Viperin (cig5), an IFN-inducible antiviral protein directly induced by human cytomegalovirus
about
The antiviral protein viperin is a radical SAM enzymeHuman cytomegalovirus directly induces the antiviral protein viperin to enhance infectivityPeroxisomes are signaling platforms for antiviral innate immunityThe N-terminal amphipathic alpha-helix of viperin mediates localization to the cytosolic face of the endoplasmic reticulum and inhibits protein secretionGolgi targeting of human guanylate-binding protein-1 requires nucleotide binding, isoprenylation, and an IFN-gamma-inducible cofactorEpstein-Barr virus (EBV) SM protein induces and recruits cellular Sp110b to stabilize mRNAs and enhance EBV lytic gene expressionDown-regulation of UCRP and UBE2L6 in BRCA2 knocked-down human breast cellsViperin: a multifunctional, interferon-inducible protein that regulates virus replicationMechanistic and functional versatility of radical SAM enzymesThe antiviral protein viperin inhibits hepatitis C virus replication via interaction with nonstructural protein 5AIdentification of three interferon-inducible cellular enzymes that inhibit the replication of hepatitis C virusDelayed polarization of mononuclear phagocyte transcriptional program by type I interferon isoformsHost restriction factors for hepatitis C virusHost Gene Expression Profiling of Dengue Virus Infection in Cell Lines and PatientsThe Cellular Antiviral Protein Viperin Is Attenuated by Proteasome-Mediated Protein Degradation in Japanese Encephalitis Virus-Infected CellsViperin restricts chikungunya virus replication and pathology.Identification and characterization of interferon-induced proteins that inhibit alphavirus replicationThe interferon-inducible gene viperin restricts West Nile virus pathogenesisThe presence of the iron-sulfur motif is important for the conformational stability of the antiviral protein, ViperinViperin is an iron-sulfur protein that inhibits genome synthesis of tick-borne encephalitis virus via radical SAM domain activityInterspecies transmission and host restriction of avian H5N1 influenza virus.Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humansProtective efficacy of orally administered, heat-killed Lactobacillus pentosus b240 against influenza A virus.The function and evolution of the restriction factor Viperin in primates was not driven by lentiviruses.A machine learning heuristic to identify biologically relevant and minimal biomarker panels from omics dataSurvey of transcript expression in rainbow trout leukocytes reveals a major contribution of interferon-responsive genes in the early response to a rhabdovirus infection.Viperin is induced following dengue virus type-2 (DENV-2) infection and has anti-viral actions requiring the C-terminal end of viperin.Importance of the interferon-alpha system in murine large intestine indicated by microarray analysis of commensal bacteria-induced immunological changes.Surface-enhanced Raman scattering molecular sentinel nanoprobes for viral infection diagnosticsLabel-free DNA biosensor based on SERS Molecular Sentinel on Nanowave chip.Analysis of genes induced by Sendai virus infection of mutant cell lines reveals essential roles of interferon regulatory factor 3, NF-kappaB, and interferon but not toll-like receptor 3Identification of five interferon-induced cellular proteins that inhibit west nile virus and dengue virus infections.Human influenza viruses activate an interferon-independent transcription of cellular antiviral genes: outcome with influenza A virus is unique.Identification of DreI as an antiviral factor regulated by RLR signaling pathwayViperin: a radical response to viral infectionHerpes simplex virus 1 counteracts viperin via its virion host shutoff protein UL41Interferon-stimulated genes: a complex web of host defenses.Suppression of IFN-induced transcription underlies IFN defects generated by activated Ras/MEK in human cancer cells.Adenosyl radical: reagent and catalyst in enzyme reactions.Rhinovirus induces airway epithelial gene expression through double-stranded RNA and IFN-dependent pathways
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P2860
Viperin (cig5), an IFN-inducible antiviral protein directly induced by human cytomegalovirus
description
2001 nî lūn-bûn
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2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
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2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年學術文章
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Viperin (cig5), an IFN-inducib ...... duced by human cytomegalovirus
@ast
Viperin (cig5), an IFN-inducib ...... duced by human cytomegalovirus
@en
Viperin (cig5), an IFN-inducib ...... duced by human cytomegalovirus
@en-gb
Viperin (cig5), an IFN-inducib ...... duced by human cytomegalovirus
@nl
type
label
Viperin (cig5), an IFN-inducib ...... duced by human cytomegalovirus
@ast
Viperin (cig5), an IFN-inducib ...... duced by human cytomegalovirus
@en
Viperin (cig5), an IFN-inducib ...... duced by human cytomegalovirus
@en-gb
Viperin (cig5), an IFN-inducib ...... duced by human cytomegalovirus
@nl
prefLabel
Viperin (cig5), an IFN-inducib ...... duced by human cytomegalovirus
@ast
Viperin (cig5), an IFN-inducib ...... duced by human cytomegalovirus
@en
Viperin (cig5), an IFN-inducib ...... duced by human cytomegalovirus
@en-gb
Viperin (cig5), an IFN-inducib ...... duced by human cytomegalovirus
@nl
P2860
P3181
P356
P1476
Viperin (cig5), an IFN-inducib ...... duced by human cytomegalovirus
@en
P2093
P2860
P304
P3181
P356
10.1073/PNAS.011593298
P407
P577
2001-12-18T00:00:00Z