HSPC117 is the essential subunit of a human tRNA splicing ligase complex
about
Circularly permuted tRNA genes: their expression and implications for their physiological relevance and developmentExperimental characterization of the human non-sequence-specific nucleic acid interactomeClassification, diagnosis and potential mechanisms in pontocerebellar hypoplasiaHuman CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system functionCLP1 founder mutation links tRNA splicing and maturation to cerebellar development and neurodegenerationA census of human soluble protein complexesAnalysis of orthologous groups reveals archease and DDX1 as tRNA splicing factorsA synthetic biology approach identifies the mammalian UPR RNA ligase RtcBhCLE/C14orf166 associates with DDX1-HSPC117-FAM98B in a novel transcription-dependent shuttling RNA-transporting complextRNA fragments in human health and diseaseRibonucleotides in bacterial DNATransfer RNA post-transcriptional processing, turnover, and subcellular dynamics in the yeast Saccharomyces cerevisiaeStructure of RNA 3′-phosphate cyclase bound to substrate RNAStructural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OHStructures of the Noncanonical RNA Ligase RtcB Reveal the Mechanism of Histidine GuanylylationA tRNA splicing operon: Archease endows RtcB with dual GTP/ATP cofactor specificity and accelerates RNA ligationBeyond tRNA cleavage: novel essential function for yeast tRNA splicing endonuclease unrelated to tRNA processing.Modulating Salmonella Typhimurium's Response to a Changing Environment through Bacterial Enhancer-Binding Proteins and the RpoN RegulonTraversing the RNA world.HSPC117 is regulated by epigenetic modification and is involved in the migration of JEG-3 cellsImpact of DNA3'pp5'G capping on repair reactions at DNA 3' ends.Unambiguous identification of miRNA:target site interactions by different types of ligation reactions.RTCB-1 mediates neuroprotection via XBP-1 mRNA splicing in the unfolded protein response pathway.The RtcB RNA ligase is an essential component of the metazoan unfolded protein response.The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cellsRtcB, a novel RNA ligase, can catalyze tRNA splicing and HAC1 mRNA splicing in vivoEffects of DNA3'pp5'G capping on 3' end repair reactions and of an embedded pyrophosphate-linked guanylate on ribonucleotide surveillance.Cutting, dicing, healing and sealing: the molecular surgery of tRNADdx1 knockout results in transgenerational wild-type lethality in mice.Novel mechanism of RNA repair by RtcB via sequential 2',3'-cyclic phosphodiesterase and 3'-Phosphate/5'-hydroxyl ligation reactions.Quality Control Pathways for Nucleus-Encoded Eukaryotic tRNA Biosynthesis and Subcellular Trafficking.Regulation of axon regeneration by the RNA repair and splicing pathway.RNA ligation in neurons by RtcB inhibits axon regeneration.RNA ligase RtcB splices 3'-phosphate and 5'-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3')pp(5')G intermediates.Metazoan tRNA introns generate stable circular RNAs in vivoRNA damage in biological conflicts and the diversity of responding RNA repair systemsCoevolution of RtcB and Archease created a multiple-turnover RNA ligaseCharacterization of 3'-Phosphate RNA Ligase Paralogs RtcB1, RtcB2, and RtcB3 from Myxococcus xanthus Highlights DNA and RNA 5'-Phosphate Capping Activity of RtcB3.The sequential 2',3'-cyclic phosphodiesterase and 3'-phosphate/5'-OH ligation steps of the RtcB RNA splicing pathway are GTP-dependentmiRNA-target chimeras reveal miRNA 3'-end pairing as a major determinant of Argonaute target specificity
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P2860
HSPC117 is the essential subunit of a human tRNA splicing ligase complex
description
2011 nî lūn-bûn
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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
HSPC117 is the essential subunit of a human tRNA splicing ligase complex
@ast
HSPC117 is the essential subunit of a human tRNA splicing ligase complex
@en
HSPC117 is the essential subunit of a human tRNA splicing ligase complex
@en-gb
HSPC117 is the essential subunit of a human tRNA splicing ligase complex
@nl
type
label
HSPC117 is the essential subunit of a human tRNA splicing ligase complex
@ast
HSPC117 is the essential subunit of a human tRNA splicing ligase complex
@en
HSPC117 is the essential subunit of a human tRNA splicing ligase complex
@en-gb
HSPC117 is the essential subunit of a human tRNA splicing ligase complex
@nl
prefLabel
HSPC117 is the essential subunit of a human tRNA splicing ligase complex
@ast
HSPC117 is the essential subunit of a human tRNA splicing ligase complex
@en
HSPC117 is the essential subunit of a human tRNA splicing ligase complex
@en-gb
HSPC117 is the essential subunit of a human tRNA splicing ligase complex
@nl
P2093
P2860
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HSPC117 is the essential subunit of a human tRNA splicing ligase complex
@en
P2093
Javier Martinez
Johannes Popow
Markus Englert
Stefan Weitzer
P2860
P3181
P356
10.1126/SCIENCE.1197847
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P50
P577
2011-02-11T00:00:00Z