Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1
about
An unappreciated role for RNA surveillanceCharacterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1.DEAD-box protein DDX3 associates with eIF4F to promote translation of selected mRNAsHypophosphorylated ASF/SF2 binds TAP and is present in messenger ribonucleoproteinsBiochemical analysis of the EJC reveals two new factors and a stable tetrameric protein coreDHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegansASAP, a novel protein complex involved in RNA processing and apoptosisDDX3 regulates cell growth through translational control of cyclin E1A novel mode of RBD-protein recognition in the Y14-Mago complexBinding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decayeIF4A3 is a novel component of the exon junction complexThe structure of the ASAP core complex reveals the existence of a Pinin-containing PSAP complexHuman DDX3 interacts with the HIV-1 Tat protein to facilitate viral mRNA translationThe DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational controlInteractions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathwaysNMD resulting from encephalomyocarditis virus IRES-directed translation initiation seems to be restricted to CBP80/20-bound mRNATwo mammalian MAGOH genes contribute to exon junction complex composition and nonsense-mediated decayFunctions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translationIdentification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay.A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decayAn unconventional human Ccr4-Caf1 deadenylase complex in nuclear cajal bodiesRibosomal protein S24 gene is mutated in Diamond-Blackfan anemiaComplexes between the nonsense-mediated mRNA decay pathway factor human upf1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa cellsMagoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex.The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling.RNA splicing capability of live neuronal dendritesSplicing enhances translation in mammalian cells: an additional function of the exon junction complexHuman RNPS1 and its associated factors: a versatile alternative pre-mRNA splicing regulator in vivoNuclear Pnn/DRS protein binds to spliced mRNPs and participates in mRNA processing and export via interaction with RNPS1Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathwaysStructure and function of the PWI motif: a novel nucleic acid-binding domain that facilitates pre-mRNA processingIntegration of splicing, transport and translation to achieve mRNA quality control by the nonsense-mediated decay pathway.A GFP-based reporter system to monitor nonsense-mediated mRNA decayMechanism and regulation of the nonsense-mediated decay pathwayPre-mRNA Splicing in Plants: In Vivo Functions of RNA-Binding Proteins Implicated in the Splicing ProcessNonsense-mediated mRNA decay: inter-individual variability and human diseaseCrystal structure of the Drosophila Mago nashi-Y14 complexMolecular insights into the interaction of PYM with the Mago-Y14 core of the exon junction complexCrystal structure of the human eIF4AIII-CWC22 complex shows how a DEAD-box protein is inhibited by a MIF4G domainNuclear import of Upf3p is mediated by importin-alpha/-beta and export to the cytoplasm is required for a functional nonsense-mediated mRNA decay pathway in yeast
P2860
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P248
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P2860
Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Communication of the position ...... machinery by the protein RNPS1
@ast
Communication of the position ...... machinery by the protein RNPS1
@en
Communication of the position ...... machinery by the protein RNPS1
@en-gb
Communication of the position ...... machinery by the protein RNPS1
@nl
type
label
Communication of the position ...... machinery by the protein RNPS1
@ast
Communication of the position ...... machinery by the protein RNPS1
@en
Communication of the position ...... machinery by the protein RNPS1
@en-gb
Communication of the position ...... machinery by the protein RNPS1
@nl
prefLabel
Communication of the position ...... machinery by the protein RNPS1
@ast
Communication of the position ...... machinery by the protein RNPS1
@en
Communication of the position ...... machinery by the protein RNPS1
@en-gb
Communication of the position ...... machinery by the protein RNPS1
@nl
P3181
P356
P1433
P1476
Communication of the position ...... machinery by the protein RNPS1
@en
P2093
P304
P3181
P356
10.1126/SCIENCE.1062786
P407
P577
2001-09-07T00:00:00Z