Cloning and substrate specificity of a human phenol UDP-glucuronosyltransferase expressed in COS-7 cells
about
Cloning and stable expression of a new member of the human liver phenol/bilirubin: UDP-glucuronosyltransferase cDNA familyRegulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagusPolymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestineExpression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic UGT1A8Chromosomal mapping of a human phenol UDP-glucuronosyltransferase, GNT1Identification of a rat oltipraz-inducible UDP-glucuronosyltransferase (UGT1A7) with activity towards benzo(a)pyrene-7,8-dihydrodiolXenobiotic responsive element-mediated transcriptional activation in the UDP-glucuronosyltransferase family 1 gene complexChromosomal assignment of human phenol and bilirubin UDP-glucuronosyltransferase genes (UGT1A-subfamily)Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulumUse of cloned and expressed human liver UDP-glucuronosyltransferases for analysis of drug glucuronide formation and assessment of drug toxicity.Searching for tissue-specific expression pattern-linked nucleotides of UGT1A isoformsmtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft.Structural and functional studies of UDP-glucuronosyltransferases.Immunochemical analysis of uridine diphosphate-glucuronosyltransferase in four patients with the Crigler-Najjar syndrome type I.Pharmacokinetics and molecular detoxicationPharmacogenomics of human UDP-glucuronosyltransferase enzymes.Cosegregation of intragenic markers with a novel mutation that causes Crigler-Najjar syndrome type I: implication in carrier detection and prenatal diagnosisIdentification of a genetic alteration in the code for bilirubin UDP-glucuronosyltransferase in the UGT1 gene complex of a Crigler-Najjar type I patient.Polymorphisms of Phase I and Phase II Enzymes and Breast Cancer Risk.Altered coding for a strictly conserved di-glycine in the major bilirubin UDP-glucuronosyltransferase of a Crigler-Najjar type I patient.The UGT1A6_19_GG genotype is a breast cancer risk factor.Roles of UDP-glucuronosyltransferases in chemical carcinogenesis.Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.Takashi Iyanagi: UGT1 gene complex: from Gunn rat to human.Induction of drug-metabolizing enzymes by xenobiotics.Functional impact and prevalence of polymorphisms involved in the hepatic glucuronidation of valproic acid.Transcriptional regulation of human UDP-glucuronosyltransferase genes.Cloning and characterization of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 gene promoters: differential regulation through an interior-like region.Systematic screening for polymorphisms within the UGT1A6 gene in three Chinese populations and function prediction through structural modeling.Biotransformation of xenobiotics in the human colon and rectum and its association with colorectal cancer.Expression of a functionally active human hepatic UDP-glucuronosyltransferase (UGT1A6) lacking the N-terminal signal sequence in the endoplasmic reticulum.Inhibition of human and rabbit liver steroid and xenobiotic UDP-glucuronosyltransferases by tertiary amine drugs--implications for adverse drug reactions.Characterisation of a human bilirubin UDP-glucuronosyltransferase stably expressed in hamster lung fibroblast cell cultures.Structure and function of uridine diphosphate glucuronosyltransferases.Species and tissue differences in serotonin glucuronidation.The novel UGT1 gene complex links bilirubin, xenobiotics, and therapeutic drug metabolism by encoding UDP-glucuronosyltransferase isozymes with a common carboxyl terminus.Expression of UGT1A subfamily in rat brain.Expression of the human UDP-glucuronosyltransferase UGT1*6 in Escherichia coli. Influence of bacterial signal peptides on the production and localization of the recombinant protein.Glucuronidation: driving factors and their impact on glucuronide disposition
P2860
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P2860
Cloning and substrate specificity of a human phenol UDP-glucuronosyltransferase expressed in COS-7 cells
description
1988 nî lūn-bûn
@nan
1988 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Cloning and substrate specific ...... erase expressed in COS-7 cells
@ast
Cloning and substrate specific ...... erase expressed in COS-7 cells
@en
Cloning and substrate specific ...... erase expressed in COS-7 cells
@en-gb
Cloning and substrate specific ...... erase expressed in COS-7 cells
@nl
type
label
Cloning and substrate specific ...... erase expressed in COS-7 cells
@ast
Cloning and substrate specific ...... erase expressed in COS-7 cells
@en
Cloning and substrate specific ...... erase expressed in COS-7 cells
@en-gb
Cloning and substrate specific ...... erase expressed in COS-7 cells
@nl
prefLabel
Cloning and substrate specific ...... erase expressed in COS-7 cells
@ast
Cloning and substrate specific ...... erase expressed in COS-7 cells
@en
Cloning and substrate specific ...... erase expressed in COS-7 cells
@en-gb
Cloning and substrate specific ...... erase expressed in COS-7 cells
@nl
P2093
P2860
P356
P1476
Cloning and substrate specific ...... erase expressed in COS-7 cells
@en
P2093
B Burchell
M R Jackson
S Fournel-Gigleux
P2860
P304
P356
10.1073/PNAS.85.22.8381
P407
P577
1988-11-01T00:00:00Z