Human TRPV4 channel splice variants revealed a key role of ankyrin domains in multimerization and trafficking
about
ANKRD13C acts as a molecular chaperone for G protein-coupled receptorsThe HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channelsAlterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2CTRPV1 and Endocannabinoids: Emerging Molecular Signals that Modulate Mammalian VisionMutations in TRPV4 cause Charcot-Marie-Tooth disease type 2CCrystal structure of the N-terminal ankyrin repeat domain of TRPV3 reveals unique conformation of finger 3 loop critical for channel functionTRPV4 channel activity is modulated by direct interaction of the ankyrin domain to PI(4,5)P₂Heteromerization of TRP channel subunits: extending functional diversityTRPV channels and vascular functionTRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells.Dominant mutations in the cation channel gene transient receptor potential vanilloid 4 cause an unusual spectrum of neuropathiesScapuloperoneal spinal muscular atrophy and CMT2C are allelic disorders caused by alterations in TRPV4.The puzzle of TRPV4 channelopathies.Conditional fast expression and function of multimeric TRPV5 channels using Shield-1.Interdomain interactions control Ca2+-dependent potentiation in the cation channel TRPV4TRPV4-associated skeletal dysplasias.The increased activity of TRPV4 channel in the astrocytes of the adult rat hippocampus after cerebral hypoxia/ischemia.An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes.Transient receptor potential channel activation and endothelium-dependent dilation in the systemic circulation.IP3 receptor binds to and sensitizes TRPV4 channel to osmotic stimuli via a calmodulin-binding site.Shear stress mediates exocytosis of functional TRPV4 channels in endothelial cells.Prostate cell differentiation status determines transient receptor potential melastatin member 8 channel subcellular localization and function.Activation of endothelial TRPV4 channels mediates flow-induced dilation in human coronary arterioles: role of Ca2+ entry and mitochondrial ROS signaling.Polymodal Transient Receptor Potential Vanilloid (TRPV) Ion Channels in Chondrogenic CellsUnusual localization and translocation of TRPV4 protein in cultured ventricular myocytes of the neonatal rat.Human skeletal dysplasia caused by a constitutive activated transient receptor potential vanilloid 4 (TRPV4) cation channel mutation.IP3 sensitizes TRPV4 channel to the mechano- and osmotransducing messenger 5'-6'-epoxyeicosatrienoic acid.A TRPV4 channel C-terminal folding recognition domain critical for trafficking and function.Rhythmic Trafficking of TRPV2 in the Suprachiasmatic Nucleus is Regulated by Prokineticin 2 SignalingPhosphatidylinositol-4,5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli.Receptor and channel heteromers as pain targets.Transient receptor potential vanilloid type 4-deficient mice exhibit impaired endothelium-dependent relaxation induced by acetylcholine in vitro and in vivoA loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremiaRegulation of the epithelial sodium channel [ENaC] in kidneys of salt-sensitive Dahl rats: insights on alternative splicing.Molecular mechanism of TRP channelsTRP channels.Trafficking of ThermoTRP Channels.TRPV4: physiological role and therapeutic potential in respiratory diseases.Role of the transient receptor potential vanilloid 5 (TRPV5) protein N terminus in channel activity, tetramerization, and trafficking.Constant change: dynamic regulation of membrane transport by calcium signalling networks keeps plants in tune with their environment.
P2860
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P2860
Human TRPV4 channel splice variants revealed a key role of ankyrin domains in multimerization and trafficking
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Human TRPV4 channel splice var ...... ultimerization and trafficking
@ast
Human TRPV4 channel splice var ...... ultimerization and trafficking
@en
Human TRPV4 channel splice var ...... ultimerization and trafficking
@en-gb
Human TRPV4 channel splice var ...... ultimerization and trafficking
@nl
type
label
Human TRPV4 channel splice var ...... ultimerization and trafficking
@ast
Human TRPV4 channel splice var ...... ultimerization and trafficking
@en
Human TRPV4 channel splice var ...... ultimerization and trafficking
@en-gb
Human TRPV4 channel splice var ...... ultimerization and trafficking
@nl
prefLabel
Human TRPV4 channel splice var ...... ultimerization and trafficking
@ast
Human TRPV4 channel splice var ...... ultimerization and trafficking
@en
Human TRPV4 channel splice var ...... ultimerization and trafficking
@en-gb
Human TRPV4 channel splice var ...... ultimerization and trafficking
@nl
P2093
P356
P1476
Human TRPV4 channel splice var ...... ultimerization and trafficking
@en
P2093
Maite Arniges
Michael Schaefer
Nadine Albrecht
P304
P356
10.1074/JBC.M511456200
P407
P577
2005-11-16T00:00:00Z