FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies
about
Conserved oncogenic behavior of the FAM83 family regulates MAPK signaling in human cancerHyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83BFAM83 proteins: Fostering new interactions to drive oncogenic signaling and therapeutic resistanceLASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex.Phosphatidylcholine-specific phospholipase C inhibition down- regulates CXCR4 expression and interferes with proliferation, invasion and glycolysis in glioma cells.HER2-positive breast cancer cells expressing elevated FAM83A are sensitive to FAM83A loss.Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity.FAM83B is a novel biomarker for diagnosis and prognosis of lung squamous cell carcinoma.Geroconversion: irreversible step to cellular senescenceThe BH3-mimetic gossypol and noncytotoxic doses of valproic acid induce apoptosis by suppressing cyclin-A2/Akt/FOXO3a signaling.Quantitative Profiling of the Activity of Protein Lysine Methyltransferase SMYD2 Using SILAC-Based ProteomicsPotent EMT and CSC Phenotypes Are Induced By Oncostatin-M in Pancreatic Cancer.Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.High Expression of FAM83B Predicts Poor Prognosis in Patients with Pancreatic Ductal Adenocarcinoma and Correlates with Cell Cycle and Cell Proliferation.Cholesterol trafficking and raft-like membrane domain composition mediate scavenger receptor class B type 1-dependent lipid sensing in intestinal epithelial cells.PAWS1 controls cytoskeletal dynamics and cell migration through association with the SH3 adaptor CD2AP.Family with sequence similarity 83, member B is a predictor of poor prognosis and a potential therapeutic target for lung adenocarcinoma expressing wild-type epidermal growth factor receptor.The FAM83 family of proteins: from pseudo-PLDs to anchors for CK1 isoforms.The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms.Long intergenic non-coding RNA 00324 promotes gastric cancer cell proliferation via binding with HuR and stabilizing FAM83B expression.
P2860
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P2860
FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies
description
2013 nî lūn-bûn
@nan
2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
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name
FAM83B-mediated activation of ...... sistance to targeted therapies
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FAM83B-mediated activation of ...... sistance to targeted therapies
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FAM83B-mediated activation of ...... sistance to targeted therapies
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FAM83B-mediated activation of ...... sistance to targeted therapies
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label
FAM83B-mediated activation of ...... sistance to targeted therapies
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FAM83B-mediated activation of ...... sistance to targeted therapies
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FAM83B-mediated activation of ...... sistance to targeted therapies
@en-gb
FAM83B-mediated activation of ...... sistance to targeted therapies
@nl
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FAM83B-mediated activation of ...... sistance to targeted therapies
@ast
FAM83B-mediated activation of ...... sistance to targeted therapies
@en
FAM83B-mediated activation of ...... sistance to targeted therapies
@en-gb
FAM83B-mediated activation of ...... sistance to targeted therapies
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P2093
P2860
P3181
P356
P1433
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FAM83B-mediated activation of ...... sistance to targeted therapies
@en
P2093
Benjamin L Bryson
Chase R Foy
Courtney A Bartel
Kristy L S Miskimen
Mark W Jackson
Rocky Cipriano
P2860
P304
P3181
P356
10.18632/ONCOTARGET.1027
P407
P577
2013-05-01T00:00:00Z