Human Bub1 defines the persistent cohesion site along the mitotic chromosome by affecting Shugoshin localization
about
Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repairTripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachmentsStructural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interactionThe acetyltransferase activity of San stabilizes the mitotic cohesin at the centromeres in a shugoshin-independent mannerShugoshin collaborates with protein phosphatase 2A to protect cohesinsSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1CENP-V is required for centromere organization, chromosome alignment and cytokinesis.A nucleolar protein RRS1 contributes to chromosome congressionBub1 regulates chromosome segregation in a kinetochore-independent mannerHuman Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophaseThe chromosome cycle: coordinating replication and segregation. Second in the cycles review series.Structure and function of the PP2A-shugoshin interactionSeparase is recruited to mitotic chromosomes to dissolve sister chromatid cohesion in a DNA-dependent mannerChromatid cohesion defects may underlie chromosome instability in human colorectal cancersThe crystal structure of the N-terminal region of BUB1 provides insight into the mechanism of BUB1 recruitment to kinetochoresShugoshin enables tension-generating attachment of kinetochores by loading Aurora to centromeresBub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesisBub1 is essential for assembly of the functional inner centromere.The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint SignalingAn Ancient Yeast for Young Geneticists: A Primer on the Schizosaccharomyces pombe Model SystemCohesin is dispensable for centromere cohesion in human cellsPIASgamma is required for faithful chromosome segregation in human cellsSgo1 recruits PP2A to chromosomes to ensure sister chromatid bi-orientation during mitosis.The core centromere and Sgo1 establish a 50-kb cohesin-protected domain around centromeres during meiosis IBub1 kinase targets Sgo1 to ensure efficient chromosome biorientation in budding yeast mitosis.Phosphorylation of H2A by Bub1 prevents chromosomal instability through localizing shugoshinA conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosisRole of cleavage by separase of the Rec8 kleisin subunit of cohesin during mammalian meiosis I.SGO1 maintains bovine meiotic and mitotic centromeric cohesions of sister chromatids and directly affects embryo developmentThe V260I mutation in fission yeast alpha-tubulin Atb2 affects microtubule dynamics and EB1-Mal3 localization and activates the Bub1 branch of the spindle checkpoint.Systematic analysis in Caenorhabditis elegans reveals that the spindle checkpoint is composed of two largely independent branches.Ska3 is required for spindle checkpoint silencing and the maintenance of chromosome cohesion in mitosisCohesion fatigue induces chromatid separation in cells delayed at metaphase.Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylationHistone h3 exerts a key function in mitotic checkpoint control.Haspin: a newly discovered regulator of mitotic chromosome behavior.Reduced ability to recover from spindle disruption and loss of kinetochore spindle assembly checkpoint proteins in oocytes from aged mice.Phosphorylation of mammalian Sgo2 by Aurora B recruits PP2A and MCAK to centromeresPhosphorylation-enabled binding of SGO1-PP2A to cohesin protects sororin and centromeric cohesion during mitosis.
P2860
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P2860
Human Bub1 defines the persistent cohesion site along the mitotic chromosome by affecting Shugoshin localization
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Human Bub1 defines the persist ...... fecting Shugoshin localization
@ast
Human Bub1 defines the persist ...... fecting Shugoshin localization
@en
Human Bub1 defines the persist ...... fecting Shugoshin localization
@en-gb
Human Bub1 defines the persist ...... fecting Shugoshin localization
@nl
type
label
Human Bub1 defines the persist ...... fecting Shugoshin localization
@ast
Human Bub1 defines the persist ...... fecting Shugoshin localization
@en
Human Bub1 defines the persist ...... fecting Shugoshin localization
@en-gb
Human Bub1 defines the persist ...... fecting Shugoshin localization
@nl
prefLabel
Human Bub1 defines the persist ...... fecting Shugoshin localization
@ast
Human Bub1 defines the persist ...... fecting Shugoshin localization
@en
Human Bub1 defines the persist ...... fecting Shugoshin localization
@en-gb
Human Bub1 defines the persist ...... fecting Shugoshin localization
@nl
P2093
P3181
P1433
P1476
Human Bub1 defines the persist ...... fecting Shugoshin localization
@en
P2093
Miho Ohsugi
Tadashi Yamamoto
Yoshinori Watanabe
P3181
P356
10.1016/J.CUB.2004.12.044
P407
P577
2005-02-22T00:00:00Z