A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP
about
An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activityC-Terminal Binding Protein: A Molecular Link between Metabolic Imbalance and Epigenetic Regulation in Breast Cancer.The receptor tyrosine kinase EphA2 is a direct target gene of hypermethylated in cancer 1 (HIC1).Hypermethylated in cancer 1 (HIC1) recruits polycomb repressive complex 2 (PRC2) to a subset of its target genes through interaction with human polycomb-like (hPCL) proteinsDiversity of LEF/TCF action in development and disease.Deciphering HIC1 control pathways to reveal new avenues in cancer therapeutics.HIC1 (Hypermethylated in Cancer 1) epigenetic silencing in tumorsRequirement for chromatin-remodeling complex in novel tumor suppressor HIC1-mediated transcriptional repression and growth control.HIC1 interacts with and modulates the activity of STAT3.Differential regulation of HIC1 target genes by CtBP and NuRD, via an acetylation/SUMOylation switch, in quiescent versus proliferating cells.DNA double-strand breaks lead to activation of hypermethylated in cancer 1 (HIC1) by SUMOylation to regulate DNA repair.
P2860
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P2860
A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP
description
2006 nî lūn-bûn
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2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2006 թվականի հուլիսին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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name
A L225A substitution in the hu ...... tion with the corepressor CtBP
@ast
A L225A substitution in the hu ...... tion with the corepressor CtBP
@en
A L225A substitution in the hu ...... tion with the corepressor CtBP
@en-gb
A L225A substitution in the hu ...... tion with the corepressor CtBP
@nl
type
label
A L225A substitution in the hu ...... tion with the corepressor CtBP
@ast
A L225A substitution in the hu ...... tion with the corepressor CtBP
@en
A L225A substitution in the hu ...... tion with the corepressor CtBP
@en-gb
A L225A substitution in the hu ...... tion with the corepressor CtBP
@nl
prefLabel
A L225A substitution in the hu ...... tion with the corepressor CtBP
@ast
A L225A substitution in the hu ...... tion with the corepressor CtBP
@en
A L225A substitution in the hu ...... tion with the corepressor CtBP
@en-gb
A L225A substitution in the hu ...... tion with the corepressor CtBP
@nl
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A L225A substitution in the hu ...... tion with the corepressor CtBP
@en
P2093
Nicolas Stankovic-Valentin
Sophie Deltour-Balerdi
P2860
P304
P356
10.1111/J.1742-4658.2006.05301.X
P407
P577
2006-06-07T00:00:00Z