CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells
about
miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifsmiRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOTThe structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complexThe interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targetsThe Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescenceBiogenesis and mechanism of action of small non-coding RNAs: insights from the point of view of structural biologyFunction and Regulation of MicroRNAs and Their Potential as Biomarkers in Paediatric Liver DiseaseCurrent prospects for RNA interference-based therapiesAnti-PABPC1 co-immunoprecipitation for examining the miRNAs directly targeting the 3'-UTR of EED mRNANocturnin suppresses igf1 expression in bone by targeting the 3' untranslated region of igf1 mRNANovel roles of the multi-functional CCR4-NOT complex in post-transcriptional regulation.Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis.Translational repression by deadenylases.To polyadenylate or to deadenylate: that is the question.The regulation of mRNA stability in mammalian cells: 2.0.The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC.Poly(A) binding proteins: are they all created equal?Translational control in germline stem cell development.HPat a decapping activator interacting with the miRNA effector complex.Limiting Ago protein restricts RNAi and microRNA biogenesis during early development in Xenopus laevis.Activation of a microRNA response in trans reveals a new role for poly(A) in translational repressionMammalian hyperplastic discs homolog EDD regulates miRNA-mediated gene silencingMicroRNA-mediated repression of nonsense mRNAs.Developmental functions of piRNAs and transposable elements: a Drosophila point-of-viewTranslational inhibition by deadenylation-independent mechanisms is central to microRNA-mediated silencing in zebrafish.Human Pumilio proteins recruit multiple deadenylases to efficiently repress messenger RNAsIntegrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory networkA molecular link between miRISCs and deadenylases provides new insight into the mechanism of gene silencing by microRNAs.Mammalian GW220/TNGW1 is essential for the formation of GW/P bodies containing miRISC.Combinatorial mRNA binding by AUF1 and Argonaute 2 controls decay of selected target mRNAs.The miRNA biogenesis in marine bivalves.MicroRNAs 24 and 27 Suppress Allergic Inflammation and Target a Network of Regulators of T Helper 2 Cell-Associated Cytokine ProductionHistology-specific microRNA alterations in melanoma.The WEE1 regulators CPEB1 and miR-15b switch from inhibitor to activators at G2/MYTHDF2 destabilizes m(6)A-containing RNA through direct recruitment of the CCR4-NOT deadenylase complex.Deadenylation and P-bodies.RNA viruses and microRNAs: challenging discoveries for the 21st century.Trip to ER: MicroRNA-mediated translational repression in plants.Antisense gene silencing: therapy for neurodegenerative disorders?Cytoplasmic deadenylation: regulation of mRNA fate.
P2860
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P248
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P2860
CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
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2010 թվականի մարտին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells
@ast
CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells
@en
CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells
@en-gb
CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells
@nl
type
label
CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells
@ast
CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells
@en
CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells
@en-gb
CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells
@nl
prefLabel
CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells
@ast
CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells
@en
CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells
@en-gb
CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells
@nl
P2093
P2860
P921
P3181
P356
P1476
CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells
@en
P2093
Joel G Belasco
Xianghua Piao
P2860
P304
P3181
P356
10.1128/MCB.01481-09
P407
P577
2010-03-01T00:00:00Z