Natural killer cell cytotoxicity is suppressed by exposure to the human NKG2D ligand MICA*008 that is shed by tumor cells in exosomes
about
Human NKG2D-ligands: cell biology strategies to ensure immune recognitionWiskott-Aldrich syndrome protein (WASp) and N-WASp are involved in the regulation of NK-cell migration upon NKG2D activationRegulation of immune cell function and differentiation by the NKG2D receptorExosomes for Immunoregulation and Therapeutic Intervention in CancerExtracellular Vesicles in Physiology, Pathology, and Therapy of the Immune and Central Nervous System, with Focus on Extracellular Vesicles Derived from Mesenchymal Stem Cells as Therapeutic ToolsImmunotherapeutic potential of extracellular vesiclesGlycosyl-Phosphatidyl-Inositol (GPI)-Anchors and Metalloproteases: Their Roles in the Regulation of Exosome Composition and NKG2D-Mediated Immune RecognitionNKG2D Ligands in Tumor Immunity: Two Sides of a CoinCharacterization of CD200 Ectodomain SheddingFormation and role of exosomes in cancer.MHC class I chain-related protein A and B (MICA and MICB) are predominantly expressed intracellularly in tumour and normal tissue.Reversal of NK-cell exhaustion in advanced melanoma by Tim-3 blockade.Neoadjuvant chemotherapy for pancreatic cancer: Effects on cancer tissue and novel perspectives.Tumor-Related Exosomes Contribute to Tumor-Promoting Microenvironment: An Immunological Perspective.Label-free quantitative detection of tumor-derived exosomes through surface plasmon resonance imagingCervical cancer cell lines expressing NKG2D-ligands are able to down-modulate the NKG2D receptor on NKL cells with functional implicationsTumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma.Regulation of ligands for the NKG2D activating receptor.Genetics, genomics, and evolutionary biology of NKG2D ligands.Vimentin in cancer and its potential as a molecular target for cancer therapy.Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta1.HPV-E7 delivered by engineered exosomes elicits a protective CD8⁺ T cell-mediated immune responseProstate tumor-derived exosomes down-regulate NKG2D expression on natural killer cells and CD8+ T cells: mechanism of immune evasion.The Impact of Glycosyl-Phosphatidyl-Inositol Anchored MICA Alleles on Novel NKG2D-Based Therapies.Biological properties of extracellular vesicles and their physiological functions.Exosomes in cancer: small particle, big player.Exosome removal as a therapeutic adjuvant in cancer.Matrine increases NKG2D ligand ULBP2 in K562 cells via inhibiting JAK/STAT3 pathway: a potential mechanism underlying the immunotherapy of matrine in leukemia.The IMiDs targets IKZF-1/3 and IRF4 as novel negative regulators of NK cell-activating ligands expression in multiple myelomaAntitumor immunity. A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection.MICA variant promotes allosensitization after kidney transplantation.The origin, function, and diagnostic potential of RNA within extracellular vesicles present in human biological fluids.Extracellular vesicle-mediated transfer of donor genomic DNA to recipient cells is a novel mechanism for genetic influence between cells.VEGFR2 targeted antibody fused with MICA stimulates NKG2D mediated immunosurveillance and exhibits potent anti-tumor activity against breast cancerTransfer of extracellular vesicles during immune cell-cell interactions.Development of a rapid lateral flow immunoassay test for detection of exosomes previously enriched from cell culture medium and body fluids.Expression and prognostic significance of unique ULBPs in pancreatic cancerPancreatic cancer diagnosis by free and exosomal miRNA.Combination immune therapies to enhance anti-tumor responses by NK cells.A disintegrin and metalloproteinases 10 and 17 modulate the immunogenicity of glioblastoma-initiating cells.
