TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression
about
Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeresThe telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182)Rap1 affects the length and heterogeneity of human telomeresThe formin-binding protein 17, FBP17, binds via a TNKS binding motif to tankyrase, a protein involved in telomere maintenanceInhibition of Epstein-Barr virus OriP function by tankyrase, a telomere-associated poly-ADP ribose polymerase that binds and modifies EBNA1Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1Functional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elongationNuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?Rickettsia Phylogenomics: Unwinding the Intricacies of Obligate Intracellular LifeCrystal structure of the catalytic fragment of murine poly(ADP-ribose) polymerase-2ADP-ribosyltransferases and poly ADP-ribosylationIdentification of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partnerTankyrase 1 interacts with Mcl-1 proteins and inhibits their regulation of apoptosisCentromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)atedGeneration and characterization of telomere length maintenance in tankyrase 2-deficient mice.Tankyrase 2 poly(ADP-ribose) polymerase domain-deleted mice exhibit growth defects but have normal telomere length and cappingVertebrate tankyrase domain structure and sterile alpha motif (SAM)-mediated multimerizationNuMA is a major acceptor of poly(ADP-ribosyl)ation by tankyrase 1 in mitosis.Natural and pharmacological regulation of telomeraseA novel form of the telomere-associated protein TIN2 localizes to the nuclear matrixIdentification of a novel murine pancreatic tumour antigen, which elicits antibody responses in patients with pancreatic carcinoma.Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging.PARP1 Is a TRF2-associated poly(ADP-ribose)polymerase and protects eroded telomeres.Telomeres, aging and cancer: in search of a happy ending.Many ways to telomere dysfunction: in vivo studies using mouse models.Telomere maintenance as a target for anticancer drug discovery.Telomeres and aging.Analysis of poly(ADP-Ribose) polymerases in Arabidopsis telomere biology.The Drosophila tankyrase regulates Wg signaling depending on the concentration of Daxin.Caspase Activation and Aberrant Cell Growth in a p53(+/+) Cell Line from a Li-Fraumeni Syndrome FamilyGene expression profiling of oral squamous cell carcinoma by differential display rt-PCR and identification of tumor biomarkers.Telomere-associated protein TIN2 is essential for early embryonic development through a telomerase-independent pathway.Telomeres, telomerase, and apoptosis.Targeted deletion reveals an essential function for the telomere length regulator Trf1.Poly(ADP-ribosylation) and genomic stability.Chromatin architecture and functions: the role(s) of poly(ADP-RIBOSE) polymerase and poly(ADPribosyl)ation of nuclear proteins.Functional interaction between poly(ADP-Ribose) polymerase 2 (PARP-2) and TRF2: PARP activity negatively regulates TRF2.Bloom syndrome cells undergo p53-dependent apoptosis and delayed assembly of BRCA1 and NBS1 repair complexes at stalled replication forks.The telomeric PARP, tankyrases, as targets for cancer therapyDNA repair and PARP in aging.
P2860
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P2860
TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
TANK2, a new TRF1-associated p ...... cell death upon overexpression
@ast
TANK2, a new TRF1-associated p ...... cell death upon overexpression
@en
TANK2, a new TRF1-associated p ...... cell death upon overexpression
@en-gb
TANK2, a new TRF1-associated p ...... cell death upon overexpression
@nl
type
label
TANK2, a new TRF1-associated p ...... cell death upon overexpression
@ast
TANK2, a new TRF1-associated p ...... cell death upon overexpression
@en
TANK2, a new TRF1-associated p ...... cell death upon overexpression
@en-gb
TANK2, a new TRF1-associated p ...... cell death upon overexpression
@nl
prefLabel
TANK2, a new TRF1-associated p ...... cell death upon overexpression
@ast
TANK2, a new TRF1-associated p ...... cell death upon overexpression
@en
TANK2, a new TRF1-associated p ...... cell death upon overexpression
@en-gb
TANK2, a new TRF1-associated p ...... cell death upon overexpression
@nl
P2093
P2860
P921
P356
P1476
TANK2, a new TRF1-associated p ...... cell death upon overexpression
@en
P2093
Kaminker PG
Zebarjadian Y
P2860
P304
35891-35899
P356
10.1074/JBC.M105968200
P407
P577
2001-07-13T00:00:00Z