A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transport
about
Rab1a and Rab5a preferentially bind to binary lipid compositions with higher stored curvature elastic energyJRAB/MICAL-L2 is a junctional Rab13-binding protein mediating the endocytic recycling of occludinIn vitro reconstitution of a transport complex containing Rab27a, melanophilin and myosin VaGriscelli syndrome restricted to hypopigmentation results from a melanophilin defect (GS3) or a MYO5A F-exon deletion (GS1)Identification and characterization of multiple novel Rab-myosin Va interactionsRab27a and Rab27b control different steps of the exosome secretion pathwayThe Rab27a-binding protein, JFC1, regulates androgen-dependent secretion of prostate-specific antigen and prostatic-specific acid phosphataseFunctional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndromeCargos and genes: insights into vesicular transport from inherited human diseaseRapid degradation of dominant-negative Rab27 proteins in vivo precludes their use in transgenic mouse models.New Insights into How Trafficking Regulates T Cell Receptor SignalingRab and Arf proteins in genetic diseasesThe many different cellular functions of MYO7A in the retinaRegulation of vesicular trafficking and leukocyte function by Rab27 GTPases and their effectorsMyosin Vb mediated plasma membrane homeostasis regulates peridermal cell size and maintains tissue homeostasis in the zebrafish epidermisMelanosomal dynamics assessed with a live-cell fluorescent melanosomal markerDistinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cellsMelanosome transfer: it is best to give and receiveUpdate on the regulation of mammalian melanocyte function and skin pigmentationMelanophilin and myosin Va track the microtubule plus end on EB1Myosin-Va transports the endoplasmic reticulum into the dendritic spines of Purkinje neuronsRabphilin and Noc2 are recruited to dense-core vesicles through specific interaction with Rab27A in PC12 cellsSlac2-c (synaptotagmin-like protein homologue lacking C2 domains-c), a novel linker protein that interacts with Rab27, myosin Va/VIIa, and actinMyosin V: regulation by calcium, calmodulin, and the tail domainRole of myosin VIIa and Rab27a in the motility and localization of RPE melanosomesThe role of Rab27a in the regulation of melanosome distribution within retinal pigment epithelial cellsEssential role of RAB27A in determining constitutive human skin colorIdentification of a minimal myosin Va binding site within an intrinsically unstructured domain of melanophilinRole of Rab GTPases in membrane traffic and cell physiologyRabs and their effectors: achieving specificity in membrane trafficProtein interactions in human genetic diseases.Rab8 regulates the actin-based movement of melanosomes.The ternary Rab27a-Myrip-Myosin VIIa complex regulates melanosome motility in the retinal pigment epithelium.Myosin Vb interacts with Rab8a on a tubular network containing EHD1 and EHD3.A general role for Rab27a in secretory cells.Exophilin8 transiently clusters insulin granules at the actin-rich cell cortex prior to exocytosis.Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Gem-interacting protein.Upregulation of the Rab27a-dependent trafficking and secretory mechanisms improves lysosomal transport, alleviates endoplasmic reticulum stress, and reduces lysosome overload in cystinosis.Rab11-FIP2 interaction with MYO5B regulates movement of Rab11a-containing recycling vesicles.
P2860
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P248
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P2860
A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transport
description
2002 nî lūn-bûn
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2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
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name
A family of Rab27-binding prot ...... nction in melanosome transport
@ast
A family of Rab27-binding prot ...... nction in melanosome transport
@en
A family of Rab27-binding prot ...... nction in melanosome transport
@en-gb
A family of Rab27-binding prot ...... nction in melanosome transport
@nl
type
label
A family of Rab27-binding prot ...... nction in melanosome transport
@ast
A family of Rab27-binding prot ...... nction in melanosome transport
@en
A family of Rab27-binding prot ...... nction in melanosome transport
@en-gb
A family of Rab27-binding prot ...... nction in melanosome transport
@nl
prefLabel
A family of Rab27-binding prot ...... nction in melanosome transport
@ast
A family of Rab27-binding prot ...... nction in melanosome transport
@en
A family of Rab27-binding prot ...... nction in melanosome transport
@en-gb
A family of Rab27-binding prot ...... nction in melanosome transport
@nl
P2093
P2860
P921
P3181
P356
P1476
A family of Rab27-binding prot ...... nction in melanosome transport
@en
P2093
Abul K Tarafder
Alistair N Hume
Eleni Barkagianni
Miguel C Seabra
Molly Strom
P2860
P304
P3181
P356
10.1074/JBC.M202574200
P407
P577
2002-07-12T00:00:00Z