P2860
Q21131219-6943F3AB-DFA5-44BA-A362-82B5796F1495Q24322081-8EFD40A5-656B-40BD-A65B-CF268FBBCB27Q24635093-0E4AA936-4259-4B7C-957A-3F8787DA8D60Q26744193-9D514A50-E23F-40A6-AF5E-6658DEB95372Q26747560-D8C12C73-5A0B-449B-AC60-21209CEE00A5Q27023323-1499B3A6-92AD-45AA-904D-266497D3D629Q28076151-E40AE919-20E2-401F-9798-316064F9F97AQ28083832-B1DC561A-A633-499B-951F-D2266D7A37FAQ28551557-D675304E-80DB-4FCC-A53B-0CF9A3AAA132Q30303067-7DD5E455-9794-4001-A759-59220750DE22Q33639723-E411B930-953F-4E7D-9BC1-529AB11072C6Q33714165-39D32FE9-233D-48E7-B694-77715BEA994EQ33751263-4872F2E8-6A56-4E6E-94A1-331533FAF87EQ33795061-37ACB0F1-36CB-4E8F-BF0A-EE39C7E68470Q34120311-C481E9C0-C7F4-4271-8549-F1F357F60808Q34153620-8B91BFC6-6DBD-4B20-BFAF-C014ED074412Q34221714-8B62C3C3-F61B-467B-A698-4838087399BFQ34321457-9ABA2682-236D-42E9-B2DB-454DB571A154Q34489980-36C91DEC-FD7D-4531-A597-41910108464AQ35182104-4A5E9CD7-E473-4B60-A99D-5D9BEF9D9D31Q35193728-E6D3D7DC-F59D-42F7-91AB-5A8AD231AD32Q35232797-63010B83-6052-4051-B0B1-285FDDC8D5DFQ35287627-6E19803A-DD71-4F87-B2F8-F1DF70732B10Q35541002-2F69FB96-BC95-4C9A-B981-6FBF0F04C6DEQ35611763-545A0708-F9B2-4CA0-8103-7083C461BFC2Q35834473-36CF94B3-BF09-4695-9234-E326DE1F1716Q36232064-9B533C33-2A83-47FC-9F15-A47755D75F75Q36309488-687EA1FB-ED9E-47F8-B5C6-A3A73E07977BQ36414249-CB3AEA42-A42D-4897-BB5C-5FFDF95D7D4CQ36868340-3FFC55CE-6D23-4D7B-96E1-2B316D9892FBQ36880424-4220E541-F53C-4348-944F-7829FFB38B7CQ37054618-BDDB550C-46A3-4E40-A5D2-1E3BD9773A6AQ37070022-8FA125AB-9C4E-4B36-BCB8-1319BA74137FQ37086056-F73A7444-C98D-4406-9025-1662F7EF3903Q37087729-9FDFCDEE-7FCB-4C86-9E60-E5AF2146842AQ37176960-A761463A-0D49-4421-AFCE-6BE00BC36BD0Q37229770-1472D63D-11A6-4CFE-B50D-A0D8749ECCDAQ37382231-223636DC-5792-48F9-9C12-1B2374497FBBQ37408550-656A0712-E7E1-4E8C-8224-E5FC0EF298BCQ37580507-A4E83093-6ACC-4836-953D-6DD36856DB02
P2860
Natural killer cell cytotoxicity is suppressed by exposure to the human NKG2D ligand MICA*008 that is shed by tumor cells in exosomes
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Natural killer cell cytotoxici ...... hed by tumor cells in exosomes
@ast
Natural killer cell cytotoxici ...... hed by tumor cells in exosomes
@en
Natural killer cell cytotoxici ...... hed by tumor cells in exosomes
@en-gb
Natural killer cell cytotoxici ...... hed by tumor cells in exosomes
@nl
type
label
Natural killer cell cytotoxici ...... hed by tumor cells in exosomes
@ast
Natural killer cell cytotoxici ...... hed by tumor cells in exosomes
@en
Natural killer cell cytotoxici ...... hed by tumor cells in exosomes
@en-gb
Natural killer cell cytotoxici ...... hed by tumor cells in exosomes
@nl
prefLabel
Natural killer cell cytotoxici ...... hed by tumor cells in exosomes
@ast
Natural killer cell cytotoxici ...... hed by tumor cells in exosomes
@en
Natural killer cell cytotoxici ...... hed by tumor cells in exosomes
@en-gb
Natural killer cell cytotoxici ...... hed by tumor cells in exosomes
@nl
P2093
P2860
P921
P3181
P1433
P1476
Natural killer cell cytotoxici ...... hed by tumor cells in exosomes
@en
P2093
Hugh T Reyburn
Jeremy N Skepper
Lola Fernández-Messina
Omodele Ashiru
Philippe Boutet
Sonia Agüera-González
P2860
P304
P3181
P356
10.1158/0008-5472.CAN-09-1688
P407
P577
2010-01-12T00:00:00Z