c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage
about
JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damageProtein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damageMUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damageProtein kinase C delta regulates Ser46 phosphorylation of p53 tumor suppressor in the apoptotic response to DNA damageThe human Rad9 checkpoint protein stimulates the carbamoyl phosphate synthetase activity of the multifunctional protein CADInteraction and colocalization of Rad9/Rad1/Hus1 checkpoint complex with replication protein A in human cellsProtein kinase C delta activates topoisomerase IIalpha to induce apoptotic cell death in response to DNA damageTyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding.Werner syndrome protein phosphorylation by abl tyrosine kinase regulates its activity and distributionCockayne syndrome protein B interacts with and is phosphorylated by c-Abl tyrosine kinaseATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damageHuman checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cellsA role of the C-terminal region of human Rad9 (hRad9) in nuclear transport of the hRad9 checkpoint complexDNA damage response genes and the development of cancer metastasisFrag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis.BH3-only proteins in apoptosis and beyond: an overview.Localization of the Drosophila Rad9 protein to the nuclear membrane is regulated by the C-terminal region and is affected in the meiotic checkpoint.Role of BRCA1 and BRCA2 as regulators of DNA repair, transcription, and cell cycle in response to DNA damage.Phosphorylation of Rad9 at serine 328 by cyclin A-Cdk2 triggers apoptosis via interfering Bcl-xLHuman RAD9 checkpoint control/proapoptotic protein can activate transcription of p21.A role for the arginine methylation of Rad9 in checkpoint control and cellular sensitivity to DNA damage.Targeted deletion of Rad9 in mouse skin keratinocytes enhances genotoxin-induced tumor development.Contributions of Rad9 to tumorigenesis.Chk1 Activation Protects Rad9A from Degradation as Part of a Positive Feedback Loop during Checkpoint Signalling.XRad17 is required for the activation of XChk1 but not XCds1 during checkpoint signaling in Xenopus.Loss of Hus1 sensitizes cells to etoposide-induced apoptosis by regulating BH3-only proteins.Potential utility of small tyrosine kinase inhibitors in the treatment of diabetes.Does the small tyrosine kinase inhibitor Imatinib mesylate counteract diabetes by affecting pancreatic islet amyloidosis and fibrosis?LmHus1 is required for the DNA damage response in Leishmania major and forms a complex with an unusual Rad9 homologue.p53 and RAD9, the DNA Damage Response, and Regulation of Transcription Networks.DNA damage signalling recruits RREB-1 to the p53 tumour suppressor promoter.Human hRad1 but not hRad9 protects hHus1 from ubiquitin-proteasomal degradation.Caspase-3-mediated cleavage of Rad9 during apoptosis.Phosphorylation of human Rad9 is required for genotoxin-activated checkpoint signaling.Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethalityTip60-mediated acetylation activates transcription independent apoptotic activity of Abl.c-Abl tyrosine kinase in the DNA damage response: cell death and moreActivation of SAPK/JNK signaling by protein kinase Cdelta in response to DNA damage.Rad9 protects cells from topoisomerase poison-induced cell death.
P2860
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P2860
c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage
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2002 nî lūn-bûn
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2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2002 թվականի մայիսին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
@zh-hk
2002年論文
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2002年論文
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2002年论文
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name
c-Abl tyrosine kinase regulate ...... tein in response to DNA damage
@ast
c-Abl tyrosine kinase regulate ...... tein in response to DNA damage
@en
c-Abl tyrosine kinase regulate ...... tein in response to DNA damage
@en-gb
c-Abl tyrosine kinase regulate ...... tein in response to DNA damage
@nl
type
label
c-Abl tyrosine kinase regulate ...... tein in response to DNA damage
@ast
c-Abl tyrosine kinase regulate ...... tein in response to DNA damage
@en
c-Abl tyrosine kinase regulate ...... tein in response to DNA damage
@en-gb
c-Abl tyrosine kinase regulate ...... tein in response to DNA damage
@nl
prefLabel
c-Abl tyrosine kinase regulate ...... tein in response to DNA damage
@ast
c-Abl tyrosine kinase regulate ...... tein in response to DNA damage
@en
c-Abl tyrosine kinase regulate ...... tein in response to DNA damage
@en-gb
c-Abl tyrosine kinase regulate ...... tein in response to DNA damage
@nl
P2093
P2860
P921
P1476
c-Abl tyrosine kinase regulate ...... tein in response to DNA damage
@en
P2093
Donald Kufe
Kiyoshi Komatsu
Kiyotsugu Yoshida
P2860
P304
P356
10.1128/MCB.22.10.3292-3300.2002
P407
P577
2002-05-01T00:00:00Z