the Rab3 ...... ls, SNAP-25, and synaptotagmin
@ast
Direct interaction of the Rab3 ...... ls, SNAP-25, and synaptotagmin
@en
Direct interaction of the Rab3 ...... ls, SNAP-25, and synaptotagmin
@en-gb
Direct interaction of the Rab3 ...... ls, SNAP-25, and synaptotagmin
@nl
P2093
P2860
P921
P3181
P356
P1476
Direct interaction of the Rab3 ...... ls, SNAP-25, and synaptotagmin
@en
P2093
S Gattesco
S Magnin-Luthi
V Perret-Menoud
P2860
P304
P3181
P356
10.1074/JBC.M100929200
P407
P577
2001-08-31T00:00:00Z