siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle
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Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advancesActivation of Wnt/beta-catenin signaling increases insulin sensitivity through a reciprocal regulation of Wnt10b and SREBP-1c in skeletal muscle cellsAnkrd2/ARPP is a novel Akt2 specific substrate and regulates myogenic differentiation upon cellular exposure to H(2)O(2)Phosphorylation of Ser357 of rat insulin receptor substrate-1 mediates adverse effects of protein kinase C-delta on insulin action in skeletal muscle cellsInsulin receptor signaling in normal and insulin-resistant statesInsulin signaling regulates fatty acid catabolism at the level of CoA activationNovel Endogenous, Insulin-Stimulated Akt2 Protein Interaction Partners in L6 MyoblastsThe actin-bundling protein palladin is an Akt1-specific substrate that regulates breast cancer cell migrationSystems analysis of transcriptional data provides insights into muscle's biological response to botulinum toxin.Altered PI3-kinase/Akt signalling in skeletal muscle of young men with low birth weight.Prolonged activation of S6K1 does not suppress IRS or PI-3 kinase signaling during muscle cell differentiation.Differential effects of protein kinase B/Akt isoforms on glucose homeostasis and islet mass.2D-DIGE proteomic analysis of vastus lateralis from COPD patients with low and normal fat free mass index and healthy controlsThe GLUT4 codeFunctional characterization of a haplotype in the AKT1 gene associated with glucose homeostasis and metabolic syndrome.Bimodal effect on pancreatic β-cells of secretory products from normal or insulin-resistant human skeletal muscleMicroRNA-185 regulates expression of lipid metabolism genes and improves insulin sensitivity in mice with non-alcoholic fatty liver disease.High rates of muscle glycogen resynthesis after exhaustive exercise when carbohydrate is coingested with caffeine.A non-erythropoietic peptide derivative of erythropoietin decreases susceptibility to diet-induced insulin resistance in mice.Deep proteomics of mouse skeletal muscle enables quantitation of protein isoforms, metabolic pathways, and transcription factors.Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis.AMPK and Exercise: Glucose Uptake and Insulin Sensitivity.Calorie restriction leads to greater Akt2 activity and glucose uptake by insulin-stimulated skeletal muscle from old rats.Mechanisms for greater insulin-stimulated glucose uptake in normal and insulin-resistant skeletal muscle after acute exercise.siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle.Role of Akt substrate of 160 kDa in insulin-stimulated and contraction-stimulated glucose transport.Satellite cell proliferation is reduced in muscles of obese Zucker rats but restored with loading.Regulation of IRS1/Akt insulin signaling by microRNA-128a during myogenesis.High sugar intake and development of skeletal muscle insulin resistance and inflammation in mice: a protective role for PPAR- δ agonismThe genetic regulatory signature of type 2 diabetes in human skeletal muscle.Inhibition of contraction-stimulated AMP-activated protein kinase inhibits contraction-stimulated increases in PAS-TBC1D1 and glucose transport without altering PAS-AS160 in rat skeletal muscle.Biomarkers of response to Akt inhibitor MK-2206 in breast cancerAkt2 influences glycogen synthase activity in human skeletal muscle through regulation of NH₂-terminal (sites 2 + 2a) phosphorylationImpairments in site-specific AS160 phosphorylation and effects of exercise training.Developmental programming in skeletal muscle in response to overnourishment in the immediate postnatal life in rats.Exercise-induced phospho-proteins in skeletal muscle.Insulin receptor substrate-1/2 mediates IL-4-induced migration of human airway epithelial cellsAltered skeletal muscle insulin signaling and mitochondrial complex II-III linked activity in adult offspring of obese mice.Interactome-transcriptome analysis discovers signatures complementary to GWAS Loci of Type 2 DiabetesDistinct actions of Akt1 and Akt2 in skeletal muscle differentiation.
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P2860
siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle
description
2006 nî lūn-bûn
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2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
siRNA-based gene silencing rev ...... olism in human skeletal muscle
@ast
siRNA-based gene silencing rev ...... olism in human skeletal muscle
@en
siRNA-based gene silencing rev ...... olism in human skeletal muscle
@en-gb
siRNA-based gene silencing rev ...... olism in human skeletal muscle
@nl
type
label
siRNA-based gene silencing rev ...... olism in human skeletal muscle
@ast
siRNA-based gene silencing rev ...... olism in human skeletal muscle
@en
siRNA-based gene silencing rev ...... olism in human skeletal muscle
@en-gb
siRNA-based gene silencing rev ...... olism in human skeletal muscle
@nl
prefLabel
siRNA-based gene silencing rev ...... olism in human skeletal muscle
@ast
siRNA-based gene silencing rev ...... olism in human skeletal muscle
@en
siRNA-based gene silencing rev ...... olism in human skeletal muscle
@en-gb
siRNA-based gene silencing rev ...... olism in human skeletal muscle
@nl
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P50
P921
P3181
P1433
P1476
siRNA-based gene silencing rev ...... olism in human skeletal muscle
@en
P2093
Anna Zachrisson
Bei B Zhang
Karim Bouzakri
Lubna Al-Khalili
P3181
P356
10.1016/J.CMET.2006.04.008
P407
P577
2006-07-01T00:00:00Z